Navigation Links
Affitech Announces Second Milestone in Roche Antibody Discovery Collaboration
Date:9/23/2008

OSLO, September 23 /PRNewswire/ -- Affitech AS, the Norwegian human antibody therapeutics company, today announced that it has accomplished the second milestone in its research and licensing collaboration with Roche to produce fully human recombinant antibodies against an unnamed oncology target. Affitech has successfully used its MBAS (Molecule Based Antibody Screening) system that included its proprietary antibody library and high throughput screening technology to identify several fully human lead antibody candidates. These were then subjected to further engineering in order to generate final candidates that met Roche's various predetermined success criteria. This accomplishment triggered a milestone payment of an undisclosed amount from Roche to Affitech.

"This was a particularly challenging target that Roche asked us to investigate and we are delighted to have delivered a selected group of antibodies, on schedule, that meet their exacting criteria," commented Martin Welschof, Ph.D., Chief Executive Officer of Affitech.

Affitech and Roche entered into this collaboration in 2007 for Affitech to identify and engineer fully human recombinant antibodies against one of Roche's oncology targets. Under the terms of the agreement Roche will now utilize these antibodies for further preclinical evaluation with exclusive rights to develop and commercialize resulting antibodies. Affitech would receive additional milestone payments upon successful development by Roche of these antibodies in oncology or other indications and royalties on worldwide net sales of any successfully developed product candidates.

Notes to Editors:

About Affitech

Affitech AS is a privately held human therapeutic antibody discovery and development company with headquarters and R&D facilities in Oslo, Norway and its US subsidiary in the San Francisco Bay Area. The Company's current disease focus is oncology and it utilizes two discrete but unique approaches for
'/>"/>

SOURCE Affitech AS
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2

Related biology technology :

1. Affitech Appoints Dr. Keith McCullagh as Chairman
2. Affitech and Omeros Enter Into Antibody Discovery and Development Agreement
3. BioMS Medical announces receipt of milestone payment from Eli Lilly and Company
4. Emisphere Announces Recruitment Phase III Study for Oral Osteoarthritis Treatment
5. China-Biotics, Inc. Announces Results of 2008 Annual General Meeting of Shareholders
6. BioElectronics Corp. Announces $400,000 in New Orders From the Middle East
7. The Michigan Life Sciences Pipeline Announces New Best Practices Seminars Tailored to Michigan Businesses
8. Enigma Diagnostics Announces an Award of GBP 1.8 Million From UK Government
9. Oncothyreon announces receipt of NASDAQ letter regarding compliance with NASDAQ Global Market listing standards
10. Quark Pharmaceuticals Announces Poster Presentations at RNAi Europe 2008
11. Dendreon Announces Webcast Presentation at UBS Global Life Sciences Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... 2014  An entire month is dedicated to one ... Charcot-Marie-Tooth disease (CMT) – a debilitating neuromuscular disease affecting ... atrophy, weakness, and foot and hand deformities. CMT affects ... CMT is a progressive disease, and over time patients ... devices such as leg braces, wheelchairs and scooters to ...
(Date:9/19/2014)... , September 19, 2014 BioTech ... developments, patents and results of studies and trials.  Companies ... and Company (NYSE: LLY ), Gilead Sciences ... CELG ) and Arena Pharmaceuticals Inc. (NASDAQ: ... in developing prodrug therapeutics for the treatment of cancer, ...
(Date:9/19/2014)... 2014 , The first grants ... Paediatric Endocrinology (ESPE) Meeting  Investment supports innovative ... in the field of growth  , EMD ... Germany , today announced the first recipients of ... awards were announced during a Satellite Symposium organized by ...
(Date:9/18/2014)... , Sept. 18, 2014 About ... testing, is performed outside a clinical laboratory. It ... in administrating appropriate treatments and medication. POCT is ... prevalence of lifestyle diseases such as diabetes, heart ... user-friendly. POCT devices are standardized to minimize errors ...
Breaking Biology Technology:September is Charcot-Marie-Tooth (CMT) Awareness Month - Scheduled events, activities and important partnerships announced throughout the month! 2Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 2Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 3Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 4Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 5Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 6Biotech Companies Pushing Sector Higher With Recent Therapeutic Advancements & Patent Approvals - Company Wins Summary Judgment For Prodrug Patent 7EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 2EMD Serono Awards Grant for Growth Innovation (GGI) for the First Time 3POCT Market in China 2014-2018 2
... MA , July 21 /PRNewswire-FirstCall/ - SemBioSys Genetics ... proteins and oils utilizing its novel plant expression systems, today ... as President of US and International Operations. Mr. Pierce will ... will offer the Company a broader market to better exploit ...
... July 20 Caliper Life Sciences, Inc. (Nasdaq: CALP ... financial results at 9:00 a.m. ET on Tuesday, August ... McAree , Chief Financial Officer, will host the call. Management will discuss ... , , , ...
... EXTON, Pa. , July 20 Fibrocell Science, Inc. ... autologous cell therapies for aesthetic, medical and scientific applications, announced today that ... its board of directors. , , ... Dr. Korkos currently serves as President of both Plastic Surgery Associates and ...
Cached Biology Technology:SemBioSys Appoints President of US and International Operations and Announces the Appointments of Three Vice Presidents 2SemBioSys Appoints President of US and International Operations and Announces the Appointments of Three Vice Presidents 3SemBioSys Appoints President of US and International Operations and Announces the Appointments of Three Vice Presidents 4Caliper Life Sciences' Second Quarter 2010 Financial Results Conference Call Notice 2Fibrocell Science, Inc. Announces Addition of Dr. George J. Korkos to Board of Directors 2Fibrocell Science, Inc. Announces Addition of Dr. George J. Korkos to Board of Directors 3
(Date:9/18/2014)... stressed they are often grouchy, grumpy, nasty, distracted or ... EPFL have just highlighted a fundamental synaptic mechanism that ... of social skills and cognitive impairment. When triggered by ... the brain. This was revealed by a work published ... team went to look for answers in a region ...
(Date:9/18/2014)... research has found clownfish larvae can swim up to 400 ... able to cope with environmental change. , Clownfish spend their ... but as babies they must wander the open ocean, says ... Excellence for Coral Reef Studies (Coral CoE) at James Cook ... go, but now we,ve been given a rare glimpse into ...
(Date:9/17/2014)... creation of the Santa Ana Wildfire Threat Index ... of the powerful, hot, dry Santa Ana wind, which ... was introduced Sept. 17 by the U.S. Forest Service, ... Electric. , The index includes four classification levels ranging ... help fire agencies and other emergency responders, the media ...
Breaking Biology News(10 mins):How stress tears us apart 2Nemo's epic journey to find a new home 2UCLA scientists play key role in developing new Santa Ana Wildfire Threat Index 2
... Norwich scientists are on the trail of some of the ... targets are the parasitic water fungus that causes powdery mildew ... and tomatoes and downy mildew in cruciferous vegetables and other ... for a while," said Professor Sophien Kamoun, head of the ...
... original sweetener, manufactured by honey bees long before humans ... gatherers, as do ancient Egyptian reliefs. From Mesopotamia to ... every human culture and cuisine. "Honey is fascinating; ... unbelievable activity. It,s just an amazing substance," said University ...
... how a network of repair proteins enables bacteria to prioritise ... DNA molecules that carry the instructions necessary for living cells ... the University of Bristol and published in Molecular Cell ... the DNA repair systems of bacteria and humans than had ...
Cached Biology News:Gene hunters tackle crop diseases 22 books explore the history and delights of honey, bees and beehives 22 books explore the history and delights of honey, bees and beehives 32 books explore the history and delights of honey, bees and beehives 4New research reveals details of microbe's extraordinary maintenance and repair system 2
...
... deuterium atoms at the 9, 10, 12, and ... an internal standard for the quantification of 13(S)-HODE ... by incubation of linoleic acid with plant and ... the adhesion of tumor cells to the endothelium ...
... Cells and TriEx Insect Cell Medium are ... constructs. This cell/medium combination has been selected ... high protein expression levels observed specifically with ... note that our Ready-Plaque Sf9 Cells and ...
...
Biology Products: