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Advanced Life Sciences Awarded U.S. Department of Defense Biodefense Contract Valued at up to $3.8 Million
Date:8/13/2008

omycin against Burkholderia pseudomallei shows that it is very active and may have a more favorable resistance profile than other approved antibiotics in treating melioidosis." Dr. Schweizer added, "This government funding from DTRA for the advanced development of cethromycin to treat bioterror pathogens serves as a critical step that may result in advances for both national security and public health."

Under the terms of the contract, $1.8 million of DTRA funds are available over a nine-month base period to initiate NDA-enabling studies measuring cethromycin's efficacy in treating tularemia and plague as well as studies to measure cethromycin's efficacy in treating melioidosis. The remaining $2.0 million may be awarded over the ensuing 15 months to complete the project.

Dr. Michael Flavin went on to say, "The U.S. Government is committed to identifying and acquiring a next-generation antibiotic that has activity against more that one Category A and B bioterror pathogen. If cethromycin can demonstrate potent activity through the studies funded by this contract, we believe it will be well positioned to compete for revenues from a potential stockpile contract."

About the Defense Threat Reduction Agency

The Defense Threat Reduction Agency (DTRA) is the intellectual, technical and operational leader for the Department of Defense (DoD) and the U.S. Strategic Command in the national effort to combat the weapons of mass destruction (WMD) threat. Under DTRA, DoD resources, expertise and capabilities are combined to ensure the United States remains ready and able to address the present and future WMD threat. DTRA performs four essential functions to accomplish its mission: combat support, technology development, threat control and threat reduction. These functions form the basis for how it is organized and its daily activities.

About Cethromycin

Cethromycin is a novel once-a-day oral antibiotic in late-stage development for the treat
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SOURCE Advanced Life Sciences Holdings, Inc.
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