AEterna Zentaris: New Data Published on its Ghrelin Antagonist Compound, AEZS-123 (JMV2959), Supports its Use in Alcohol... (ion said Ghrelin's action in the brain ...)

HOME >> BIOLOGY >> TECHNOLOGY

AEterna Zentaris: New Data Published on its Ghrelin Antagonist Compound, AEZS-123 (JMV2959), Supports its Use in Alcohol Addiction

Date:7/7/2009

ion said, "Ghrelin's action in the brain may be of importance for several addictions, including chemical drugs such as alcohol and even food."

Daniel Perrissoud, Senior Director of Project Management at AEterna Zentaris and one of the authors of the paper stated, "The discovery of the Gothenburg team that the reward system is a target of ghrelin effects, opens new development opportunities for our proprietary ghrelin receptor antagonists. In the field of addiction, the clinical proof of efficacy can be obtained in a more time- and cost-effective manner than in the field of obesity, as short-term clinical laboratory paradigms can be used for the clinical evaluation."

The article entitled, "Requirement of Central Ghrelin Signaling for Alcohol Reward" appears today in the July 7, 2009 issue of Proceedings of the National Academy of Sciences (PNAS 2009; 106:11318-11323) and was published on line on June 29, 2009 in the early edition of the journal.

About AEterna Zentaris' Ghrelin Antagonist Program

Ghrelin is a natural peptide hormone produced by the stomach that increases appetite and induces accumulation of fat tissue. The discovery of ghrelin and its receptors opens up new opportunities for the treatment of obesity and eating disorders through the use of ghrelin antagonists to suppress appetite and fat deposition.

In 2004, AEterna Zentaris signed two agreements for the development of ghrelin antagonists with the Institut des biomolecules Max Mousseron of the University of Montpellier, France, directed by Prof. Jean Martinez, and with the Department of Experimental and Environmental Medicine of the University of Milan, Italy, directed by Prof. Vittorio Locatelli. The research projects were targeting the chemical synthesis and pharmacological investigation of new compounds acting as ghrelin antagonists.

In 2006, AEterna Zentaris reported first in vivo pharmacological data on the capability of proprietary
'/>"/>

SOURCE AETERNA ZENTARIS INC.
Copyright©2009 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4
Related biology technology :

1. AEterna Zentaris completes management team with the appointment of Chief Medical Officer
2. AEterna Zentaris to Present at Upcoming UBS Global Life Sciences Conference in New York
3. AEterna Zentaris Announces Outcome of Managements Strategic Review
4. AEterna Zentaris to Further Develop Three Follow-up Multi-targeted Cytotoxic Candidates to AEZS-112 as Potential Novel Cancer Treatment
5. AEterna Zentaris Reports First Patients Treated with Anti-Cancer Compound AEZS-108 in Phase 2 Trial in Ovarian and Endometrial Cancers
6. AEterna Zentaris to Present at the Upcoming Roth Capital Partners 20th Annual OC Growth Stock Conference in Dana Point, California
7. Aeterna Zentaris to Announce Fourth Quarter and Full-Year 2007 Financial and Operating Results on March 5, 2008
8. AEterna Zentaris Announces the Departure of SVP, Administrative and Legal Affairs
9. AEterna Zentaris and Paladin Labs Announce Sale and Purchase of Miltefosine Rights
10. Aeterna Zentaris Reports Fourth Quarter and Full-Year 2007 Financial and Operating Results
11. Aeterna Zentaris Begins Second Phase 3 Trial of Cetrorelix for Benign Prostatic Hyperplasia

Post Your Comments:

(Date:6/19/2013)... NC (PRWEB) June 19, 2013 ... eclinical commerce network for clinical trials, today announced ... at DIA 2013 (booth #2000) in Boston, June ... the industry’s first and only fully configurable, cloud-based ... ClinPay®, the flagship module within Clinverse’s eClinical Commerce ...

(Date:6/19/2013)... June 19, 2013 MO BIO Laboratories, ... other challenging microbial nucleic acid purification, announces the ... for extraction of pure protein from all soil ... with the 20 th anniversary of the ... (Photo: http://photos.prnewswire.com/prnh/20130619/LA32633 ) ...

(Date:6/19/2013)... CLEVELAND , June 19, 2013 NineSigma ... announced that a year following its launch, NineSights.com ... and a focal point for the worldwide community of ... to climate and environmental sustainability experts, NineSights stands out ... broad range of scientific and technical disciplines, all vetted ...

(Date:6/19/2013)... Today DuPont Executive Vice President James ... in the greatest challenge facing our time – ensuring ... Borel spoke at the International Food and Agribusiness ... need for students to contribute their time and talents ... reached in collaboration with others. , “Food is one ...

Breaking Biology Technology:Clinverse, Inc. Exhibiting and Showcasing Its Technology at DIA 2013 2 MO BIO Laboratories, Inc. launches the first kit for protein extraction from soil 2 NineSigma Evolves Global Open Innovation through Social Media Platform, NineSights 2 NineSigma Evolves Global Open Innovation through Social Media Platform, NineSights 3 DuPont Leader Calls for New Generation of Food Visionaries to Fight Hunger 2

[0] Clinverse, Inc. Exhibiting and Showcasing Its Technology at DIA 2013 [0] MO BIO Laboratories, Inc. launches the first kit for protein extraction from soil [0] NineSigma Evolves Global Open Innovation through Social Media Platform, NineSights [0] DuPont Leader Calls for New Generation of Food Visionaries to Fight Hunger

... K. H. Valkonen*, N. Marttinen*, H.-L. Malinen*, V.-P. Jaakola** and , ... , * Biotechnology Laboratory, REDEC of Kajaani, University ... ** Department of Biological and Environmental Science, University of Jyvskyl, , ... , Introduction , ...

... Contributed by Philip W Miller, Waltraud I Dunn, and Robert R Schmidt, , ... FL 32611 USA , ... , Introduction , ... elucidate the pre- , and posttranslational mechanisms that regulate ...

... Introduction , ... or probes in genetic analysis. Quality control of these preparations ... electrophoresis or HPLC, but these , methods may ... not provide desired quantitative precision or automation. Capillary electrophorsis , ...

Purification and Characterization of beta-Lactoglobulin Genetic Variants A and B Using Preparative Electrophoresis and Isoelectric Focusing Preparative Nondenaturing Gel Electrophoresis to Purify NADP-Specific Glutamate Dehydrogenase From Chlorella, Rev B Oligonucleotide Purity Analysis by Capillary Electrophoresis

(Date:6/19/2013)... The Microbial Diversity Course at the Marine Biological ... a Milestones in Microbiology site by the American ... in Microbiology program recognizes institutions and the scientists ... toward advancing the science of microbiology. A ... site is scheduled for Saturday, June 22, 2013, ...

(Date:6/19/2013)... , June 19, 2013 MedNet Solutions ... clinical study management systems, is pleased to announce its ... held June 23-27 in Boston . ... a recognized leader in cloud-based eClinical solutions, has exhibited ... be showcasing iMedNet™ EDC , MedNet,s ...

(Date:6/19/2013)... 19, 2013 New York College of Health Professions ... Patent and Trademark Office for detecting biometric changes through ... guards have been injured, attacked or killed. ... the Intellectual Properties Agreements of New York College of ... of New York College says, ...

Breaking Biology News(10 mins):Microbial diversity course designated as a 'Milestones in Microbiology' site 2 MedNet Solutions To Spotlight iMedNet EDC At The 49th DIA Annual Meeting 2 New Technology Using Biometrics Detects If Security Guards Are Attacked, Injured Or Killed 2 New Technology Using Biometrics Detects If Security Guards Are Attacked, Injured Or Killed 3 New Technology Using Biometrics Detects If Security Guards Are Attacked, Injured Or Killed 4

[0] Microbial diversity course designated as a 'Milestones in Microbiology' site [0] MedNet Solutions To Spotlight iMedNet EDC At The 49th DIA Annual Meeting [0] New Technology Using Biometrics Detects If Security Guards Are Attacked, Injured Or Killed

... from Huntsman Cancer Institute (HCI) at the University ... to identify cancer-causing rearrangements of genetic material called ... of the method and the research results appear ... Molecular Medicine journal. Many cancers result from ...

... diseases might soon have another warrior to contend with, thanks ... of Illinois. The new antibiotic, an analog of the widely ... boon to the dairy industry as a treatment for bovine ... product of bacteria resident in the cow,s udder. It helps ...

... may have discovered how memories are encoded in ... strengthened synaptic connections among neurons. However components of ... while memories can last a lifetime. Based ... lead researcher Jack Tuszynski, his graduate student Travis ...

Cached Biology News:Beyond the microscope: Identifying specific cancers using molecular analysis 2 New antibiotic could make food safer and cows healthier 2 New antibiotic could make food safer and cows healthier 3

Beyond the microscope: Identifying specific cancers using molecular analysis New antibiotic could make food safer and cows healthier University of Alberta led research may have discovered how memories are encoded in our brains

...

Caliper offers a wide array of standard LabChip products designed to be used in combination with our AMS 90 and LabChip 3000 microfluidic platforms....

Experion StdSens chips are the microfluidic chips used to perform standard-sensitivity RNA analysis (nanogram levels) with the Experion automated electrophoresis system. Each chip has the capacity to...

...

Biology Products:

SYBR Gold nucleic acid gel stain*10,000X concentrate in DMSO* from Molecular Probes (Invitrogen)Fluorogenic Chip, 4-Sipper from Caliper Life Sciences Experion RNA StdSens Chips, 10 from Bio-Rad MiniMACS Separation Unit from Miltenyi Biotec