Navigation Links
ARIUS presents new findings showing therapeutic antibody inhibits human leukemic cancer stem cells
Date:2/13/2008

- Data on ARIUS' novel CD9 therapeutic antibody to be presented at AACR

Special Conference on Cancer Stem Cells -

TORONTO, Feb. 13 /PRNewswire-FirstCall/ - ARIUS Research Inc., (TSX: ARI), a biotechnology company discovering and developing the next wave of antibody therapeutics, today announced that new information on the preclinical activity of its anti-CD9 cancer stem cell antibody will be presented at the AACR Special Conference on Cancer Stem Cells entitled "The Role of Cancer Stem Cells in the Initiation and Propagation of Tumorigenesis," held on February 12th-15th in Los Angeles. The Company will disclose data demonstrating that its CD9 antibody not only targets leukemia cancer stem cells, but also leads to a dramatic reduction in their capacity to self-renew or give rise to further leukemia. These findings were discovered in collaboration with John E. Dick, PhD, the Canada Research Chair in Stem Cell Biology with the University Health Network in Toronto, Canada.

The poster presentation (Wednesday, February 13th 2008, from 4:30-6:30 pm) will outline the activity of ARIUS' anti-CD9 antibody, AR40A746.2.3, against acute myeloid leukemia (AML). The long-term survival expectation for patients with AML is poor due to disease relapse and resistance to chemotherapy. CD9 appears to be an important driver for leukemia and potentially other cancer stem cells, which often survive treatment, continue to multiply and go on to seed new tumors. Studies of patients with different types of cancer have demonstrated that the presence of CD9 can be linked to lower survival rates. AR40A746.2.3 has previously been found to control tumor growth and improve survival in pre-clinical breast and pancreatic cancer models.

"Since some cancer stem cells have been shown to be highly resistant to traditional cancer therapies and are believed to contribute to treatment resistance, the selectivity of ARIUS' anti-CD9 antibody for leukemic cancer stem
'/>"/>

SOURCE ARIUS Research Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related biology technology :

1. Arius Features Preclinical Data on Antibody Candidates at Two Conferences
2. ARIUS Announces Third Quarter Fiscal 2007 Financial Results
3. Arius highlighted at AACR-NCI-EORTC 2007 International Cancer Conference
4. ARIUS to present at Chinese Global Financial Forum
5. ARIUS announces cancer stem cell antibody program successfully completes first toxicology study
6. Arius announces new findings in Trop-2 and CD59 CANCER antibody programs
7. ARIUS to present at BioNorth Biotechnology and Life Sciences Conference
8. ARIUS announces manufacturing agreement with Avid Bioservices for CD44 Cancer Stem Cell antibody
9. ARIUS to Hold Fourth Quarter and Year End 2007 Conference Call
10. Arius completes Pre-IND Meeting with FDA for Lead CD44 Cancer Stem Cell Program
11. ARIUS announces fourth quarter and year-end fiscal 2007 financial results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/27/2015)... , Feb. 27, 2015 Bionomics Limited ... the DisrupTOR-1 trial of BNC105 in patients with metastatic ... Orlando, Florida . The data will ... the City of Hope Comprehensive Cancer Center in ... The new data identifies Ferritin and IL-8 ...
(Date:2/27/2015)...  Steep Hill, the industry leader in cannabis testing ... open a full service medical cannabis quality assurance laboratory ... advanced scientific tools and methodology to the state, for ... currently the only laboratory licensed by the New Mexico ... in order to meet the recently adopted regulatory requirements ...
(Date:2/26/2015)... Feb. 26, 2015  23andMe, the leading personal genetics ... as Privacy Officer and Corporate Counsel. Black brings ... laws as well as health care regulations. As a ... be responsible for reviewing, updating and enhancing the company,s ... and abroad. She joined the company January 5, 2015 ...
(Date:2/26/2015)... , Feb. 26, 2015 Protiviti ( www.protiviti.com ... version of the Governance Portal , designed to ... and compliance (GRC) tasks across multiple business units and ... to help customers better align their controls with the ... Commission ) requirements. In response to client feedback, Protiviti ...
Breaking Biology Technology:New BNC105 Biomarker Data to be Presented at US Cancer Conference 2New BNC105 Biomarker Data to be Presented at US Cancer Conference 3New BNC105 Biomarker Data to be Presented at US Cancer Conference 4New BNC105 Biomarker Data to be Presented at US Cancer Conference 5Steep Hill First to Receive Provisional Approval to Establish Laboratory Services for Cannabis Testing in State of New Mexico 223andMe Appoints Kate Black as Privacy Officer and Corporate Counsel 2Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 2Protiviti Governance Portal Helps Companies Drive Governance, Risk and Compliance Productivity Across Multiple Business Units 3
... , Introduction ... used to display data from all SPEX instruments. DataMax can ... map displays multifiles or 3-D data, and looks much like a geographical ... X values are plotted on the horizontal axis, and z values are ...
... , ... The SPEX FLUOROLOG ... other accessories. The standard FLUOROLOG configuration has an R928P ... 850 nm. For near-IR fluores-cence measurements, an optional solid-state de-tector (DSS-IGA020L) ...
... , , ... Protein-containing plants are staples in the diets of all countries. The ability ... people have to have enough to eat before they can advance to higher ... the amount of rainfall, the occurrence of frost, wind erosion, etc., can be ...
Cached Biology Technology:Obtaining a contour map from multifiles or 3D data in DataMax 2Obtaining a contour map from multifiles or 3D data in DataMax 3Food science: increasing crop yields 2
(Date:2/5/2015)... IRVINE, Calif. , Jan. 27, 2015 ... trusted provider of globally deployed, innovative test ... today announced the delivery of its ... Martin Space Systems Company (LMSSC). GENASYS is ... the demands of mission-critical applications that require ...
(Date:2/5/2015)... 2015 NXT-ID, Inc. (NASDAQ: NXTD ... authentication company focused on the growing mobile commerce market, ... Online CEO Conference on January 29 th at ... , CEO of NXT-ID will present and host a ... smart wallet and its full suite of biometric technologies. ...
(Date:2/5/2015)... , Jan. 30, 2015  It is gratifying to ... and potential for genomic science as a means to ... prevention and treatment.  I was honored to participate in ... precision medicine program. Since the 1980s ... of genomics—from the first sequenced genome of a free ...
Breaking Biology News(10 mins):Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 2Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 3Marvin Test Solutions' GENASYS Platform Advances Mission-Critical Aerospace Production Test 4CEO of NXT-ID, Inc. to Discuss Company's Biometric Technologies at RedChip Online Conference January 29th 2CEO of NXT-ID, Inc. to Discuss Company's Biometric Technologies at RedChip Online Conference January 29th 3J. Craig Venter, Ph.D., Co-Founder and CEO, Human Longevity, Inc. (HLI) Participates in White House Precision Medicine Event 2
... many as 18 percent of adults who have no history ... stroke, according to results of a large national study published ... one of the JAMA/Archives journals. , Using brain imaging to ... have had an undiagnosed or silent stroke, according to background ...
... intensive care unit (ICU) previously occupied by a ... of acquiring such bacteria, according to a report ... Internal Medicine, one of the JAMA/Archives journals. , ... in hospitals: methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant ...
... approach, researchers at Children's Hospital Boston have demonstrated that ... a heart attack and protect the heart from scarring. ... a natural inhibitor of cell division with a naturally ... Together, these two agents enabled heart-muscle cells to multiply ...
Cached Biology News:Stroke symptoms common among general population 2Transmission of antibiotic-resistant bacteria linked to previous intensive care unit room occupants 2Rescuing injured hearts by enhancing regeneration 2Rescuing injured hearts by enhancing regeneration 3
Donor feline serum and plasma...
NPT1 (M-19)...
8 different frozen tissues are mounted on positively charged glass slides...
... Combining linear motor and ... offer pre-engineered Cartesian solutions that ... cable management, and motors., , ... , Pass through high-flex cabling ...
Biology Products: