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AEterna Zentaris To Present Data on Anticancer Compounds AEZS-112 and AEZS-126 at AACR Annual Meeting
Date:4/15/2009

QUEBEC CITY, April 15 /PRNewswire-FirstCall/ - AEterna Zentaris Inc. (TSX: AEZ; Nasdaq: AEZS), a global biopharmaceutical company focused on endocrine therapy and oncology, today announced that it will present two posters on its PI3K inhibitor compound, AEZS-126, as well as a poster on its orally-active tubulin and topoisomerase II inhibitor compound, AEZS-112, at the American Association for Cancer Research (AACR) Annual Meeting, to be held on April 18-22, 2009 at the Colorado Convention Center in Denver, Colorado.

    AEZS-126 (Poster #3705)

    - Entitled, "AEZS-126, a new orally bioavailable PI3K inhibitor with
      antitumor effects", I. Seipelt, S. Baasner, M. Gerlach, M. Teifel, J.
      Fensterle, L. Blumenstein, G. Mueller and E. Guenther, the poster
      focuses on ADMET and safety profiling of the compound, as well as in
      vivo pharmacokinetic experiments and mouse xenograft antitumor studies.

    AEZS-126 (Poster #3706)

    - Entitled, "In vitro profiling of the potent and selective PI3K
      inhibitor, AEZS-126", I. Seipelt, M. Gerlach, L. Blumenstein, G.
      Mueller, M.Teifel, E. Polymeropoulos and E. Guenther, the poster
      outlines the key in vitro characteristics of this compound that led to
      its selection for in vivo development.

    Both posters will be presented on Tuesday, April 21, 2009, between 8 a.m.
    and 12 p.m. (MT), during the Experimental and Molecular Therapeutics 23
    session in Hall B-F, Poster Section 35.

    AEZS-112 (Poster #5567)

    - Entitled, "Phase I dose-escalation, safety, and pharmacokinetic study
      of weekly oral AEZS-112, a small molecule anticancer agent in patients
      with advanced cancer and lymphoma", D. W. Northfelt, P. Griffin, H.
      Block, H. Sindermann, M. Teifel, D. Von Hoff, D. Mendelson, the poster
      outlines Phase 1 result
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SOURCE  AETERNA ZENTARIS INC.
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