Navigation Links
Amarin Signs Agreement to Acquire Ester Neurosciences
Date:12/5/2007

l Property

Ester's patent estate protects its novel technology platform with both issued patents and pending patent applications. EN101 is protected by an issued composition of matter patent in the United States that runs to 2022, and has patent protection pending in a number of other jurisdictions around the world, including Europe.

Technology Platform

Ester's therapeutic platform is based on novel and proprietary discoveries in the field of acetylcholinesterase ("AChE"), developed by Professor Hermona Soreq of the Hebrew University of Jerusalem. AChE is a degrading enzyme of the neurotransmitter acetylcholine, the imbalance of which plays a central role in a range of currently incurable and highly debilitating neurodegenerative conditions. The basic premise of Ester's therapeutic paradigm is the modulation of the "read-through" isoform of acetylcholinesterase ("AChE-R"), an excess of which plays a fundamental detrimental role in the CNS and inflammatory processes.

Ester's technology platform also exhibits anti-inflammatory effects, including an indirect inhibitory effect on key pro-inflammatory cytokines via modulation of AChE-R, as well as a direct anti-inflammatory effect via modulation of macrophage activity mediated by interaction with the toll-like receptor or TLR signalling pathway.

Ester Integration

Preparations for the integration of Ester and Amarin have already begun. Amarin is not acquiring any facilities or office space in Israel. The management of Ester's programs and research and development activity is being transitioned to Amarin's research and development team in Oxford, England. To facilitate this transition to Amarin, Eli Hazum, Chief Executive Officer of Ester, will act as a consultant to Amarin for a period of at least six months.

Acquisition Consideration

Under the terms of the acquisition agreement, Amarin will acquire 100% of the issued share capital of Ester for initial consideration
'/>"/>

SOURCE Amarin Corporation Plc
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11

Related biology technology :

1. Amarin Announces Publication of Pre-Clinical Memory Data in Journal of Neurochemistry
2. Amarin to Present at 4th Annual Bio Investor Forum
3. Amarin Announces Initiation of Cardiovascular Development Strategy
4. Amarin Corporation to Present at Acumen BioFin Rodman & Renshaw Ninth Annual Healthcare Conference
5. BioMaxx Systems Inc. Signs Engagement Letter With Alcofuel Technologies for Provision of an Ethanol Micro-Refinery
6. China-Biotics, Inc. Signs Intention Agreement to Supply Probiotics to Bright Dairy & Food Co., Ltd.
7. Avicena Signs Worldwide Exclusive Distribution Agreement with RITA Corporation for its Proprietary Dermaceutical Compounds
8. Monsanto Company Signs Share Subscription Agreement With Devgen
9. CryoLife Signs Distribution Agreement for Inclusion of BioGlue(R) Surgical Adhesive in Hernia Repair Kit with Proxy Biomedical Surgical Meshes
10. Shandong Zhouyuan Seed and Nursery Co., Ltd. Signs an Agreement with Linyi Company
11. Spanish Research Consortium Signs Four-Year Renewal Deal for ISI Web of Knowledge
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/20/2015)... 20, 2015  Select Medical Corporation ("Select") (NYSE: ... Commission granted early termination of the waiting period ... 1976, as amended, applicable to the acquisition of ... joint venture that Select has created with Welsh, ... previously announced, MJ Acquisition Corporation has signed a ...
(Date:5/20/2015)... (PRWEB) May 20, 2015 Agricultural firm ... anniversary of its acquisition of Tiger-Sul. Since the ... (Calgary Alberta, Canada) in May 2005, H.J. Baker has ... build it into a comprehensive portfolio of product offerings ... of H.J. Baker and the innovation of Tiger-Sul, transforming ...
(Date:5/20/2015)... DIEGO , May 20, 2015  Cypher ... announced a collaboration with Celgene Corporation to apply ... genomic biomarkers that associate with patient response to ... is intended to help accelerate patient access to ... efficiencies in clinical research and development and potentially ...
(Date:5/20/2015)... PARK, North Carolina , 20. ... führende Unternehmen für klinische Logistik (Clinical ... für das Geschäftsjahr 2014, das am ... eingereicht. Das Unternehmen hat die Marktentwicklung ... Logo - http://photos.prnewswire.com/prnh/20110930/NY78064LOGO ...
Breaking Biology Technology:Select Medical Corporation's Proposed Acquisition of Concentra Inc. through Joint Venture with Welsh Carson Receives Antitrust Clearance 2Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 2Agricultural Firm H.J. Baker & Bro., Inc., Celebrates 10 Years Since Acquisition Of Tiger-Sul 3Cypher Genomics Collaborates with Celgene Corporation to Identify Novel Genomic Biomarkers 2Marken schließt Ergebnisse für das Geschäftsjahr 2014 ab 2
... LOUIS, June 5 /PRNewswire-FirstCall/ -- Express Scripts, ... at the William Blair Growth Stock Conference on Thursday, June 11, ... Chicago. , , This presentation will also be broadcast ... section of Express Scripts web site at http://www.express-scripts.com ...
... , For the second time in three years, ... recognized American Biotech Labs(R) as Utah,s top, company ... UT, June 4 /PRNewswire/ - American Biotech Labs, LLC (ABL), developer ... nano-catalytic SilverSol Technology(R), today announced that the company has won the ...
... (Nasdaq: ARNA ) announced today that the ... Sciences Conference on June 11, 2009 at 11:00 a.m. Eastern Time ... Hotel in New York City. Robert E. Hoffman, Arena,s Vice President, ... of the company, including its clinical development and research programs. , ...
Cached Biology Technology:Express Scripts to Present at William Blair Growth Stock Conference 2American Biotech Labs(R) Garners 2009 Utah Best of State Award 2American Biotech Labs(R) Garners 2009 Utah Best of State Award 3Arena Pharmaceuticals to Present at the 8th Annual Needham Life Sciences Conference 2Arena Pharmaceuticals to Present at the 8th Annual Needham Life Sciences Conference 3
(Date:4/14/2015)... NEW YORK , April 14, 2015 /PRNewswire/ ... Fast IDentity Online (FIDO ® ) Alliance tm ... standards-based specifications. FIDO members commit to share technology ... authentication methods that are interoperable, more secure and ... specifications enable biometric identity verification that protects sensitive ...
(Date:4/13/2015)... , April 13, 2015  higi, a leading ... ways to more fully engage with their communities around ... industry-leading, privacy protected and secure API.  ... enables the most accessible, affordable, and convenient vehicle to ... The API will allow ...
(Date:4/8/2015)... 2015  Infinisource, a leading provider of SaaS-based Human ... a leading supplier of biometric identification and security ... most advanced biometrically-enabled time clock, the companies announced ... is setting a bold, new standard for the ... small and mid-size employer. When connected to the ...
Breaking Biology News(10 mins):HYPR Corp. Joins the FIDO Alliance 2HYPR Corp. Joins the FIDO Alliance 3higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 2higi Launches Seamless Access to HIPAA-Compliant Health Outcomes and Activity Data 3iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 2iSolved Time Clock Offers Unmatched Accuracy due to Morpho Biometrics 3
... marine food chain, albatrosses accumulate toxic contaminants such as ... study has found dramatic differences in contaminant levels between ... areas of the North Pacific. Researchers also found that ... species over the past ten years. , The differences ...
... State University professor Dr. Patrick D. Lorch, have revealed ... Mormon crickets in western North America. , ... a fear of cannibalism, drives the mass migration of ... their seasonal migration, millions of Mormon crickets (relatives of ...
... of years ago, humans began scrubbing off and discarding ... white kernel beneath. Now, for the first time, scientists ... rice processing, called rice bran, significantly lowers blood pressure ... The team reports their findings in the March 8 ...
Cached Biology News:Vegetables inhibit growth of prostate cancer in mice with human tumors 2Vegetables inhibit growth of prostate cancer in mice with human tumors 3How nice, brown rice: Study shows rice bran lowers blood pressure in rats 2
... acid gel stain has bright fluorescence when bound ... it ideal for detecting dsDNA in gels using ... Green I nucleic acid stain has also ... assays and bandshift assays. A 500 µL unit ...
... techniques are defined by the author of ... This valuable hardcover guide includes hundreds of ... references. More than 300 pages detail the ... preparation from selection and design of ...
... proteomic service includes protein separation by ... the PDQuest software package from Bio-Rad ... spectrometry. In order to meet customers ... data analysis and format of the ...
... PerkinElmer kit provides reagents for immune complex ... and plasma samples using a combination of ... then neutralized and transferred to microplate wells ... mouse monoclonal antibody to HIV-1 p24. The ...
Biology Products: