Navigation Links
AEterna Zentaris: Lead Investigator for Cetrorelix Trials in BPH Wins Best Poster Presentation Award at European Association of Urology Meeting in Milan
Date:4/30/2008

eek 52, 54, 78 and 80 will be followed up to Week 90.

A second, similarly designed multi-center Phase 3 efficacy study, being led by Prof. Frans M.J. Debruyne, M.D., Ph.D., from The Netherlands, will enroll approximately 400 patients in Europe. The third Phase 3 trial scheduled to start shortly, is an open-label, single-armed multi-center safety study involving approximately 500 patients in both North America and Europe, and is being led by Joel Kaufman, M.D., Associate Clinical Professor of Urology, University of Colorado School of Medicine, Denver, Colorado, and Urology Research Options, Aurora, Colorado.

The primary endpoint for both North American and European efficacy studies is the change in I-PSS between baseline and Week 52. Other efficacy endpoints include additional measures of BPH-symptom progression and the need for BPH-related surgery. Safety endpoints include changes in sexual function. Other important endpoints include plasma changes in levels of testosterone, and assessment of other adverse events.

The cetrorelix Phase 3 program is based on comprehensive clinical practice guidelines to ensure quality control, including input from expert advisors on study design, publishing results in peer-reviewed journals and discussion of the studies with regulatory agencies.

Benign Prostatic Hyperplasia

Benign prostatic hyperplasia (BPH) is one of the most common diseases of aging men - affecting more than 20 million men in the United States - but its etiology is far from being completely understood. Data from ongoing research suggest BPH and its associated lower urinary tract symptoms (LUTS) are more complex conditions than once thought. While previous research on BPH etiology tended to focus on testosterone and other hormones, more recent research suggests other factors may play a greater role in the development of BPH and LUTS - including inflammation, various growth factors, and adrenoreceptors.

BPH-associated LUTS inc
'/>"/>

SOURCE AETERNA ZENTARIS INC.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related biology technology :

1. AEterna Zentaris Partner, Spectrum, Provides Update on Ozarelix in Benign Prostatic Hyperplasia
2. AEterna Zentaris Completes Patient Recruitment for First Phase 3 Efficacy Trial with Cetrorelix in Benign Prostatic Hyperplasia
3. AEterna Zentaris Announces Changes to its Management Team
4. AEterna Zentaris and Paladin Labs Complete Sale and Purchase of Miltefosine Rights
5. Aeterna Zentaris Begins Second Phase 3 Trial of Cetrorelix for Benign Prostatic Hyperplasia
6. Aeterna Zentaris Reports Fourth Quarter and Full-Year 2007 Financial and Operating Results
7. AEterna Zentaris and Paladin Labs Announce Sale and Purchase of Miltefosine Rights
8. AEterna Zentaris Announces the Departure of SVP, Administrative and Legal Affairs
9. Aeterna Zentaris to Announce Fourth Quarter and Full-Year 2007 Financial and Operating Results on March 5, 2008
10. AEterna Zentaris to Present at the Upcoming Roth Capital Partners 20th Annual OC Growth Stock Conference in Dana Point, California
11. AEterna Zentaris Reports First Patients Treated with Anti-Cancer Compound AEZS-108 in Phase 2 Trial in Ovarian and Endometrial Cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... June 17, 2014 Using microscopic polymer light ... gases, researchers at MIT,s Quantum Photonics Laboratory have ... in the parts-per-billion range. Optical sensors are ideal ... high signal-to-noise ratio, compact, lightweight nature, and immunity ... sensors had been developed before, the MIT team ...
(Date:7/10/2014)... extremely challenging because there are many genetic variants that ... Now investigators reporting in the July 3rd issue of ... describe a strategy that may help reveal how such ... environmental exposures to affect the development of the nervous ... predispose individuals to schizophrenia. , The work takes ...
(Date:7/10/2014)... our laptops and electric vehicles could store more energy ... help of a sponge-like silicon material. , Researchers ... used in one of the battery,s electrodes, as silicon ... of graphite. A paper describing the material,s performance as ... Nature Communications . , "Silicon has long been sought ...
(Date:7/10/2014)... shelled out for crude 3-D glasses, polarized glasses, ... These basic devices, used to trick the brain ... be rendered obsolete with the introduction of new ... , TAU doctoral students Yuval Yifat, Michal Eitan, ... based on nanoantennas that could be used for ...
Breaking Biology Technology:Swell new sensors 2New strategy could uncover genes at the root of psychiatric illnesses 2Silicon sponge improves lithium-ion battery performance 2Silicon sponge improves lithium-ion battery performance 3Projecting a 3-dimensional future 2Projecting a 3-dimensional future 3
... Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN ) ... SCORPION(TM) multispecific therapeutic technology at the 100th Annual ... (AACR) in Denver. The data presented demonstrated the ... SCORPION molecule, its differentiation from monospecific approaches, and ...
... demonstrates company,s commitment to sustainabilityLAS VEGAS, April 22 ... commitment to protecting tomorrow today through its sustainability ... Region for Bayer CropScience, presented Tom Lovelace, United ... million endowment over the next four years to ...
... Cohen to be inducted into National Academy of Sciences for ... Sir Philip Cohen of Scotland,s University of Dundee ... (NAS) during its 146th annual meeting on Saturday, April 25 ... in original scientific research. Sir Philip is one of only ...
Cached Biology Technology:Trubion Presents Preclinical Data on Its SCORPION(TM) Multispecific Therapeutics at the 2009 American Association of Cancer Research Annual Meeting 2Trubion Presents Preclinical Data on Its SCORPION(TM) Multispecific Therapeutics at the 2009 American Association of Cancer Research Annual Meeting 3Trubion Presents Preclinical Data on Its SCORPION(TM) Multispecific Therapeutics at the 2009 American Association of Cancer Research Annual Meeting 4Bayer CropScience Donates $1.1 Million to United Fresh Research & Education Foundation to Create the Center for Global Produce Sustainability 2Bayer CropScience Donates $1.1 Million to United Fresh Research & Education Foundation to Create the Center for Global Produce Sustainability 3Bayer CropScience Donates $1.1 Million to United Fresh Research & Education Foundation to Create the Center for Global Produce Sustainability 4United States Recognizes Leading Scottish Scientist for Disease Research 2
(Date:7/10/2014)... Oregon State University have developed a small, portable and ... all over the world better understand the radiation around ... it poses a health risk. , The device was ... nuclear incident in Fukushima, Japan, in 2011, when many ... were being exposed to and whether their homes, food, ...
(Date:7/10/2014)... or GOES-West satellite spotted smoke over the U.S. ... Northwestern Territories. , At 1200 UTC (8 a.m. ... image of the brownish-colored haze created by forest ... the way into South Dakota. This image was ... Goddard Space Flight Center, Greenbelt, Md. , ...
(Date:7/10/2014)... NOAA and its research partners predict that western Lake ... toxic blue-green algae, during the 2014 bloom season in ... be smaller than last year,s intense bloom, and considerably ... will vary across the lake,s western basin and are ... how far it spreads. , Harmful algal blooms ...
Breaking Biology News(10 mins):Sophisticated radiation detector designed for broad public use 2Sophisticated radiation detector designed for broad public use 3NOAA, partners predict significant harmful algal bloom in western Lake Erie this summer 2NOAA, partners predict significant harmful algal bloom in western Lake Erie this summer 3
... cell phones have dramatically changed the way we share the ... friends and family. Now, the imaging sensor chips that form ... the California Institute of Technology (Caltech) transform the way cell ... "smart" petri dish. Dubbed ePetri, the device is ...
... D.C.-- The world,s largest celebration of science and ... return to Washington, D.C., April 28-29, 2012. For ... will participate with hands-on experiments. At Carnegie,s booth ... a real diamond produced by our high pressure ...
... Ore. At the end of the last Ice Age, ... scientists have long hypothesized that the source was CO 2 ... study using detailed radiocarbon dating of foraminifera found in a ... the Northeast Pacific was not an important reservoir of carbon ...
Cached Biology News:Caltech engineers build smart petri dish 2Caltech engineers build smart petri dish 3Carnegie partners with USA Science & Engineering Festival for second year 2Carnegie partners with USA Science & Engineering Festival for second year 3Rising CO2 levels at end of Ice Age not tied to Pacific Ocean 2Rising CO2 levels at end of Ice Age not tied to Pacific Ocean 3
... a fluorescein-conjugated jetSI-ENDO (excitation ... 520 nm), the powerful siRNA ... used to determine the transfection ... delivery and trafficking of siRNAs. ...
... and Tissue Staining Kits are intended for ... of histological and cytological specimens. These kits ... manufactured by either R&D Systems or by ... the formation of the Avidin-Biotin Complex (ABC) ...
... wide range of hands-on techniques that are ... all areas of protein chemistry and molecular ... illustrates just how valuable this book will ... introduce the theoretical background of a method ...
... Performance The TSQ Quantum Ultra defines ... bioanalytical and environmental analysis. It features ... APCI probes, a titanium skimmer with superior ... and sensitivity. Its redesigned ion transfer ...
Biology Products: