Malaria is a parasitic disease that is characterized by high fevers, shaking chills, flu-like symptoms, and anemia, and requires hospitalization. Malaria is typically caused by a parasite that is transmitted from one human to another by the bite of infected mosquitoes. Malaria can also be transmitted from a mother to her unborn baby and by blood transfusions. In humans, the parasites (sporozoites) travel to the liver where they mature and release another form, the merosoites, which enter the bloodstream and infect red blood cells. The parasites multiply inside the red blood cells, which then rupture within 48 to 72 hours, infecting more red blood cells. The first symptoms usually occur 10 days to four weeks after infection, though they can appear as early as eight days or as long as a year after infection.
Malaria is a serious health problem in much of the tropics and subtropics and represents a major disease hazard for travelers to these regions and other warm climates. The widespread prevalence of malaria in Africa poses a severe social and economic threat. The Centers for Disease Control and Prevention (CDC) estimates that there are 300-500 million cases of malaria each year, resulting in more than one million deaths, many among very young children. Conventional treatment includes chloroquine, quinidine or quinine. In some areas of the world, the parasites have developed resistance to antibiotic treatments (doxycycline, tetracycline or clindamycin, atovaquone plus proguanil, mefloquine or artesunate, or the combination of pyrimethamine and sulfaxcozine). This has led to difficulty in controlling both the rate of infection and spread of this dis
|SOURCE Advanced Life Sciences Holdings, Inc.|
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