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Acologix Presents Preclinical Data on Cartilage Regeneration by AC-100 at the 30th ASBMR Annual Meeting
Date:9/12/2008

f AC-100 in osteoarthritis and traumatic cartilage injury," said Dr. Dawn McGuire, Chief Medical Officer of Acologix. "AC-100 is unique as a medical treatment potentially promoting regeneration of injured cartilage and underlying bone, as well as providing meaningful symptomatic relief."

Acologix, Inc.

Acologix, Inc. a privately held biopharmaceutical company, is developing and commercializing novel biopharmaceuticals targeting osteo-renal indications, including the complications with chronic kidney disease and dialysis, bone and cartilage repair and regeneration, and general dental and oral care. The company's most advanced program, AC-820 (TRK-820) is in Phase 3 and registration stages in the U.S. and Japan, respectively for the treatment of uremic pruritus in dialysis patients. The second program, AC-100, a new class of hard tissue growth promoting molecule, has been studied in two Phase II clinical studies and demonstrated high safety profile and selective hard tissue formation activities in dental restoration procedures. Further studies have revealed more evidences that AC-100 selectively promotes bone and cartilage repair and regeneration. Acologix is also developing AC-200 (Phosphatonin) to treat hyperphosphatemia and renal osteodystrophy. For more information, go to http://www.acologix.com.

Abstract Number 193 "AC-100 Promotes Cartilage Repair and Sub-Chondral Bone Healing in Surgically Induced Cartilage Defects." by Catherine Middleton-Hardie, Ph.D., David Rosen, Ph.D., Birthe Schnegelsberg, Ph.D., Robert Spiro, Ph.D. of Acologix, Harold Aberman, D.V.M., Tim Simon, Ph.D. of Applied Biological Concepts. Presented as Poster #SA111 by Dr. Middleton-Hardie on Saturday, September 13, 2008, at the 30th ASBMR Annual Meeting in Montreal, Canada.

This press release contains "forward-looking" statements. These statements involve risks and uncertainties, which may cause results to differ m
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