Navigation Links
Alexza Reports 2008 First Quarter Financial Results and Updates Development of Product Candidates
Date:5/12/2008

f an in-clinic, multi-center, randomized,

double-blind, single administration, placebo-controlled Phase 2a

proof-of-concept clinical trial in 168 migraine patients with or

without aura. Three doses of AZ-104 (1.25, 2.5 and 5 mg) were

evaluated against placebo in the clinical trial. Using the IHS

4-point rating scale, the primary efficacy endpoint was pain-relief

response at 2 hours post-administration. AZ-104 met the primary

efficacy endpoint of the clinical trial for the two highest doses of

the drug compared to placebo. Statistically significant

improvements in pain response were observed in 76.7% of patients at

the 5 mg dose (p=0.02), 79.1% of patients at the 2.5 mg dose (p=0.01)

and 67.4% of patients at the 1.25 mg dose (p=0.18), compared to 51.3%

of patients receiving placebo. AZ-104 has been licensed to Symphony

Allegro and the Company has the right to repurchase all rights to this

product candidate.

-- AZ-002 (Staccato alprazolam). Alexza is developing AZ-002 for the

acute treatment of panic attacks associated with panic disorder. The

Company completed enrollment of its Phase 2a proof-of-concept clinical

trial in patients with panic disorder in April 2008. Alexza expects

to report initial results of this trial by the end of the second

quarter of 2008. AZ-002 has been licensed to Symphony Allegro and the

Company has the right to repurchase all rights to this product

candidate.

-- AZ-003 (Staccato fentanyl). Alexza is jointly developing AZ-003 with

Endo Pharmaceuticals Inc. for the treatment of breakthrough pain in

cancer and non-cancer patients. Endo is responsible for regulatory,

pre-clinical and clinical development, and for commercializing the

product in North America. Alexza is respons
'/>"/>

SOURCE Alexza Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10

Related biology technology :

1. Alexza Completes $10 Million Equity Financing with Bio*One Capital to Initiate Commercial Manufacturing in Singapore
2. Alexza to Announce 2007 Financial Results and Update Its Clinical Pipeline on Monday, March 17, 2008
3. Michael J. Simms Joins Alexza Pharmaceuticals as Senior Vice President, Operations and Manufacturing
4. Alexza Initiates First Phase 3 Clinical Trial for AZ-004 (Staccato(R) Loxapine)
5. Alexzas Corporate Presentation to be Webcast at the 10th Annual BIO CEO & Investor Conference
6. Merrill Lynch Global Pharmaceutical, Biotechnology & Medical Device Conference to Webcast Alexzas Corporate Presentation
7. Alexza Announces Partnership With Endo for AZ-003 (Staccato(R) fentanyl) in North America
8. Alexza Elects Dr. Hal V. Barron to Its Board of Directors
9. 19th Annual Piper Jaffray Health Care Conference to Webcast Alexzas Corporate Presentation
10. The 4th Annual BIO Investor Forum to Webcast Alexzas Corporate Presentation
11. MGT Capital Investments Reports First Quarter 2008 Financial Results and Provides Update on Recent Developments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)...   Ceres, Inc . (Nasdaq: CERE ... financial results for the three months ended May 31, ... Ceres reported that the company and its customers ... season in Brazil, which concluded in June, despite dry ... areas for part of the growing season. Yields of ...
(Date:7/10/2014)... the basis of psychiatric disorders has been extremely challenging ... risk but are insufficient to cause disease. Now investigators ... Press journal Cell Stem Cell describe a ... risks interact with other risk factors or environmental exposures ... research pinpoints a genetic variant that may predispose individuals ...
(Date:7/10/2014)... study by researchers at the University of Illinois ... mechanisms governing the interplay of spin and heat ... of ultrafast spintronic devices for data storage and ... as well as spin-angular momentum. In a typical ... is no spin current," explained David Cahill, a ...
(Date:1/15/2014)... Pittsburgh, PA (PRWEB) January 15, 2014 The ... Company, publisher of Food Safety Tech , an e-Journal ... has signed an agreement for the second year for the ... with Pittcon 2014. The partnership provides that the registration fee ...
Breaking Biology Technology:Ceres Announces Fiscal Third Quarter 2014 Financial Results 2Ceres Announces Fiscal Third Quarter 2014 Financial Results 3Ceres Announces Fiscal Third Quarter 2014 Financial Results 4Ceres Announces Fiscal Third Quarter 2014 Financial Results 5Ceres Announces Fiscal Third Quarter 2014 Financial Results 6Ceres Announces Fiscal Third Quarter 2014 Financial Results 7Ceres Announces Fiscal Third Quarter 2014 Financial Results 8Ceres Announces Fiscal Third Quarter 2014 Financial Results 9New strategy could uncover genes at the root of psychiatric illnesses 2University of Illinois study advances limits for ultrafast nano-devices 2Pittcon Announces Second Year Partnership With Food Safety Tech 2Pittcon Announces Second Year Partnership With Food Safety Tech 3
... Alcohol-Based Hand Sanitizer May Minimize Viral Transmission, Including ... sanitizer may significantly impact public health by minimizing ... food handlers and care providers. The researchers ... North Carolina State University, Raleigh report their findings ...
... physics professor Apparao Rao and his team are researching nano-scale ... to toxic chemicals or gases in the air. Put them ... for real-time chemical alerts in battle, in industry, in health ... extremely small devices to do this work has been something ...
... from sunlight at a modest cost is a challenge ... A paper in a special energy issue of ... describes a relatively new approach to solar cells: lacing ... in the article, this approach has the potential to ...
Cached Biology Technology:Tips from the journals of the American Society for Microbiology 2Tips from the journals of the American Society for Microbiology 3Tips from the journals of the American Society for Microbiology 4Clemson researchers advance nanoscale electromechanical sensors 2Enhancing solar cells with nanoparticles 2
(Date:7/10/2014)... COMMACK, N.Y. , July 2, 2014 ... Inc. (ABD) to announce the appointment of the world-renowned ... its Board of Directors. Dr. Ginsburg, with ... two facilities: NY Presbyterian Hospital and Good Samaritan Regional ... Breathing Pacemaker since the late 1980,s and is considered ...
(Date:7/10/2014)... -- Research and Markets ( http://www.researchandmarkets.com/research/h7h8lq/gesture ) has ... Recognition & Touch-Less Sensing (2D, 3D, Ultrasonic, IR, ... to their offering http://photos.prnewswire.com/prnh/20130307/600769 ... Sensing Market to Grow Exponentially. Touch-less sensing applications ... companies were unable to leverage this technology due ...
(Date:7/10/2014)... July 8, 2014 Fingerprint ... new design win (DW). An Asian OEM has selected FPC1021 ... production start in August 2014.   FPC is ... which has a planned date for start of mass production ... order of SEK 5M, for delivery in the first half ...
Breaking Biology News(10 mins):Avery Biomedical Devices, Inc. announces the appointment of Mark E Ginsburg, M.D. to its Board of Directors 2Global Gesture Recognition & Touch-Less Sensing (2D, 3D, Ultrasonic, IR, Capacitive) Market - Forecasts to 2020 2FPC Wins DW and Initial Ramp Order for FPC1021 Touch Sensor for Flagship Smartphone from Asian OEM 2
... cells, which can become any other kind of body cell, ... including Parkinson,s disease, multiple sclerosis and spinal cord injuries. However, ... large enough quantities to perform experiments in particular, to ... used to grow human stem cells include cells or proteins ...
... of plant physiology at the University of California, Riverside and ... , will receive the Paul Ecke Jr. Award of ... educator" at a ceremony beginning at 5 p.m., Sept. 11, ... Drive, Encinitas, Calif. "This award reflects the high regard ...
... AMES, Iowa Iowa State University researchers will use ... reveals single molecules, test technology that can detect food ... other projects with potential to grow the state,s economy. ... State,s proposal to award 10 competitive grants totaling $942,389 ...
Cached Biology News:MIT researchers develop a better way to grow stem cells 2MIT researchers develop a better way to grow stem cells 3Iowa State awards grants to develop health, energy and research technologies 2Iowa State awards grants to develop health, energy and research technologies 3Iowa State awards grants to develop health, energy and research technologies 4
... Degranulation, the secretion of cytoplasmic granules, ... inflammatory response of leukocytes (e.g. basophils, ... addition to histamine, these secretory granules ... cytokines, chemokines, and many proteases (Hallgren, ...
... Processing Service enables scientists who do not have ... software to have their biological samples tested for ... as easy as 1-2-3 Chose the ... samples from the S&S antibody menu. Send ...
... gel stain has bright fluorescence when bound to ... ideal for detecting dsDNA in gels using laser ... I nucleic gel acid stain has also ... and bandshift assays. One mL stains 100 minigels. ...
... techniques are defined by the author of ... This valuable hardcover guide includes hundreds of ... references. More than 300 pages detail the ... preparation from selection and design of ...
Biology Products: