Navigation Links
Absorption Systems Announces License Agreement with Pfizer Inc.
Date:7/15/2014

EXTON, Pa., July 15, 2014 /PRNewswire/ -- Absorption Systems, a leader in novel test systems for drug transporters, announces a license agreement with Pfizer Inc., in which Pfizer will in-license Absorption Systems' BCRP-MDCK cells. This cell line is stably transfected with the human ABCG2 gene, which codes for a protein known as BCRP (breast cancer resistance protein).

This proprietary human BCRP assay system is designed to enable the testing of new drug candidates for interactions with the BCRP protein, which is involved in drug clearance, blood-brain barrier penetration, resistance of tumors to anticancer drugs, and drug-drug interactions. As a result of BCRP interactions, compounds that show promising efficacy in vitro may be inaccessible to the organ of interest during clinical trials.

"We believe that, because of their robust expression of the BCRP protein, BCRP-MDCK cells can allow users to better predict human outcomes during preclinical testing of their drug candidates, thereby having the potential to reduce attrition during drug development," said Ismael J. Hidalgo, Ph.D., CSO, Absorption Systems.

About Absorption Systems

Absorption Systems assists pharmaceutical, biotechnology and medical device companies in identifying and overcoming absorption, distribution, metabolism, excretion, and toxicity (ADMET) barriers in the development of drugs, biologics, and medical devices. The company's mission is to continually develop innovative research tools and provide exemplary service that can be used to accurately predict human outcomes or to explain unanticipated human outcomes when they occur.  The CellPort Technologies® platform, a suite of human cell-based test systems for drug transporter characterization, exemplifies Absorption Systems' commitment to innovation while continually striving to be the industry assay standard for in vitro drug interaction assessment. Absorption Systems has facilities near Philadelphia, PA, and in San Diego, CA and Panama City, Panama, and serves customers throughout the world. For information on the company's comprehensive contract services and applied research programs, please visit absorption.com.

Chris Bode
610-280-1451
cbode@absorption.com 


'/>"/>
SOURCE Absorption Systems
Copyright©2014 PR Newswire.
All rights reserved

Related biology technology :

1. Niagara Thermal Products LLC Selected as Critical Supplier for Buffalo BioBlower Air Purification Systems
2. Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information
3. Winter Construction is Simple with Starrco’s Modular Office Systems
4. WaferGen Bio-systems Acquires a Leading Next-Generation Sequencing (NGS) Library Preparation Business and Announces Changes to its Board of Directors
5. United Technologies plans $10 million investment for UConn systems engineering institute
6. Systems Upgrade Keeps Neurotechnology Company on the Leading Edge
7. Annai Systems to Support International Challenge to Improve the Detection of Cancer Mutations
8. WaferGen Bio-systems Reports Q3 13 Results and Commercial Focus on Target Enrichment for Next-Gen Sequencing (NGS)
9. FAA’s Integration of Civil Unmanned Aircraft Systems in the National Airspace System Roadmap
10. Channel Medsystems Receives Health Canada Approval to Begin Clinical Evaluation of its Innovative Procedure for Heavy Menstrual Bleeding; Hires Mary Edwards as Senior Vice President, Clinical and Regulatory Affairs.
11. Journal of Astronomical Telescopes, Instruments, and Systems (JATIS) Will Launch in Mid-2014
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2016)... ... 23, 2016 , ... UAS LifeSciences, one of the leading ... UP4™ Probiotics, into Target stores nationwide. The company, which has been manufacturing high ... its list of well-respected retailers. This list includes such fine stores as Whole ...
(Date:6/23/2016)... June 23, 2016 /PRNewswire/ - FACIT has announced ... biotechnology company, Propellon Therapeutics Inc. ("Propellon" ... commercialization of a portfolio of first-in-class WDR5 inhibitors ... such as WDR5 represent an exciting class of ... precision medicine for cancer patients. Substantial advances have ...
(Date:6/23/2016)... 23, 2016 Houston Methodist Willowbrook Hospital ... Sports Association to serve as their official health ... Methodist Willowbrook will provide sponsorship support, athletic training ... association coaches, volunteers, athletes and families. ... Sports Association and to bring Houston Methodist quality ...
(Date:6/23/2016)... June 23, 2016  The Prostate Cancer Foundation (PCF) is pleased ... and faster cures for prostate cancer. Members of the Class of 2016 were ... Read More About the Class of 2016 PCF Young ... ... ...
Breaking Biology Technology:
(Date:4/28/2016)... 28, 2016 First quarter 2016:   ... compared with the first quarter of 2015 The gross ... M (loss: 18.8) and the operating margin was 40% (-13) ... Cash flow from operations was SEK 249.9 M (21.2) , ... is unchanged, SEK 7,000-8,500 M. The operating margin for ...
(Date:4/15/2016)... 2016 Research and Markets has ... Market 2016-2020,"  report to their offering.  , ... ,The global gait biometrics market is expected to ... period 2016-2020. Gait analysis generates multiple ... used to compute factors that are not or ...
(Date:3/29/2016)... 29, 2016 LegacyXChange, Inc. (OTC: ... and SelectaDNA/CSI Protect are pleased to announce our successful ... a variety of writing instruments, ensuring athletes signatures against ... collectibles from athletes on LegacyXChange will be assured of ... DNA. Bill Bollander , CEO states, ...
Breaking Biology News(10 mins):