Navigation Links
Advanced Life Sciences Announces Successful Preclinical Data Supporting Restanza Intravenous Formulation for Hospital Use
Date:7/8/2010

tch as the patient moves from an in-patient setting to an outpatient setting. This is a significant feature that enhances the overall Restanza value proposition for physicians and patients."

Urgent Market Need for Potent Hospital-Based IV Antibiotics

There is an urgent market need in the U.S. and worldwide to identify and rapidly develop novel, safe and effective antibiotics that can overcome resistance to currently available drugs and that can be used in a variety of settings, such as an IV treatment in the hospital, and an IV-to-pill switch for stabilized patients and an oral treatment for outpatients.

Ketolide antibiotics, which represent a newer and promising class of therapeutics with greater potential against bacterial strains that are resistant to macrolides and penicillins, are typically very difficult to formulate in a clinically viable IV formulation due to low water solubility. Advanced Life Sciences has achieved a major breakthrough by successfully developing an IV formulation of Restanza.  The formulation can be stored in a stable powder form and reconstituted on site in the hospital. The key features of this formulation support developing Restanza IV for use in the hospital setting.

The next step in the program is to initiate additional IND-directed preclinical studies of the Restanza IV formulation to support future Phase I clinical trials in normal healthy volunteers to evaluate its safety and pharmacokinetics.

About Restanza

Restanza is a novel oral once-a-day antibiotic that is in late stage development for the treatment of community acquired bacterial pneumonia and biodefense pathogens such as anthrax. It has shown higher in vitro potency and a broader range of activity than macrolides against Gram-positive bacteria including
'/>"/>

SOURCE Advanced Life Sciences Holdings, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Advanced Life Sciences Awarded U.S. Department of Defense Biodefense Contract Valued at up to $3.8 Million
2. Advanced Life Sciences Announces Second Quarter 2008 Financial Results
3. LUMEDX Introduces Advanced Multi-Modality, Multi-Vendor, Web-Enabled ECG Management Solution
4. Waters Brings Advanced Laboratory Data Management to Microsofts BioIT Alliance
5. Orange Coast Urology Offers Advanced In-Office Patient EVOLVE(R) Laser Prostate Treatment
6. Advanced Pest Control Earns Quality Pro Designation for General Pest Control Services
7. Independent Monitoring Board Recommends Completion of Accrual to Genasense(R) Phase 3 AGENDA Trial in Advanced Melanoma
8. Advanced Chemical Transport Opens Merced Facility
9. Advanced Life Sciences to Host Conference Call to Update Investors on Progress of Corporate Initiatives on October 1, 2008
10. Advanced Instruments Acquires D & F Control Systems Inc.
11. DuPont Meeting Significant 2008 Milestones in Progressing Advanced Biofuels
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... , Sept. 19, 2014 Pfenex Inc. (NYSE ... development of high-value and difficult to manufacture proteins including ... at the 21 st Annual NewsMakers in the ... . Bertrand Liang , chief executive officer of ... programs and business strategy on Friday, September 26, 2014 ...
(Date:9/19/2014)... Barnhardt Manufacturing Company has earned the ... Cotton . The USDA Certified Biobased Product Label verifies ... or exceeds levels set by USDA. Biobased products are ... significant part of agricultural, forestry, or marine ingredients. ... be immediately identified as a USDA certified BioPreferred ...
(Date:9/19/2014)... 2014 Dublin ... has announced the addition of the  "Micro Market ... their offering.       (Logo: http://photos.prnewswire.com/prnh/20130307/600769) , ... the fastest-growing segments in the chromatography market. The ... and expected to reach $2.0 billion by 2019, ...
(Date:9/19/2014)... The new , Healthcare and Life ... today on PharmaBoardroom.com for free download , ... the Spanish economy in 2009, and the austerity measures that ... pragmatic in times of trouble. "Despite the crisis, ... European market, and the general conditions to invest are favorable ...
Breaking Biology Technology:Pfenex to Present at Upcoming Industry Conference on September 26 2Barnhardt Manufacturing Company Earns USDA Certified Biobased Product Certification and Label for Organic Cotton 2Micro Market Monitor : Global Pre-packed Chromatography Columns 2PharmaBoardroom Releases New Spain Pharmaceuticals Report 2PharmaBoardroom Releases New Spain Pharmaceuticals Report 3
... April 24 CardioVascular,BioTherapeutics, Inc. (OTC Bulletin Board: CVBTE) ... to form Cardio Derma Clinical Partners,(CDCP), an R&D Partnership. ... minimum of $1,000,000 and up to $5,000,000 of the ... Partnerships have been successfully used in the past by ...
... Amicus Therapeutics,Inc. (Nasdaq: FOLD ), today announced that ... a corporate update at the Morgan,Stanley Global Healthcare Unplugged ... at the Ritz-Carlton in Key Biscayne, Florida., The ... by visiting,Amicus, website at http://www.amicustherapeutics.com . A replay ...
... Two 4-week cohorts will be enrolled to evaluate R7128 1500mg BID in HCV,genotypes 2 ... ... 25, 2008 at 1:00 PM ET (US) ... and 7:00 PM CEST (Milan) --, PRINCETON, N.J. and MILAN, Italy, April 24 ...
Cached Biology Technology:CardioVascular BioTherapeutics, Inc. Funding Wound Healing Trial with R&D Partnership 2CardioVascular BioTherapeutics, Inc. Funding Wound Healing Trial with R&D Partnership 3Pharmasset Adds Two Cohorts to R7128 Hepatitis C Study 2Pharmasset Adds Two Cohorts to R7128 Hepatitis C Study 3Pharmasset Adds Two Cohorts to R7128 Hepatitis C Study 4Pharmasset Adds Two Cohorts to R7128 Hepatitis C Study 5
(Date:9/18/2014)... icy moon of Uranus, is one of the most ... Despite its relatively small size, Miranda appears to have ... the formation of at least three remarkable and unique ... These coronae are visible in Miranda,s southern hemisphere, and ... corona, the largest, has ridges and troughs with up ...
(Date:9/18/2014)... University and the Quebec government have discovered microplastics ... Journal of Fisheries and Aquatic Sciences . , ... or industrial cleansers, to which they are commonly ... and buoyancy, they may readily pass through sewage ... in the world,s oceans, but have only recently ...
(Date:9/18/2014)... to undertake jaunts into the countryside each year could come ... century, according to new research. , Climate change could postpone ... as summer temperatures linger later into the year, Princeton University ... . For instance, the paper birch a popular foliage ... could change color one to three weeks later by the ...
Breaking Biology News(10 mins):Miranda: An icy moon deformed by tidal heating 2Miranda: An icy moon deformed by tidal heating 3Miranda: An icy moon deformed by tidal heating 4Miranda: An icy moon deformed by tidal heating 5Miranda: An icy moon deformed by tidal heating 6Miranda: An icy moon deformed by tidal heating 7Microplastic pollution discovered in St. Lawrence River sediments 2Fall foliage season may be later, but longer on warmer Earth 2Fall foliage season may be later, but longer on warmer Earth 3Fall foliage season may be later, but longer on warmer Earth 4
... Along with pollutants from Asia, transpacific dust plumes deliver ... a manuscript published online ahead of print in the ... "We detected thousands of unique microbial species, many of ... author David J. Smith, a graduate student at the ...
... and climate warming could be creating the right conditions for ... a new Cornell University computer model., The model predicts that ... spread by the invasive Asian tiger mosquito, could occur in ... Atlanta from June through September, and year-round in Miami. The ...
... with Down syndrome (DS) suffer from marked muscle weakness. Even the ... chair or climbing a flight of stairs, can become major obstacles. ... and lead to a loss of independence. Now, a new study ... Led by scientists from Syracuse University, a research team ...
Cached Biology News:Dust-plumes power intercontinental microbial migrations 2Chances seen rising for chikungunya outbreaks in NYC, Atlanta, Miami 2Study offers insights into role of muscle weakness in Down syndrome 2Study offers insights into role of muscle weakness in Down syndrome 3
... Duo is suitable for use with a ... solvents through to water and some of ... concentrator capable of removing water and organic ... including tubes, microplates, vials and round bottom ...
... Precision Model 410 is a four-channel general purpose ... small signals from sources which may have a ... channel consists of a high gain/low noise amplifier, ... and an output offset control. A control knob ...
Proliferin (N-14)...
Porcine Aortic Smooth Muscle Cells (PAOSMC) (>500,000 cells)...
Biology Products: