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AFFiRiS AG: Vaccination Against Hypertension is Development Project No. 4 and has Already Been Awarded an FFG Grant of up to EUR 1.2 Million
Date:2/25/2010

imer's vaccination approach valued at up to EUR 430 million, shows that the pharmaceutical industry does already believe in our technology."

So far AFFiRiS AG had announced the development of two vaccines for Alzheimer's disease as well as one each for Parkinson's disease and atherosclerosis. These diseases affect hundreds of millions of people worldwide. The development of a vaccine for the treatment of hypertension is now of similar importance as hypertension is one of the major causes of diseases of the cardiovascular system and thus one of the most frequent causes of disease-induced deaths worldwide.

AFFiRiS AG is once again able to take advantage of its unique AFFITOME(R) platform technology which allows the generation of vaccines targeting autologous structures such as proteins and peptides. With Angiotensin II AFFiRiS AG is addressing a human hormone for the first time. This peptide hormone brings about vasoconstriction thereby increasing the blood pressure and is therefore presenting a promising target structure for intervention in chronic hypertension.

With regard to this therapy approach CSO Dr. Frank Mattner states: "Although chronic hypertension can be treated with drugs, the patient has to be precisely attuned to them and must then take medication constan
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SOURCE AFFiRiS AG
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