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Advanced Cell Diagnostics Completes $12 Million Series B Financing
Date:11/1/2012

first automated multiplex in situ hybridization platform capable of detecting and quantifying RNA biomarkers in situ at single-molecule sensitivity. Traditionally, RNA biomarkers are analyzed by "grind-and-bind" assays such as RT-PCR, which lose cellular context critical for clinical interpretation. RNAscope provides single-cell gene expression information within full cellular and tissue context and is compatible with routine clinical specimen and standard clinical laboratory workflow.  Unlike antibodies which are available for only a small fraction of the human proteome and not suitable for the emerging class of non-coding RNAs, RNAscope assays can be developed within two weeks for virtually any gene in the human genome regardless of its coding potential. Currently, ACD offers RNAscope-based products and services worldwide to scientists in a broad range of research areas from basic research to companion diagnostics for personalized medicine. Customers include many world-renowned academic institutions and all major pharmaceutical/biotech companies.  

About Advanced Cell Diagnostics
Advanced Cell Diagnostics, Inc. (ACD) is a leader in the emerging field of molecular pathology, developing cell- and tissue-based diagnostic tests for personalized medicine. The company's products and services are based on its proprietary RNAscope® technology, the first multiplex fluorescent and chromogenic in situ hybridization platform capable of detecting and quantifying RNA biomarkers in situ at single-molecule sensitivity. ACD partners with pharmaceutical and biotechnology companies to validate biomarkers for targeted therapeutic development in cancer and other diseases. These partnerships provide the foundation for ACD to develop companion diagnostic tests in conjunction with partners' targeted therapeutics. ACD also pursues internal programs to develop proprietary diagnostic tests in cancer management. Learn more about ACD and RNAscope technology at
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