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ALPCO Introduces a Mouse HMW and Total Adiponectin ELISA
Date:8/7/2009

SALEM, N.H., Aug. 7 /PRNewswire/ -- ALPCO Diagnostics has introduced a Mouse HMW Adiponectin ELISA kit that facilitates the testing process for this biomarker. This ELISA is unique; it is a departure from other methods for determining mouse HMW adiponectin and was first introduced in a pre-market form in a correspondence from Dr. Hiroyuki Ebinuma of the Tsukuba Research Institute in the journal Clinica Chimica Acta in February 2009.

Recently, an ELISA system was developed for the selective quantification of human adiponectin oligomers using protease pretreatment, and the Mouse HMW Adiponectin ELISA kit reflects a similar system for simultaneous detection of both high-molecular-weight (HMW) and total adiponectin. The human multimeric adiponectin ELISA from ALPCO and Sekisui has been cited in many publications, and is trusted by the research community worldwide for its consistency and quality. The new mouse HMW and total adiponectin ELISA has been held to the same exacting standards of quality in research, development and pre-market testing.

The Mouse HMW Adiponectin ELISA from ALPCO is differentiated from other ELISA methods on the market by simultaneously measuring both HMW and total adiponectin levels. Other available methods for measuring HMW adiponectin in mouse samples do not have a corresponding method for assessing total adiponectin available from the same manufacturer. Given the lack of an international reference standard for adiponectin, the determination of both HMW and total adiponectin using the same ELISA is preferable to eliminate this source of bias in the ratio.

The interest in animal models of insulin sensitivity in obese and pre-diabetic conditions continues to grow. Dr. Kelly Scribner Doering, Market Research Analyst with ALPCO, states, "Adipone
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SOURCE ALPCO Diagnostics
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