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Adaptive TCR Launches the immunoSEQ™ Product Line - Visualizing the Immune System With Next-Generation Sequencing.
Date:10/20/2010

SEATTLE, Oct. 20 /PRNewswire/ -- Adaptive TCR Technologies, a biotech firm based in Seattle, WA, announced today the release of its immunoSEQ™ profiling service and immunoSEQ Analyzer™ bioinformatics software platform.  Together, these tools provide researchers and clinicians the ability to profile and monitor the adaptive immune system at a level of detail that has never before been possible.

"ImmunoSEQ represents one of the first specific applications of next-generation sequencing technology," offers Chad Robins, CEO and Founder of Adaptive TCR. "We have delivered the Hubble Telescope as compared to a pair of binoculars to look at the adaptive immune system."

ImmunoSEQ assays use proprietary chemistry to amplify the rearranged CDR3 regions of T-cell receptor (TCR) genes responsible for most TCR diversity.  Each immunoSEQ assay can generate millions of cell-specific sequences, allowing a remarkably deep characterization of the T-cell repertoire in any sample.  To analyze this large amount of data, Adaptive TCR provides access to the immunoSEQ Analyzer, a bioinformatics software platform comprising a suite of tools designed specifically to handle immunoSEQ data.  

"Using DNA sequencing to look at cells of the immune system is particularly powerful," said Dr. Harlan Robins, a computational biologist at the Fred Hutchinson Cancer Research Center and co- founder of Adaptive TCR. "By bringing together unique amplification chemistries, massively parallel sequencing and powerful, user-friendly software, we are providing access to the adaptive immune system in unbelievable detail."  

In addition to providing information on the basic functioning of the immune system, immunoSEQ data can contribute to the understanding and development of many important medical conditions and applications, including cancer immunotherapy, autoimmune disorders, vaccine development, and infectious disease.  "We know
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SOURCE Adaptive TCR Corporation
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