Navigation Links
Alimera Sciences Begins Pilot Study to Assess Safety and Efficacy of Iluvien(TM) in Patients With Bilateral Geographic Atrophy Due to AMD
Date:12/11/2008

ATLANTA, Dec. 11 /PRNewswire/ -- Alimera Sciences Inc., a privately held biopharmaceutical company that specializes in the research, development and commercialization of prescription ophthalmic pharmaceuticals, today reported that enrollment has begun for a pilot study to assess the safety and efficacy of Iluvien(TM) in patients with bilateral geographic atrophy (GA) secondary to age-related macular degeneration (AMD).

The pilot study will compare two doses of Iluvien (0.23 and 0.45 micrograms per day) to sham injection in patients with bilateral geographic atrophy secondary to AMD. The change from baseline in size of geographic atrophy will be assessed over time.

"The impetus for this study was the results of experiments conducted in two animal models of retinal degenerations. In both of these models, a miniaturized version of Iluvien demonstrated protective effects on the spontaneous degeneration which occurs in these animals," said Raymond Iezzi, M.D., M.S., Scientific Director, Ligon Research Center of Vision, Assistant Professor of Ophthalmology, Vitreoretinal Service, Kresge Eye Institute, Wayne State University School of Medicine.

"These results were considered compelling enough to warrant a human study, especially for a condition for which there is no approved treatment," added Dr. Iezzi.

Iluvien, a tiny, intravitreal insert, is currently being studied in the FAME Phase III clinical trial as a way to deliver a very low dose of fluocinolone acetonide, a corticosteroid, to the retina for up to three years as a treatment for diabetic macular edema (DME). An eye care professional, using a proprietary 25-gauge inserter, places Iluvien into the vitreous in a minimally invasive, outpatient procedure.

About Alimera Sciences, Inc.

Alimera Sciences is a biopharmaceutical company that specializes in the research, development and commercialization of p
'/>"/>

SOURCE Alimera Sciences Inc.
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2

Related biology technology :

1. Alimera Sciences, pSivida Limited Amend Medidur(TM) FA Collaboration Agreement
2. Valeant to Acquire Dow Pharmaceutical Sciences, Inc. for $285 Million
3. Human Genome Sciences Announces Albuferon(R) Meets Primary Endpoint in Phase 3 Trial in Chronic Hepatitis C
4. YM BIOSCIENCES PROVIDES EU REGULATORY UPDATE
5. Parion Sciences Announces Initiation of Phase I Clinical Trial to Evaluate Safety and Tolerability of GS9411
6. CeloNova BioSciences Commercializes CATANIA(TM) Coronary Stent With NanoThin Polyzene(R)-F in Europe and Middle East
7. Advanced Life Sciences Announces Cethromycin NDA Accepted for Filing by FDA for the Treatment of Community Acquired Pneumonia
8. DuPont Applied BioSciences Selects MBI to Collaborate on Process Development and Scale-Up for New Bio-based Product
9. Ellen McDonald Joins Regado Biosciences as Senior Vice President of Business Operations and Chief Business Officer
10. Frost & Sullivan Recognizes Martek Biosciences for Unique and Customer-Focused Strategies With Customer Value Enhancement Award
11. Regado Biosciences to Present at the Piper Jaffray Health Care Conference on Tuesday, December 2, 2008

Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/24/2009)...TON,Nov.24/PRNewswire-FirstCall/--IES(Nasdaq: IESC...ationssystemsandservicesforthecommercial,industria...cialbusinessgrouphasbeenawardedacontractfromManhat...l4bio-safetylab(BSL-4)replacementfacilityattheU.S....SAMRIID)atFortDetrickinFrederick,Md. ,, ThenewU...
(Date:11/24/2009)...JAVIK,Iceland,November24/PRNewswire-FirstCall/--de...tithasreceivednoticefrom,theNasdaqStockMarketthatt...fNovember30,2009andaForm25-NSEwillbefiledwiththe,S...DE,scommonstock,fromlistingonNasdaq,unlessthecompa...nel.Thecompanyhasfiledsuchanappeal,which,willstayt...
(Date:11/24/2009)...ATEO,Calif.,Nov.24/PRNewswire-FirstCall/--Neuroges...usedondevelopingandcommercializingnovelpainmanagem...identandChiefExecutiveOfficer,isscheduledtopresent...beheldDecember1-2,2009atTheNewYorkPalaceHotelinNew...ChiefFinancialOfficer,willbeavailabletorespondtoqu...
(Date:11/24/2009)...ENTURE:HTL , TORONTO,Nov.24/PRNewswire-FirstC...CapitalInc.,aleadingproviderofadvancedlasersystems...inicmarkets,todayreportedoperationalandfinancialre...Q32009Highlights,-Revenuewas$1.46millioncomparedw...ercentcomparedwith66.1percentinQ3,2008,-Netlossred...
Breaking Biology Technology:Integrated Electrical Services Awarded Contract to Provide Electrical Systems for U.S. Army Medical Research Institute of Infectious Diseases 2deCODE Receives Delisting Notice From Nasdaq, Plans to Appeal 2deCODE Receives Delisting Notice From Nasdaq, Plans to Appeal 3NeurogesX to Present at Piper Jaffray Health Care Conference 2NeurogesX to Present at Piper Jaffray Health Care Conference 3Hamilton Thorne announces third quarter results 2Hamilton Thorne announces third quarter results 3Hamilton Thorne announces third quarter results 4Hamilton Thorne announces third quarter results 5Hamilton Thorne announces third quarter results 6Hamilton Thorne announces third quarter results 7
... Now Treat 100 Percent of Improvable Hearing-Impai...ENIX, July 28 As a promise to his daughter, Zound...eveloping the patented,technology behind Zounds Z1...ed price-point and overall comfort is now availabl...ing Aid released this month., (Photo: http://www...
...ientists at the University of Pennsylvania have cr...tion of functional nanoscale patterns or motifs wi...gle master "plate." , Researchers took advantage...ible polymer membrane, polydimethylsiloxane, or PD...the membrane elliptically deform, and elastic inte...
...008 Conference and Awards Celebration has show of ... PITTSBURGH, July 25 With the life sciences posit...ding an advantage amidst global,competition requir...2BUSINESS 2008 Conference and Awards Celebration, ...t edge., The inaugural event will draw some 100 s...
Other Biology Technology:Zounds Hearing Develops and Releases Power BTE Hearing Aid 2Zounds Hearing Develops and Releases Power BTE Hearing Aid 3Penn researchers demonstrate a flexible, 1-step assembly of nanoscale structures 2Penn researchers demonstrate a flexible, 1-step assembly of nanoscale structures 3Conference to Turn Scientists of Color into PA-Based Entrepreneurs Set for November 2Conference to Turn Scientists of Color into PA-Based Entrepreneurs Set for November 3
(Date:11/26/2009)...eir impressive antlers, red deer have been caught ...,s antlers are much more than decorative. They are...lling. John Currey, from The University of York, U... of bone for over half a century and has become fa...rough a long-standing collaboration with Tomas Lan...
(Date:11/26/2009)...llin-resistant Staphylococcus Aureus ) and other ... low-temperature plasma prototype devices have bee...ng bactericidal cocktails. , Two prototype devic...tion of healthy skin (e.g. hands and feet) in hosp...lethal threat; and another to shoot bacteria-killi...
(Date:11/25/2009)...arisch, Head of the Cell Death Research Laboratory...y, has been awarded the prestigious Johnson & John...ng the cause of brain cell damage in Parkinson,s d...cientists in support of innovation and excellence ...conferred earlier this month at an event at the Hy...
Breaking Biology News(10 mins):Tough yet stiff deer antler is materials scientist's dream 2Plasma produces KO cocktail for MRSA 2Plasma produces KO cocktail for MRSA 3Johnson & Johnson award goes to research of the cause of brain cell damage in Parkinson's 2Environmental health chief in Milwaukee to hear citizen concerns 10107 1Environmental health chief in Milwaukee to hear citizen concerns 10107 2Research needed to learn which DCIS patients may be candidates for less invasive therapy 10105 1Research needed to learn which DCIS patients may be candidates for less invasive therapy 10105 2Research needed to learn which DCIS patients may be candidates for less invasive therapy 10105 3New Hope for Treatment of Pancreatic Cancer 58340 1New Hope for Treatment of Pancreatic Cancer 58340 2
...grow plant material and burn it. If managed well m... will be captured by the growing plants, and so ha...arbon dioxide. , Better still, the growing plants...roblems. In a review of current systems, Gran Bern...at Chalmers University of Technology in Gtenborg, ...
... flown to Mongolia the past three summers to searc...ld crew have joined him at Montana State Universit...n paleontologists. , Horner is Ameya Preserve cur...s and Regents Professor of Paleontology in Montana...eontology to be developed better," said Bolortsets...
...fference in the way males and females respond to c...plain why men are more prone to liver cancer, acco...nome-wide study that helps explain why there is su...e organ, where you wouldn,t expect to see one, sai...d lead author of a paper that appeared last month ...
Other Biology News:Biomass production -- careful planning can bring many benefits 2Mongolian paleontologists with a dream come to Montana State University 2Mongolian paleontologists with a dream come to Montana State University 3MIT: Why men are more prone to liver cancer 2
Hexokinase/ Glucose-6-Phosphate Dehydrogenase from Roche Applied Science
Hexokinase/ Glucose-6-Phosphate Dehydrogenase from Roche Applied Science
Mouse Anti-HLA DQ1, HLA DQ3 Monoclonal Antibody, Unconjugated, Clone HL-37 from Abcam
T4 DNA Ligase (HC) from Invitrogen
Biology Products: