Navigation Links
Absorption Systems Announces License Agreement with Pfizer Inc.
Date:7/15/2014

EXTON, Pa., July 15, 2014 /PRNewswire/ -- Absorption Systems, a leader in novel test systems for drug transporters, announces a license agreement with Pfizer Inc., in which Pfizer will in-license Absorption Systems' BCRP-MDCK cells. This cell line is stably transfected with the human ABCG2 gene, which codes for a protein known as BCRP (breast cancer resistance protein).

This proprietary human BCRP assay system is designed to enable the testing of new drug candidates for interactions with the BCRP protein, which is involved in drug clearance, blood-brain barrier penetration, resistance of tumors to anticancer drugs, and drug-drug interactions. As a result of BCRP interactions, compounds that show promising efficacy in vitro may be inaccessible to the organ of interest during clinical trials.

"We believe that, because of their robust expression of the BCRP protein, BCRP-MDCK cells can allow users to better predict human outcomes during preclinical testing of their drug candidates, thereby having the potential to reduce attrition during drug development," said Ismael J. Hidalgo, Ph.D., CSO, Absorption Systems.

About Absorption Systems

Absorption Systems assists pharmaceutical, biotechnology and medical device companies in identifying and overcoming absorption, distribution, metabolism, excretion, and toxicity (ADMET) barriers in the development of drugs, biologics, and medical devices. The company's mission is to continually develop innovative research tools and provide exemplary service that can be used to accurately predict human outcomes or to explain unanticipated human outcomes when they occur.  The CellPort Technologies® platform, a suite of human cell-based test systems for drug transporter characterization, exemplifies Absorption Systems' commitment to innovation while continually striving to be the industry assay standard for in vitro drug interaction assessment. Absorption Systems has facilities near Philadelphia, PA, and in San Diego, CA and Panama City, Panama, and serves customers throughout the world. For information on the company's comprehensive contract services and applied research programs, please visit absorption.com.

Chris Bode
610-280-1451
cbode@absorption.com 


'/>"/>
SOURCE Absorption Systems
Copyright©2014 PR Newswire.
All rights reserved

Related biology technology :

1. Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems
2. Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information
3. Winter Construction is Simple with Starrco’s Modular Office Systems
4. WaferGen Bio-systems Acquires a Leading Next-Generation Sequencing (NGS) Library Preparation Business and Announces Changes to its Board of Directors
5. United Technologies plans $10 million investment for UConn systems engineering institute
6. Systems Upgrade Keeps Neurotechnology Company on the Leading Edge
7. Annai Systems to Support International Challenge to Improve the Detection of Cancer Mutations
8. WaferGen Bio-systems Reports Q3 13 Results and Commercial Focus on Target Enrichment for Next-Gen Sequencing (NGS)
9. FAA’s Integration of Civil Unmanned Aircraft Systems in the National Airspace System Roadmap
10. Channel Medsystems Receives Health Canada Approval to Begin Clinical Evaluation of its Innovative Procedure for Heavy Menstrual Bleeding; Hires Mary Edwards as Senior Vice President, Clinical and Regulatory Affairs.
11. Journal of Astronomical Telescopes, Instruments, and Systems (JATIS) Will Launch in Mid-2014
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/11/2017)... Oct. 11, 2017  VMS BioMarketing, a leading provider of ... oncology Clinical Nurse Educator (CNE) network, which will launch this ... communication among health care professionals to enhance the patient care ... staff, and other health care professionals to help women who ... ...
(Date:10/11/2017)... ... October 11, 2017 , ... Disappearing forests and increased ... of over 5.5 million people each year. Especially those living in larger cities are ... - based in one of the most pollution-affected countries globally - decided to take ...
(Date:10/11/2017)... ... October 11, 2017 , ... ... granted orphan drug designation to SBT-100, its novel anti-STAT3 (Signal Transducer and Activator ... osteosarcoma. SBT-100 is able to cross the cell membrane and bind intracellular STAT3 ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... targeted antibody-drug conjugate (ADC) therapeutics, today confirmed licensing rights that give it ... Nanoparticle), a technology developed in collaboration with Children’s Hospital Los Angeles (CHLA). ...
Breaking Biology Technology:
(Date:4/11/2017)... PALM BEACH GARDENS, Fla. , April 11, ... biometric identity management and secure authentication solutions, today ... million contract by Intelligence Advanced Research Projects Activity ... technologies for IARPA,s Thor program. "Innovation ... the onset and IARPA,s Thor program will allow ...
(Date:4/11/2017)... , April 11, 2017 NXT-ID, ... security technology company, announces the appointment of independent Directors Mr. ... to its Board of Directors, furthering the company,s corporate ... ... NXT-ID, we look forward to their guidance and benefiting from ...
(Date:4/5/2017)... 5, 2017 Today HYPR Corp. , ... server component of the HYPR platform is officially ... end-to-end security architecture that empowers biometric authentication across Fortune ... already secured over 15 million users across the financial ... connected home product suites and physical access represent a ...
Breaking Biology News(10 mins):