Navigation Links
Adheron Therapeutics Names New Senior Leadership

SAN FRANCISCO, Sept. 11, 2013 /PRNewswire/ -- Adheron Therapeutics, a biotechnology company that is focused on leveraging pioneering technology that disrupts cell adhesion to treat a variety of diseases, has announced the appointments of Robert Baltera as executive chairman of the board and Hari Kumar as chief executive officer, effective immediately.

Baltera and Kumar served most recently as senior officers of Amira Pharmaceuticals, which was acquired by Bristol Myers Squibb for $325M upfront and $150M in milestones. At Adheron Therapeutics - previously known as Synovex Corporation – Baltera and Kumar's focus will be developing the company's novel Cadherin-11 technology for various therapeutic indications.

"I am very excited about my new role at Adheron Therapeutics. I am deeply impressed by the innovative technology that we are developing and I look forward to advancing it to the next level," said Kumar.

The company's therapeutic program is based on pioneering work completed in the laboratory of Michael Brenner, MD, at Brigham and Women's Hospital and Harvard Medical School. Prof. Brenner discovered that the protein Cadherin-11 (Cad-11) acts as an "adhesive" between cells, and that changes in Cad-11 interactions can induce cells to produce proteins that influence the cellular environment positively or adversely. Further research by Dr. Brenner confirmed that Cad-11 acts as a key mediator of joint destruction in rheumatoid arthritis, and is also an important contributor to pulmonary and skin fibrosis pathology. 

Baltera added: "Cadherin-11 is a very promising technology, which I am confident will be applied in various areas of high unmet medical need. I am pleased to lead Adheron and I am confident we will see exciting results."

Based on Dr. Brenner's research, Adheron Therapeutics has developed an antibody that inhibits Cad-11. The company, which Dr. Brenner and Dr. David Lee established in 2006 as Synovex Corporation, plans to evaluate the benefits of this antibody in multiple therapeutic areas including cancer, rheumatoid arthritis and fibrosis, and advance it through clinical proof of concept. Adheron has just completed a Phase I single ascending-dose study for its lead asset, the Cad-11 inhibitor SDP051. 

Adheron Therapeutics is funded by Health Care Ventures, MedImmune Ventures, Partners Innovation Fund, Amgen Ventures, and SROne.

About CAD 11
Cadherin-11 (Cad-11) is a surface protein expressed on fibroblasts in the skin and lungs, and fibroblast-like synoviocytes (FLS) in the joints. Cad-11 acts as an "adhesive" between cells, and changes in Cad-11 interactions can induce the cells to produce proteins that influence the cellular environment positively or adversely. Research completed in the laboratory of Michael Brenner, MD, at Brigham and Women's Hospital and Harvard Medical School has implicated Cad-11 in the disease processes leading to rheumatoid arthritis. Work initiated in Dr. Brenner's laboratory by Dr. Sandeep Agarwal, now at Baylor College of Medicine, has also demonstrated that Cad-11 plays a role in diverse fibrotic diseases.

About Adheron Therapeutics
Adheron Therapeutics is a biotechnology company focused on leveraging pioneering technology that disrupts cell adhesion to treat a variety of diseases. Founded by Dr. Brenner and Dr. Lee of Harvard Medical School, the company is led by industry veterans Bob Baltera (executive chairman) and Hari Kumar, PhD (CEO), and funded by a group of venture investors comprising Health Care Ventures, MedImmune Ventures, Partners Investment Fund, Amgen Ventures, and SROne.

Jacqueline Wallach
650 283 6617

Michele Parisi
925 429 1850

SOURCE Adheron Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. Case Report Suggests Microbiome Therapeutics NM504 May Improve Tolerability of Metformin While Improving Blood Glucose Control
2. Echo Therapeutics Sends Response to Shareholder Letter
3. Convoy Therapeutics to Present at 2013 Rocky Mountain Life Science Investor and Partnering Conference
4. Orexigen Therapeutics Prepares for the Light Study Interim Analysis Based on Direction from Data Monitoring Committee
5. Technical Study: Vertex Pharma Inc., Orexigen Therapeutics Inc., MAKO Surgical Corp., and Alere Inc.
6. AML Therapeutics Market in the 6MM Worth $430.7m in 2017 Says a New Research Report Available at
7. Global Lung Cancer Therapeutics Market 2013 Report Featuring Leading Players Such As AstraZeneca, Bristol-Myers Squibb, Eli Lilly and Co., GlaxoSmithKline, Hoffmann-La Roche, Novartis And Others
8. Oncology Therapeutics Market in India to 2018 Report
9. PTC Therapeutics Announces Achievement Of Major Milestone In SMA Collaboration
10. NuMe Health Becomes MicroBiome Therapeutics And Recruits New CEO
11. Enteris BioPharma Initiates Business and Development Activities Targeting Oral Delivery of Peptides and Small Molecule Therapeutics
Post Your Comments:
(Date:12/1/2015)... DUBLIN , December 1, 2015 /PRNewswire/ ... the addition of the  "2016 U.K. Virology ... Segment Forecasts for 100 Tests, Supplier Shares ... Opportunities"  report to their offering.  --> ... of the  "2016 U.K. Virology and Bacteriology ...
(Date:11/30/2015)... ... November 30, 2015 , ... Global Stem Cells Group announced that ... closed system for isolating adipose-derived stem cells. The announcement starts a new phase toward ... SVF is a component of the lipoaspirate obtained from liposuction of excess adipose tissue. ...
(Date:11/30/2015)... ... ... Cells Group announced the opening of a new core patient care hub with the ... The facilities are part of GSCG’s expansion efforts in Latin America. , Both the ... to patients from around the world. , The clinics will be headed by Victor Perez, ...
(Date:11/30/2015)... Dec. 1, 2015 /PRNewswire/ - BioAmber Inc. (NYSE: BIOA ), ... joined the American Business Act on Climate Pledge, alongside more ... standing with the Obama Administration to demonstrate an ongoing commitment ... outcome to the COP21 Paris climate ... Sarnia, Canada . --> BioAmber ...
Breaking Biology Technology:
(Date:11/30/2015)... DEERFIELD BEACH, Fla. , Nov. 30, 2015 ... selected as a finalist in this year,s Fierce Innovation ... publisher of FierceHealthIT , ... BIOCLAIM was recognized as a finalist in the ... --> ...
(Date:11/18/2015)... -- As new scientific discoveries deepen our understanding of how ... face challenges in better using that knowledge to guide ... more children continue to survive pediatric cancer, that counseling ... John M. Maris, M.D ., a pediatric ... . --> John M. Maris, M.D ...
(Date:11/17/2015)... Mass. , Nov. 17, 2015 Pressure ... leader in the development and sale of broadly enabling, ... worldwide life sciences industry, today announced it has received ... its $5 million Private Placement (the "Offering"), increasing the ... $4,025,000.  One or more additional closings are expected in ...
Breaking Biology News(10 mins):