Navigation Links
Acacia Pharma Raises £15 Million ($23.5 Million) to Advance Clinical Development of Lead Products for Supportive Care

CAMBRIDGE, England, September 3, 2013 /PRNewswire/ --

Acacia Pharma, a pharmaceutical company specialising in the development of drugs for supportive care, announces it has raised £15 million (~$23.5 million) in a Series B financing led by Fidelity Biosciences and Novo A/S. Current investors Gilde Healthcare and Lundbeckfond Ventures also participated in the round. Dr Alex Pasteur of Fidelity Biosciences and Dr Martin Edwards of Novo A/S have joined the Board of Acacia Pharma as Non-executive Directors.

Acacia Pharma will use the proceeds to:

  • complete Phase III development of APD421 for the prevention of post-operative nausea & vomiting (PONV);
  • complete Phase II development of APD403 for the prevention of chemotherapy induced nausea & vomiting (CINV); and
  • develop the commercial presentation of APD515 for the treatment of xerostomia (dry mouth) in advanced cancer patients.

"I am delighted to welcome Fidelity and Novo to the Company and would like to thank Gilde and Lundbeckfond for their continued support," commented Dr Julian Gilbert, Acacia Pharma's CEO. "The Company is about to initiate a number of key studies with results being available in 2014. The data generated to date in PONV, CINV and xerostomia have been excellent; therefore we look forward to continued success."

Dr Alex Pasteur of Fidelity Biosciences added, "Significant numbers of post-surgical patients do not receive adequate nausea and vomiting prophylaxis. APD421, Acacia Pharma's lead product, a D2/D3 antagonist, showed excellent efficacy in its Phase II trial, and had a very good safety profile. We believe that a drug with this novel mechanism and displaying these characteristics can provide a major contribution to the care of post-surgical patients."

Dr Martin Edwards of Novo A/S stated, "In addition to APD421, Acacia Pharma has generated excellent Phase II a proof-of-concept data on APD403 in CINV. The drug, the same D2/D3 antagonist used in APD421, appears to have a unique anti-nauseant profile and can be added to current recommended CINV regimens due to its novel, complementary, mechanism of action, thereby targeting the key unmet need within this debilitating condition. We have high hopes for APD403 and for the future success of the Company."

About Acacia Pharma

Acacia Pharma ( is a pharmaceutical company focused on supportive care, a significant commercial opportunity. Growth in the cancer supportive care market has been driven by the increasing incidence of cancer, the expansion of effective cancer therapies and the desire to improve both the effectiveness of treatment and the quality of life of cancer patients.

Acacia Pharma has generated a pipeline of product opportunities addressing a range of supportive care indications such as nausea & vomiting, xerostomia and cachexia using a commercially driven approach to product discovery based on known drugs. This strategy leads to product opportunities with a higher probability of success and enables rapid clinical proof-of concept. In addition, Acacia Pharma's products are expected to reach the market quickly given that they are based on the novel use of well-characterised pharmaceuticals.

Acacia Pharma is led by an experienced management team who have already successfully built and exited life sciences companies. Management, Gilde Healthcare Lundbeckfond Ventures, Fidelity Biosciences and Novo Ventures are the Company's key shareholders. Acacia Pharma is based in Cambridge, UK.

About Fidelity Biosciences

Fidelity Biosciences ( invests venture capital in biopharmaceutical, medical technology, healthcare information technology and healthcare service companies. The firm is a subsidiary of FMR LLC, the parent company of Fidelity Investments, one of the world's leading providers of financial services. For more than 40 years, Fidelity has been a significant presence in the venture capital and private equity industry. For more information, visit the website above.

About Novo A/S

Novo ( the holding company of the Novo Group, and is wholly owned by the Novo Nordisk Foundation. It was established in 1999 to manage the assets of the foundation and actively make investments on its behalf. Novo Ventures focuses on life sciences venture capital, and is active in both Europe and North America. The firm has four partners in Copenhagen, one in London and four in San Francisco. With an evergreen structure, it annually invests approximately $150 million in venture capital into private and public life sciences companies.

About Lundbeckfond Ventures

Lundbeckfond Ventures ( is an evergreen life science venture fund investing in companies in Europe and in the US. It is financially driven and invests primarily in drug development, as well as in medtech. Lundbeckfond Ventures is part of the asset management subsidiary of the Lundbeck Foundation which in addition to substantial financial assets has controlling ownerships in H. Lundbeck A/S, ALK-Abelló A/S and Falk A/S.

About Gilde Healthcare 
Gilde Healthcare (Utrecht, The Netherlands and Cambridge, USA) is a transatlantic growth capital investor focused on private healthcare companies. It has over €450 million ($600 million) under management and is actively looking to lead new investments in therapeutics, diagnostics, medical devices and healthcare services.

For a list of Gilde's portfolio companies please visit the website at

SOURCE Acacia Pharma
Copyright©2012 PR Newswire.
All rights reserved

Related biology technology :

1. 6th BSMA Annual Executive Summit to Address the Supply Chain Challenges and Solutions of Biopharma
2. Before the Bell Scans: Hologic Inc., St. Jude Medical Inc., ResMed Inc., and Navidea Biopharmaceuticals Inc.
3. BIOPHARMA Executives Summit, 6th BSMA Annual Conference: Look Who Is Confirmed to Speak
4. EnduRx Pharmaceuticals to Present at 2013 Rocky Mountain Life Science Investor and Partnering Conference
5. Rational Design of Modified Release Dosage Forms: From Pharmacokinetic Targets Through Technology Selection, new life science webinar hosted by Xtalks
6. New Book Provides Industry Guidance for Major Pharmaceutical Firms
7. HealthCare, Technology Briefing: Market Movers for the Week - Technologies-Scan Corp, GNC, Galena Biopharma, Immunomedics, Amarin
8. Pharma Contract Manufacturing, Research & Packaging Market a New Report Available at
9. Cambridge Semantics to Present on Smart Data and Competitive Intelligence Informatics at 2013 Pharma CI Conference & Exposition
10. Pharmaceutical and Food Product Safety Made Easier with the Environmental Wireless Validation System by Deadline Solutions, Inc
11. FDAs Lawrence Yu to Participate in Live Video Chat on Question-Based Review (QbR) for Generics on CPhI Pharma Evolution
Post Your Comments:
(Date:11/24/2015)... FAR HILLS, N.J. (PRWEB) , ... November 24, 2015 , ... ... University, as the recipient of the 2016 USGA Green Section Award. Presented annually since ... of golf through his or her work with turfgrass. , Clarke, of ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... ... maintain healthy metabolism. But unless it is bound to proteins, copper is also ... Health (NIH), researchers at Worcester Polytechnic Institute (WPI) will conduct a systematic study ...
(Date:11/24/2015)... India , November 24, 2015 ... a new market research report "Oligonucleotide Synthesis Market by ... Application (PCR, Gene Synthesis, Diagnostic, DNA, RNAi), End-User (Research, ... 2020", published by MarketsandMarkets, the market is expected to ... Million in 2015, at a CAGR of 10.1% during ...
(Date:11/24/2015)... 2015 --> ... released by Transparency Market Research, the global non-invasive prenatal ... of 17.5% during the period between 2014 and 2022. ... Industry Analysis, Size, Volume, Share, Growth, Trends and Forecast ... market to reach a valuation of US$2.38 bn by ...
Breaking Biology Technology:
(Date:11/17/2015)... Paris from 17 th until 19 ... from 17 th until 19 th November 2015. ... invented the first combined scanner in the world which scans ... now two different scanners were required: one for passports and ... the same surface. This innovation is an ideal solution for ...
(Date:11/17/2015)... 2015 Pressure BioSciences, Inc. (OTCQB: PBIO) ("PBI" ... sale of broadly enabling, pressure cycling technology ("PCT")-based sample ... announced it has received gross proceeds of $745,000 from ... (the "Offering"), increasing the total amount raised to date ... closings are expected in the near future. ...
(Date:11/12/2015)... Mass. , Nov. 12, 2015  Arxspan ... Institute of MIT and Harvard for use of ... discovery information management tools. The partnership will support ... both biological and chemical research information internally and ... will be used for managing the Institute,s electronic ...
Breaking Biology News(10 mins):