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ALPCO Introduces a Mouse HMW and Total Adiponectin ELISA
Date:8/7/2009

SALEM, N.H., Aug. 7 /PRNewswire/ -- ALPCO Diagnostics has introduced a Mouse HMW Adiponectin ELISA kit that facilitates the testing process for this biomarker. This ELISA is unique; it is a departure from other methods for determining mouse HMW adiponectin and was first introduced in a pre-market form in a correspondence from Dr. Hiroyuki Ebinuma of the Tsukuba Research Institute in the journal Clinica Chimica Acta in February 2009.

Recently, an ELISA system was developed for the selective quantification of human adiponectin oligomers using protease pretreatment, and the Mouse HMW Adiponectin ELISA kit reflects a similar system for simultaneous detection of both high-molecular-weight (HMW) and total adiponectin. The human multimeric adiponectin ELISA from ALPCO and Sekisui has been cited in many publications, and is trusted by the research community worldwide for its consistency and quality. The new mouse HMW and total adiponectin ELISA has been held to the same exacting standards of quality in research, development and pre-market testing.

The Mouse HMW Adiponectin ELISA from ALPCO is differentiated from other ELISA methods on the market by simultaneously measuring both HMW and total adiponectin levels. Other available methods for measuring HMW adiponectin in mouse samples do not have a corresponding method for assessing total adiponectin available from the same manufacturer. Given the lack of an international reference standard for adiponectin, the determination of both HMW and total adiponectin using the same ELISA is preferable to eliminate this source of bias in the ratio.

The interest in animal models of insulin sensitivity in obese and pre-diabetic conditions continues to grow. Dr. Kelly Scribner Doering, Market Research Analyst with ALPCO, states, "Adiponectin is positively associated with insulin sensitivity and this kit is specifically designed for mouse samples so it aids preclinical research. This mouse HMW adiponectin ELISA would be of interest to both academic institutions and biotech companies."

Julie Rasku, a scientist with ALPCO Diagnostics' development team assures us, "I found the mouse adiponectin assay to be highly reproducible with low variance. It is a reliable method to determine mouse adiponectin levels." The Mouse HMW and Total Adiponectin ELISA kit provides a tremendous number of benefits and is truly one of a kind. ALPCO and Sekisui Medical Corporation are pleased to introduce this promising new research tool.

ALPCO was founded in 1990 as an importer and distributor of high quality research immunoassay kits. Since that time, their primary goals have been to offer a diverse line of assays that appeal to their broad customer base while also providing exceptional customer service and product support. In recent years, ALPCO has solidified its place in the market not only as a distributor but as a developer and manufacturer of immunoassays as well.

    CONTACT:
    Kate Kaplan
    800-592-5726


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SOURCE ALPCO Diagnostics
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