Navigation Links
Absorption Systems Announces License Agreement with Pfizer Inc.

EXTON, Pa., July 15, 2014 /PRNewswire/ -- Absorption Systems, a leader in novel test systems for drug transporters, announces a license agreement with Pfizer Inc., in which Pfizer will in-license Absorption Systems' BCRP-MDCK cells. This cell line is stably transfected with the human ABCG2 gene, which codes for a protein known as BCRP (breast cancer resistance protein).

This proprietary human BCRP assay system is designed to enable the testing of new drug candidates for interactions with the BCRP protein, which is involved in drug clearance, blood-brain barrier penetration, resistance of tumors to anticancer drugs, and drug-drug interactions. As a result of BCRP interactions, compounds that show promising efficacy in vitro may be inaccessible to the organ of interest during clinical trials.

"We believe that, because of their robust expression of the BCRP protein, BCRP-MDCK cells can allow users to better predict human outcomes during preclinical testing of their drug candidates, thereby having the potential to reduce attrition during drug development," said Ismael J. Hidalgo, Ph.D., CSO, Absorption Systems.

About Absorption Systems

Absorption Systems assists pharmaceutical, biotechnology and medical device companies in identifying and overcoming absorption, distribution, metabolism, excretion, and toxicity (ADMET) barriers in the development of drugs, biologics, and medical devices. The company's mission is to continually develop innovative research tools and provide exemplary service that can be used to accurately predict human outcomes or to explain unanticipated human outcomes when they occur.  The CellPort Technologies® platform, a suite of human cell-based test systems for drug transporter characterization, exemplifies Absorption Systems' commitment to innovation while continually striving to be the industry assay standard for in vitro drug interaction assessment. Absorption Systems has facilities near Philadelphia, PA, and in San Diego, CA and Panama City, Panama, and serves customers throughout the world. For information on the company's comprehensive contract services and applied research programs, please visit

Chris Bode

SOURCE Absorption Systems
Copyright©2014 PR Newswire.
All rights reserved

Related biology technology :

1. Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems
2. Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information
3. Winter Construction is Simple with Starrco’s Modular Office Systems
4. WaferGen Bio-systems Acquires a Leading Next-Generation Sequencing (NGS) Library Preparation Business and Announces Changes to its Board of Directors
5. United Technologies plans $10 million investment for UConn systems engineering institute
6. Systems Upgrade Keeps Neurotechnology Company on the Leading Edge
7. Annai Systems to Support International Challenge to Improve the Detection of Cancer Mutations
8. WaferGen Bio-systems Reports Q3 13 Results and Commercial Focus on Target Enrichment for Next-Gen Sequencing (NGS)
9. FAA’s Integration of Civil Unmanned Aircraft Systems in the National Airspace System Roadmap
10. Channel Medsystems Receives Health Canada Approval to Begin Clinical Evaluation of its Innovative Procedure for Heavy Menstrual Bleeding; Hires Mary Edwards as Senior Vice President, Clinical and Regulatory Affairs.
11. Journal of Astronomical Telescopes, Instruments, and Systems (JATIS) Will Launch in Mid-2014
Post Your Comments:
(Date:11/25/2015)... HOLLISTON, Mass. , Nov. 25, 2015 ... a biotechnology company developing bioengineered organ implants for life-threatening ... will present at the LD Micro "Main Event" investor ... PT. The presentation will be webcast live and posted ... also be available at the conference for one-on-one meetings ...
(Date:11/25/2015)... , Nov. 25, 2015 Orexigen® Therapeutics, Inc. ... participate in a fireside chat discussion at the Piper ... York . The discussion is scheduled for Wednesday, ... .  A replay will be available for ... Stilwell  , Julie NormartVP, Corporate Communications and Business ...
(Date:11/24/2015)... ... ... The United States Golf Association (USGA) today announced Dr. Bruce Clarke, of ... since 1961, the USGA Green Section Award recognizes an individual’s distinguished service to the ... of Iselin, N.J., is an extension specialist of turfgrass pathology in the department of ...
(Date:11/24/2015)... ... November 24, 2015 , ... Copper is an essential ... bound to proteins, copper is also toxic to cells. With a $1.3 million ... (WPI) will conduct a systematic study of copper in the bacteria Pseudomonas aeruginosa ...
Breaking Biology Technology:
(Date:11/12/2015)... Mass. , Nov. 12, 2015  Arxspan ... Institute of MIT and Harvard for use of ... discovery information management tools. The partnership will support ... both biological and chemical research information internally and ... will be used for managing the Institute,s electronic ...
(Date:11/10/2015)... Nov. 10, 2015 About ... that helps to identify and verify the identity ... considered as the secure and accurate method of ... a particular individual because each individual,s signature is ... especially when dynamic signature of an individual is ...
(Date:11/2/2015)... Nov. 2, 2015  SRI International has been awarded ... preclinical development services to the National Cancer Institute (NCI) ... provide scientific expertise, modern testing and support facilities, and ... pharmacology and toxicology studies to evaluate potential cancer prevention ... The PREVENT Cancer Drug Development Program is an NCI-supported ...
Breaking Biology News(10 mins):