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AFCell Medical Reports Results from the Retrospective Study of a Novel Allograft Membrane to Prevent Post-Operative Adhesions in the Repair of Peroneal and Posterior Tibial Tendons
Date:9/4/2012

, Assistant Professor of Surgery, Harvard Medical School. All patients in the study had been treated with AmnioClear during surgery to repair peroneal or posterior tibial tendons.

Post-operatively, each patient in the study was asked to return to the clinic for further evaluation to determine whether or not there were any adhesions between the tendon repair site, and the surrounding tissues, including the overlying skin.

The assessment included a subjective assessment of the motility of the overlying skin at the incision site, and manual measurements of range of motion, to determine if any restrictions related to the surgical site could be identified. Each subject also was asked to complete a questionnaire to rate their pain and function on the day of examination and was asked to compare this to their symptoms prior to surgery. Pain and function were assessed with the Bristol Foot Score (BFS) and the Foot Function Index (FFI), both validated scoring systems that have been used to assess both pain and functional capacity.

In addition, under the direction of a physician with experience in ultrasound imaging, each repair site was assessed dynamically to determine the relative thickness of the repair site, as compared to the adjacent tendon, and was also compared to the contralateral limb.

The time after surgery ranged from 4 months to 3.5 years, with an average follow-up time of 1.72 years after surgery.

Results

Twelve (86%) of the patients in the study did not develop adhesions in or around the surgical site and only one patient developed an adhesion at the tendon repair site. Two patients developed adhesions in the skin (14%) and one of those patients also developed an adhesion at the tendon repair site (7%). Of the two cases where adhesions were observed in the skin, both were rated as mild to moderate, and the case in which a tendon adhesion appears to have occurred was more complex, and was rated as moderate. None of the a
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SOURCE AFCell Medical
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