Navigation Links
Actelion Announces Multiple Presentations on Tracleer(R) and the REVEAL Registry at CHEST 2007

CHICAGO, Oct. 19 /PRNewswire/ -- Actelion Ltd (SWX: ATLN) today announced multiple presentations regarding Tracleer(R) (bosentan), including new Phase 3 data assessing the efficacy and safety of Tracleer in combination with sildenafil, and data obtained from the first 1,500 patients with pulmonary arterial hypertension (PAH) enrolled in the REVEAL(TM) (Registry to EValuate Early And Long-term PAH Disease Management) Registry. The presentations and publications are part of the proceedings at CHEST 2007, the annual meeting of the American College of Chest Physicians, being held October 20-25, 2007 at McCormick Place in Chicago, IL. The company will be exhibiting at booth # 239 in the Exhibit Hall.

The presentations and abstracts -- including date and location for each -- are as follows:

Tuesday, October 23, 2007, 12:30 p.m. - 2:00 p.m.

Session: Pulmonary Vascular Disease: Evaluation and Treatment, ID #858

Oral Presentation: REVEAL Registry: Baseline Characteristics of the First

Enrolled Patients

Location: Convention Center E264

Presenter: David Badesch, MD

Abstract #: 5982

Tuesday, October 23, 2007, 2:30 p.m. - 4:00 p.m.

Session: Pulmonary Vascular Disease: Pulmonary HTN, ID # 900

Oral Presentation: Bosentan improves hemodynamics in patients receiving

background Sildenafil treatment: results from EARLY, a randomized,

double-blind, placebo controlled study in patients with mildly

symptomatic pulmonary arterial hypertension

Location: Convention Center E266

Presenter: Lewis Rubin, MD

Abstract #: 5356

Session: Pulmonary Vascular Disease : Pulmonary HTN, ID # 900

Oral Presentation: Acute hemodynamic effect of Sildenafil in comparison

with inhaled nitric oxide in patients receiving Bosentan therapy for

pulmonary arterial hypertension (COMPASS-1)

Location: Convention Center E266

Presenter: Nazzareno Galie, MD

Abstract #: 5482

Wednesday, October 24, 2007, 12:30 p.m. - 2:00 p.m.

Session: Pulmonary Vascular Disease: Pulmonary HTN Evaluation and

Treatment, ID #893

Poster Presentation: REVEAL Registry: Treatment History and Treatment at


Location: Convention Center, Exhibit Hall

Presenter: Michael McGoon, MD

Poster #: 585

Abstract #: 6023

Session: Pulmonary Vascular Disease: Pulmonary HTN Evaluation and

Treatment, ID #893

Poster Presentation: REVEAL Registry: Medical History and Time to

Diagnosis of Enrolled Patients

Location: Convention Center, Exhibit Hall

Presenter: C. Gregory Elliott, MD

Poster #: 584

Abstract #: 6036

Session: Pulmonary Vascular Disease: Pulmonary HTN Evaluation and

Treatment, ID #893

Poster Presentation: Goal-Directed Combination Therapy in Pulmonary

Arterial Hypertension (PAH): Study Design of COMPASS-3

Location: Convention Center, Exhibit Hall

Presenter: Fernando Torres, MD

Poster #: 573

Abstract #: 5963

About Tracleer(R) in Pulmonary Arterial Hypertension (PAH)

Tracleer(R) (bosentan), the first oral dual endothelin receptor antagonist, is approved for the treatment of pulmonary arterial hypertension (PAH) and made available by Actelion subsidiaries in the United States, the European Union, Japan, Australia, Canada, Switzerland and other markets worldwide.

Requires attention to two significant safety concerns: Potential for serious liver injury (including rare cases of liver failure and unexplained hepatic cirrhosis in a setting of close monitoring) -- Liver monitoring of all patients is essential prior to initiation of treatment and monthly thereafter. High potential for major birth defects -- Pregnancy must be excluded and prevented by two forms of birth control; monthly pregnancy tests should be obtained. Because of these risks, Tracleer is only supplied through a controlled distribution.

About Actelion Pharmaceuticals

Actelion Pharmaceuticals has pioneered research and development in the pulmonary arterial hypertension (PAH) disease area. More than 40,000 PAH patients have been prescribed Actelion's product Tracleer(R) (bosentan), an orally available dual endothelin receptor antagonist for patients with World Health Organization (WHO) Class III or IV PAH. Tracleer was approved in 2001 as the first oral treatment for PAH, and is currently approved in the U.S., the European Union, and other markets worldwide. In January 2007, Actelion acquired CoTherix, Inc., whose product Ventavis(R) is approved and marketed in the United States for the treatment of patients with NYHA Class III or IV PAH.

SOURCE Actelion Ltd
Copyright©2007 PR Newswire.
All rights reserved

Related biology technology :

1. Speaker announces business members of IT Task Force
2. Doyle announces technology tax credits for Berbee
3. Doyle announces new energy, global warming policies
4. Doyle announces $80M renewable energy strategy
5. GE announces first installation of Discovery VCT
6. UWM announces winners of RGI awards
7. Third Wave announces two senior management appointments
8. Mirus announces new method for making antibodies
9. Merge announces sofware updates, upcoming acquisition
10. Small Tree announces ethernet solution for Apple Xserv G5
11. TEKLYNX International announces new RFID software
Post Your Comments:
(Date:6/27/2016)...  Sequenom, Inc. (NASDAQ: SQNM ), a ... the development of innovative products and services, announced today ... States denied its petition to review decisions ... U.S. Patent No. 6,258,540 (",540 Patent") are not patent ... Supreme Court,s Mayo Collaborative Services v. Prometheus Laboratories decision.  ...
(Date:6/27/2016)... ... June 27, 2016 , ... Rolf K. Hoffmann, ... faculty of the University of North Carolina Kenan-Flagler Business School effective ... at UNC Kenan-Flagler, with a focus on the school’s international efforts, leading classes ...
(Date:6/24/2016)... DIEGO , June 24, 2016 ... more sensitively detects cancers susceptible to PARP inhibitors ... circulating tumor cells (CTCs). The new test has ... HRD-targeted therapeutics in multiple cancer types. ... targeting DNA damage response pathways, including PARP, ATM, ...
(Date:6/23/2016)... ... June 23, 2016 , ... ... announce the launch of their brand, UP4™ Probiotics, into Target stores nationwide. The ... is proud to add Target to its list of well-respected retailers. This list ...
Breaking Biology Technology:
(Date:6/22/2016)...  The American College of Medical Genetics and Genomics was ... as one of the fastest-growing trade shows during the Fastest ... in Las Vegas . ... in each of the following categories: net square feet of ... attendees. The 2015 ACMG Annual Meeting was ranked 23 out ...
(Date:6/16/2016)... SAN FRANCISCO , June 16, 2016 /PRNewswire/ ... Market size is expected to reach USD ... report by Grand View Research, Inc. Technological proliferation ... and banking applications are expected to drive the ... ) , The development of ...
(Date:6/3/2016)... 3, 2016 Das ... Nepal hat ein 44 ... geprägter Kennzeichen, einschließlich Personalisierung, Registrierung und IT-Infrastruktur, ... Produktion und Implementierung von Identitätsmanagementlösungen. Zahlreiche renommierte ... Januar teilgenommen, aber Decatur wurde als konformste ...
Breaking Biology News(10 mins):