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Aeterna Zentaris Reports First Quarter 2010 Financial and Operating Results
Date:5/13/2010

All amounts are in U.S. dollars

QUEBEC CITY, May 13 /PRNewswire-FirstCall/ - Aeterna Zentaris Inc. ( AEZS, TSX: AEZ) ("the Company"), a late-stage drug development company specialized in oncology and endocrinology, today reported financial and operating results as at and for the three months ended March 31, 2010.

First Quarter 2010 Highlights

    - January 25, 2010: Updated results of a Phase 2 study related to the use
      of perifosine in the treatment of advanced metastatic colon cancer
      showing a statistically significant benefit in survival, including
      5 FU-refractory patients.

    - January 29, 2010: Publication in the February 2010 issue of the Journal
      of Clinical Cancer Research of positive Phase 2 results for perifosine
      as a single agent for the treatment of advanced Waldenstrom's
      macroglobulinemia.

    - February 3, 2010: Special Protocol Assessment ("SPA") granted by the
      United States Food and Drug Administration ("FDA") for the Phase 3
      trial of perifosine in combination with capecitabine (Xeloda(R)) in
      refractory advanced colorectal cancer. The trial is to be conducted by
      Keryx Biopharmaceuticals, Inc. ("Keryx") ( KERX), Aeterna
      Zentaris' partner and licensee for perifosine in North America.

    - March 1, 2010: Disclosure that the Committee for Orphan Medicinal
      Products of the European Medicines Agency ("EMA") had issued a positive
      opinion for orphan medicinal product designation for perifosine for the
      treatment of multiple myeloma.

Subsequent to Quarter-End

    - April 5, 2010: Perifosine receives FDA Fast Track Designation for the
      Phase 3 X-PECT (Xeloda(R) + Perifosine Evaluation in Colorectal cancer
      Treatment) registration trial.

    - April 8, 2010: Initiation 
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SOURCE AETERNA ZENTARIS INC.
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Related biology technology :

1. Aeterna Zentaris: FDA Approves Investigational New Drug (IND) Application for Doxorubicin Targeted Conjugate Compound, AEZS-108, in Bladder Cancer
2. Aeterna Zentaris Receives Orphan-Drug Designation from the FDA for AEZS-108 in Ovarian Cancer
3. AEterna Zentaris Announces Termination of Agreement with sanofi-aventis U.S. for the Development, Commercialization and Licensing of Cetrorelix in Benign Prostatic Hyperplasia
4. AEterna Zentaris Partner, Keryx, Initiates Phase 3 Registration Trial with Perifosine (KRX-0401) for the Treatment of Patients with Advanced Multiple Myeloma
5. AEterna Zentaris Announces Appointment of New Board Member
6. AEterna Zentaris Partner, Keryx, Reports Updated Phase 1/2 Data, Including New Survival Data, on Perifosine (KRX-0401) in the Treatment of Advanced Multiple Myeloma at the 51st Annual Meeting of the American Society of Hematology
7. AEterna Zentaris Announces Results from its European Phase 3 Study with Cetrorelix in Benign Prostatic Hyperplasia
8. AEterna Zentaris Anti-Cancer Compound, Perifosine (KRX-0401), Receives FDA Fast Track Designation for the Treatment of Relapsed/Refractory Multiple Myeloma
9. AEterna Zentaris Announces Positive Results for Phase 2 Study with LHRH-Receptor Targeted Cytotoxic Conjugate AEZS-108 in Endometrial Cancer
10. AEterna Zentaris Receives US$5.5 Million from Institutional Investors
11. AEterna Zentaris to Raise US$5.5 Million from Institutional Investors at US$1.20 Per Share
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