Navigation Links
Adaptive Biotechnologies Receives $2.53 million Phase II SBIR to Develop Test to Identify Cancer Patients at Risk of Death by Infection after Cord Blood Transplants
Date:9/13/2013

eration Sequencing platform, immunoSEQ™, will be used in the phase II study to measure T-cell and B-cell diversity. The study will be conducted prospectively over a three-year period on approximately 400 cord blood transplant recipients from five of the top transplant centers in the United States. Patients' blood will be drawn at several time points after transplant and shipped to Adaptive's CLIA-certified centralized laboratory in Seattle. The company's immunosequencing platform and accompanying bioinformatics tools will be used to calculate a precise measure of diversity for each patient at each time point. While cord blood transplant serves as an ideal model to confirm the importance of immune reconstitution because of the higher incidence of infectious morbidity and mortality compared to other tissue sources used for stem cell transplants, the results should apply to all stem cell transplantation procedures.

This test of immunocompetence will add to Adaptive's portfolio of products that use immunosequencing for prognosis, diagnosis, and monitoring of cancer patients. The company's first clinical application, clonoSEQ™, is for monitoring Minimal Residual Disease ("MRD") in blood-based cancers.

About Adaptive Biotechnologies

Adaptive Biotechnologies Corporation ("Adaptive" or the "Company") is a development stage biotechnology company that utilizes its proprietary immune profiling technology to discover, develop, and commercialize oncology diagnostics. The Company leverages advances in next generation sequencing ("NGS") to profile T-Cell and B-Cell Receptors ("TCRs" and "BCRs").  This breakthrough enables in-depth characterization of the immune system, which is the primary defense against cancer. By incorporating immunosequencing into clinical care, Adaptive can enhance the diagnosis, prognosis, and monitoring of cancer patients. The Company's first clinical
'/>"/>

SOURCE Adaptive Biotechnologies Corporation
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related biology technology :

1. PI Releases High Power Piezo Amplifier to Drive Adaptive Structures, Fast Tool Servos, Vibration Cancellation Systems – Model E-482
2. Adaptive Biotechnologies Signs Biomarker Discovery Collaboration Agreement with Bristol-Myers Squibb
3. Adaptive Biotechnologies launches clonoSEQ, a more sensitive, accurate assay to detect minimal residual disease (MRD) in blood-based cancers.
4. Microvi Biotechnologies Appoints Former COO of Zenon Environmental as Chairman of Board of Directors
5. Dr. Gerald Jerry Zon Launches New Blog for TriLink BioTechnologies
6. TriLink BioTechnologies Announces Worldwide License with QuantiBact A/S, Copenhagen, Denmark
7. TriLink BioTechnologies Awards Keck Science Department ResearchReward
8. OPX Biotechnologies Selected as Innovation Pioneer at IHS CERAWeek
9. Medical Marijuana, Inc. Portfolio Company CanChew BioTechnologies Inc. Updates and Expands Free Product Trial
10. Lifeline Biotechnologies Receives Patent for Methods to Collect and Analyze Breast Thermal Data to Determine Suspect Conditions
11. Leading Scientists to Debate Views on Rejuvenation Biotechnologies
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Village, Calif. (PRWEB) January 15, 2014 ... treatment and management through the genomic analysis of tumor ... offer Therapy Finder™, a web-based cancer decision support application ... reporting option with Cynvenio’s ClearID™ genomic test, Therapy Finder ...
(Date:1/15/2014)... Toronto, Canada (PRWEB) January 15, 2014 ... perspectives on nonclinical and clinical safety assessment in biosimilars. ... a path for biosimilar drug development, however the complex ... regards to quality, safety and efficacy extremely challenging. Based ...
(Date:1/15/2014)... 15, 2014 Two champions of science, ... sponsorship of an annual competition for middle and high ... to, innovative STEM study. The competition presents students with ... of Engineering Aptitude, Mathematics, and Sciences is a ...
(Date:1/15/2014)... 2013 was a banner year of continued ... saw continued independent research led by the team at ... $1 million grant from the Susanne Marcus Collins Foundation, ... peer reviewed journal, Amy Grant highlighted Brainwave Optimization® in ...
Breaking Biology Technology:Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 2Cynvenio Offers New Breast Cancer Therapy Finder Application for its ClearID Breast Cancer Genomic Test 3Xtalks Life Sciences Webinar Examines Safety Assessment of Biosimilars 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 2Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 3Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 4Technology Student Association Partners with Leaders in STEM Education Advocacy for Annual Competition 5Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 2Dynamic Innovative Technology Showcased at Scottsdale Company’s Open House 3
... Inc. (NTI(R)) (Nasdaq: NTII ), today announced ... GmbH (Merz) for sales,by Merz and its marketing ... disease for the quarter ended September 30,2007. Under ... payments on sales of Memantine by Merz and ...
... improved but still flawed government-wide plan for nanotechnology ... system. Federally-funded studies essential to managing possible ... by a top-down strategy tied to projected commercialization, ... decision-making process. , The National Nanotechnology ...
... collaboration between researchers at the National Institute of Standards ... Kentucky potentially offers a low-cost way to mass produce ... for a wide range of applications including flexible displays, ... field diagnostics. , In a paper posted this week,* ...
Cached Biology Technology:Neurobiological Technologies Reports $2.1 Million Quarterly Payment for Sales of Memantine 2Federal nanotech risk research plan still comes up short 2Directed self-ordering of organic molecules for electronic devices 2
(Date:7/9/2014)... common frog is one of the amphibians with the ... in permanent areas of water where it comes into ... its larvae. Research carried out by the Spaniard Germn ... the larvae of these frogs have developed a defensive ... tails and larger bodies if they co-exist with the ...
(Date:7/9/2014)... measurement results accrue. To completely and systematically archive ... In fact, researchers in the life sciences spend ... to an online survey of 70 people working ... for Applied Information Technology FIT in Sankt Augustin. ... no centralized or structured approach to data collection ...
(Date:7/9/2014)... inhibitors and N-methyl-D-aspartate receptor antagonists can alleviate ... to affect irreversible cognitive dysfunction and effectively ... Amyloid beta peptide (Aβ) vaccines reduced and ... (AD) transgenic mouse model, and significantly improved ... and his team, First Affiliated Hospital of ...
Breaking Biology News(10 mins):Frogs have developed rapid defences against the red swamp crayfish 2Frogs have developed rapid defences against the red swamp crayfish 3Managing the data jungle 2Managing the data jungle 3
... of vertebrate species, but while groups such as mammals, birds ... decades, knowledge about relationships among many types of fishes was ... of scientists led by Richard Broughton, associate professor of biology ... of Oklahoma, published two studies that dramatically increase understanding of ...
... proportion of black carbon created during combustion will remain in ... burying black carbon in the ground in order to restrain ... a part of black carbon will dissolve from soil to ... to the ocean was estimated in a research article published ...
... the University of Birmingham, BGI and its open-access ... the UK,s Natural Environment Research Council (NERC) to ... large-scale environmental metabolomics data. Metabolomics involves the ... living organisms and can provide an indication of ...
Cached Biology News:Something's fishy in the tree of life 2'Black carbon' flowing from soil to oceans 2Collaboration to establish new computational resources for metabolomics 2
RABBIT ANTI HUMAN TRRAP (CT) Immunogen: Recombinant C-terminal kinase-related domain of human TRRAP....
RABBIT ANTI HUMAN CHYMOTRYPSIN...
MSE ANTI CAN. CD3:FITC/RAT ANTI CD4:RPE...
MOUSE ANTI POLY (ADP-RIBOSE) Immunogen: Purified poly (ADP-ribose) polymer, 10-50 unit chain length...
Biology Products: