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Advanced Life Sciences Announces Second Quarter 2008 Financial Results
Date:8/14/2008

Present posters and meet with National Advisory Board for

cethromycin at the October 25-28 ICAAC/IDSA conference in

Washington, DC;

* Under the DTRA contract, expand advanced studies of cethromycin as a

broad spectrum medical countermeasure;

* Continue preparing for commercial launch of cethromycin through

manufacturing, market research, medical education, and pricing

strategy activities;

* Dose first patient in ALS-357 PhaseI/II melanoma trial.

Financial Guidance for the Third Quarter of 2008

Advanced Life Sciences expects its third quarter 2008 cash requirements to fall in the range of $3.4 million and $3.7 million, leaving a cash balance of $5.4 million to $5.7 million as of September 30, 2008. Management believes that this cash balance will be sufficient to allow the Company to progress to the period in which it submits the NDA for cethromycin in the CAP indication to the FDA. To fund ongoing operations including the payment of any milestone payment due to Abbott Laboratories in connection with the submission of the cethromycin NDA, the Company intends to raise additional capital in 2008 through a commercial partnership and/or the sale of equity, if available at terms acceptable to us, which cannot be assured.

Conference Call Details

Advanced Life Sciences will host a conference call and live webcast at 10:00 a.m. Eastern Time on Thursday, August 14, 2008 to discuss the company's second quarter financial results.

The conference call will be webcast simultaneously over the Internet. Please visit the Investor Relations section of the Advanced Life Sciences corporate website http://www.advancedlifesciences.com. Alternatively, callers may participate in the conference call by dialing 888-713-4218 (domestic) or 617-213-4870 (international). The passcode for the conference call is
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SOURCE Advanced Life Sciences Holdings, Inc.
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