Navigation Links
Agilis Biotherapeutics and Intrexon to Pursue Transformative Therapies for Rare Genetic Disease
Date:12/31/2013

mmon hereditary ataxia with an estimated 5,000 to 10,000 patients in the United States.   

The goal of the ECC is to develop DNA-based therapeutics to repair or replace the "broken" gene in FRDA and enable increased production of the frataxin protein to alleviate the downstream effects of frataxin deficiency. The combination of gene correction with additional therapeutic modulators in a multigenic approach has the potential to create a potent treatment.  This treatment is expected to further improve cardiovascular and neurological function by addressing the underlying causes of FRDA and associated symptoms.  Agilis also has an option to advance a second undisclosed rare disease indication.

"We are thrilled to be working with Intrexon with the hope of providing children and adults affected with rare genetic disorders with promising new treatments," said George S. Zorich, Chief Executive Officer of Agilis Biotherapeutics.  "We believe Agilis is on the forefront of one of the most promising treatment breakthroughs for Friedreich's ataxia. I am personally excited to collaborate with the Intrexon team and look forward to developing new transformative therapies together."

Samuel Broder, M.D., Senior Vice President of Intrexon's Health Sector and former Director of the National Cancer Institute, said, "FRDA causes heart failure and progressive neurological deterioration, which in turn cause suffering and premature deaths.  The goal of this collaboration is to harness Intrexon's proprietary technologies in synthetic DNA, as well as our expertise in molecular, protein, and cellular engineering, to benefit patients with this very serious disorder." 

Intrexon Founder and Chief Science Officer Thomas Reed, Ph.D., remarked that unlike some biotechnology companies which are limited to single classes of t
'/>"/>

SOURCE Intrexon Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Healthpoint Biotherapeutics to Present at 30th Annual J.P. Morgan Healthcare Conference
2. Oxford BioTherapeutics Appoints C. Glenn Begley as a Senior Clinical Advisor and Non-executive Director
3. Healthpoint Biotherapeutics To Create State-of-the-Art Cell Sciences Manufacturing Facility
4. Northwest Biotherapeutics Appoints Pharma Industry Veteran As CEO Of German Subsidiary
5. Smith & Nephew Announces Agreement To Acquire Assets Of Healthpoint Biotherapeutics
6. Genedata Expressionist for Mass Spectrometry Showcased at 2013 Biotherapeutics Analytical Summit
7. Oxford BioTherapeutics and Boehringer Ingelheim Enter Collaboration to Discover Novel Antibody Targets in Cancer
8. Acquisitions, Project Announcements & Trend Analysis News for Oxygen Biotherapeutics, Glu Mobile, Cisco Systems, Barrick Gold, CVS Caremark
9. Northwest Biotherapeutics Announces Pricing Of Public Offering Of Common Stock And Warrants
10. Northwest Biotherapeutics to Present at the Oppenheimer 24th Annual Healthcare Conference On December 10, 2013
11. Synthetic Biologics and Intrexon Corporation Enter Worldwide Exclusive Collaboration for Infectious Diseases
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/19/2014)... Aug. 19, 2014 Research and Markets  has announced ... Global Strategic Business Report" report to their offering. ... Culture Supplies in US$ Thousands by the following Product Segments: Media, ... for the US, Canada , Japan ... , and Latin America . Annual estimates and ...
(Date:8/19/2014)... 19, 2014 Research and Markets  has announced ... - Global Strategic Business Report" report to their offering. ... Solid Oxide Fuel Cells (SOFCs) in US$ Thousands. The report ... , Europe , Asia-Pacific ... are provided for the period 2012 through 2020. Market data ...
(Date:8/19/2014)... Research and Markets ... "Spectroscopy Equipment and Accessories - Global Strategic ... This report analyzes the ... in US$ Thousands by the following Product ... NMR-EPR Spectrometers, Near Infrared (NIR) Spectrometers, IR ...
(Date:8/19/2014)... Md. , Aug. 19, 2014   ... biotechnology company developing novel anti-infective biologic and drug ... and diseases, announced today that its novel ... at the 54 th Interscience Conference on ... Washington D.C. ...
Breaking Biology Technology:Global Cell and Tissue Culture Supplies - Strategic Business Report 2014 2Global Solid Oxide Fuel Cells (SOFCs) - Strategic Business Report 2014 2Global Spectroscopy Equipment and Accessories - Strategic Business Report 2014 2Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 2Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 3Synthetic Biologics Announces Late-Breaking Poster Presentation for C. difficile Program at 54th ICAAC 4
... Calif., Oct. 12, 2011 Life Technologies ... announced the Applied Biosystems QuantStudio™ 12K Flex ... that enables cost-effective and efficient interrogation of hundreds of ... run. The growing demand of biomarker screening ...
... The National Science Foundation (NSF) has selected a University ... class of NSF Innovation Corps awards. The I-Corps Awards ... and connects scientists to entrepreneurial resources. "The idea ... intellectual property from the lab into the commercial world," ...
... 11, 2011 ThermoGenesis Corp. (NASDAQ: KOOL ... that process and store adult stem cells, said today ... (AXP) which is used to concentrate stem cells from ... & Drug Administration (SFDA) in China. This represents the ...
Cached Biology Technology:Life Technologies Announces Flagship PCR Instrument that Enables Cost-Effective, High-Throughput Screening Applications 2Life Technologies Announces Flagship PCR Instrument that Enables Cost-Effective, High-Throughput Screening Applications 3Life Technologies Announces Flagship PCR Instrument that Enables Cost-Effective, High-Throughput Screening Applications 4Penn team wins entrepreneurial innovation award 2ThermoGenesis Announces Acceptance of AXP® Submission by Regulatory Body in China 2ThermoGenesis Announces Acceptance of AXP® Submission by Regulatory Body in China 3
(Date:8/20/2014)... scientists have discovered that acral melanomas the rare type ... are genetically distinct from other more common types of ... in the journal Pigment Cell & Melanoma Research . ... hands, soles of the feet, nail-beds and other hairless parts ... it,s not caused by UV damage from the sun. , ...
(Date:8/20/2014)... plastic bags could one day be made out of ... are now reporting. The novel process they developed and ... its agricultural and plastic waste problems, appear in the ... S. Bayer and colleagues at the Italian Institute of ... In 2012, its production reached 288 million tons worldwide, ...
(Date:8/20/2014)... 1 (PS1) absorbs light and its energy is ... to biomass. Photovoltaic devices, mostly build from silicon ... electricity. One approach for the development of cheaper ... with the isolated membrane protein complexes of photosynthesis. ... stable PS1 from thermophilic cyanobacteria that live in ...
Breaking Biology News(10 mins):Scientists learn more about rare skin cancer that killed Bob Marley 2A semi-artificial leaf faster than 'natural' photosynthesis 2
... Journal of Experimental Biology are pleased to announce ... is the winner of this year,s JEB Outstanding Paper ... in The Journal of Experimental Biology at ... of an outstanding young scientist to an exceptional research ...
... A new and insidious environmental threat has been ... Queen,s and York universities. Along with scientists ... documented biological damage caused by declining levels of ... the phenomenon "aquatic osteoporosis," Queen,s PhD candidate Adam ...
... Cameroon, and other partners have collaborated to create a ... endangered great ape: the Cross River gorilla. The ... area with Nigeria,s Cross River National Park, safeguarding an ... populationalong with other rare species. Trans-boundary protected areas allow ...
Cached Biology News:French scientist wins the Journal of Experimental Biology Outstanding Paper Prize 2French scientist wins the Journal of Experimental Biology Outstanding Paper Prize 3Queen's University biologists find new environmental threat in North American lakes 2New national park protects world's rarest gorilla 2New national park protects world's rarest gorilla 3
4',6-Diamidino-2-phenylindole dihydrochloride...
...
Normal Bovine Serum; U.S. sourced, ideal for those who seek an uncompromising quality. Low Hemoglobin levels; U.S. sourced, ideal for those who seek an uncompromising quality. Low Hemoglobin lev...
12(S)-HETE-d8 is used as an internal standard for the quantification of 12(S)-HETE by stable isotope dilution mass spectrometry....
Biology Products: