Navigation Links
AEgis Technologies Announces Official Launch of ADME WorkBench Software for Pharmacokinetics Prediction

Huntsville, Alabama (PRWEB) September 16, 2013

The AEgis Technologies Group, Inc., is pleased to announce the release of ADME WorkBench, a new software product for pharmacokinetic prediction. Newly available in 2013, ADME Workbench is a versatile software application providing flexible, robust pharmacokinetic modeling by integrating state-of-the-art absorption, distribution, metabolism and excretion methods. Designed for research applications in pharmacology and toxicology, ADME WorkBench supports pharmacokinetic prediction from available in vitro and/or in vivo data for drugs and environmental chemicals. The ADME WorkBench user interface offers a highly optimized workflow for predictive pharmacokinetics, while allowing ample flexibility to adapt to specific research needs. The pharmacokinetic models used in ADME WorkBench are based on research resulting from the PhRMA CPCDC Initiative on Predictive Models of Human Pharmacokinetics, and described in a series of articles published in the Journal of Pharmaceutical Sciences in 2011. Extension of the models and implementation in ADME WorkBench has resulted from an ongoing scientific collaboration between Dr. Patrick Poulin and AEgis Technologies.

"We are excited to provide drug discovery and toxicology scientists a powerful new platform implementing a wide variety of predictive PK techniques, and which doesn't depend on black-box proprietary models," said Director of acslX Product Development Conrad Housand. "This release is the culmination of over two years of collaboration, development and testing, and we look forward to incorporating even more capabilities in the coming months."

Current ADME Workbench capabilities include:

  • Support for several state-of-the-art PK prediction techniques, including whole-body and lumped physiologically-based pharmacokinetic (PBPK) models, and allometry based on the Wajima approach
  • PBPK models which include advanced multi-compartment GI uptake models, support for both linear and nonlinear kinetics, and an advanced liver model
  • Support for end-user customization of any of the provided PBPK models
  • A choice of prediction methods depending on availability of preclinical data determined either in vitro and/or in vivo in single or multiple species
  • Ability to integrate values of ADME parameters predicted from a broad range of methods
  • Ability to simulate a single compound or multiple compounds in batch mode
  • Simulation of tissue concentration at the macro level (whole organ) and micro level (cell, interstitial fluid) either for the bound or unbound drug condition

About AEgis Technologies Group

AEgis Technologies is a privately held small business headquartered in Huntsville, Alabama, USA, that provides advanced technology and expert consulting services to industries throughout the world. AEgis specializes in modeling & simulation (M&S) and micro/nanoscale technology development. The company’s M&S products and services include software for the pharmaceutical/risk assessment, industrial process, automotive, and military/aerospace markets. AEgis’ Nanogenesis Division excels in advancing cutting edge micro and nanoscale technologies from concept to deployment with applications ranging from defense to energy to biotechnology.

AEgis has enjoyed steady growth with revenues increasing to $65 million in sales and employment of 325+ professionals. AEgis has been instrumental in the acceptance of M&S as a profession, as a graduate program of study among many colleges and universities and in the creation of an M&S standards and professional certification across the international M&S professional community-of-practice. Since its founding in 1989, AEgis is committed to honesty and integrity and was recognized for its honorable business practices by receiving the Better Business Bureau’s Torch Ethics Award. The company’s highly skilled work force is dedicated to building lasting relationships and providing superior products and services to our customers.

AEgis corporate headquarters are located at 410 Jan Davis Drive, Huntsville, AL 35806; Tel: 256-922-0802; Fax: 256-922-0904; Web: and

Follow us on Twitter @admewb

acslX and ADME WorkBench are a trademarks of The AEgis Technologies Group, Inc.

Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related biology technology :

1. AspenBio to Present at 2012 Aegis Healthcare Conference
2. Trovagene, Inc. Announces Full Exercise of Over-Allotment Option by Aegis Capital Corp.
3. Discovery Channel MythBuster Star Jaime Vendera First Person on Record to Break a Glass with His Voice Endorses UV-Aid by UV Technologies, LLC
4. Adaptive Biotechnologies Receives $2.53 million Phase II SBIR to Develop Test to Identify Cancer Patients at Risk of Death by Infection after Cord Blood Transplants
5. Genia Technologies, Columbia University, and Harvard University Awarded $5.25 Million Grant from NIH to Accelerate the Development of NanoTag DNA Sequencing Technology
6. SPIE Launches New Symposium to Foster Dual-Use Sensor Technologies
7. Surfacing for Success: Emergent Technologies and KODE Biotech Join Forces to Expand Markets for Platform Technology
8. Cardiovascular Drug Delivery - Technologies, Markets and Companies - Updated 2012 Report
9. Former Life Technologies and BD Biosciences Executive John L. "Kip" Miller Joins Solulinks Board of Directors
10. HealthCare, Technology Briefing: Market Movers for the Week - Technologies-Scan Corp, GNC, Galena Biopharma, Immunomedics, Amarin
11. Bayer CropScience and MS Technologies Receive Approval for Balance GT Soybean Technology in the United States
Post Your Comments:
(Date:12/1/2015)... SAN DIEGO , Dec. 1, 2015 /PRNewswire/ ... that uses allogeneic stem cells for cardiovascular indications, ... clinical trial protocol based on recommendations from a ... leaders and its Scientific Advisory Board members ... boards analyzed preliminary Phase IIa safety and efficacy ...
(Date:12/1/2015)... Cepheid (Nasdaq: CPHD ) today announced ... Jaffray Healthcare Conference in New York City ... its outlook for the fourth quarter of 2015 and ... longer term business model expectations. John Bishop ... to be the fastest growing company of the major ...
(Date:11/30/2015)... ... 30, 2015 , ... Global Stem Cells Group ... from Central America and abroad for the first Iberoamerican Convention on Aesthetic Medicine, ... 2016. Testart will present and discuss new trends in anti-aging stem cell treatments, ...
(Date:11/30/2015)... MONTREAL , Dec. 1, 2015 /PRNewswire/ - BioAmber Inc. (NYSE: ... that it has joined the American Business Act on Climate ... economy that are standing with the Obama Administration to demonstrate ... for a strong outcome to the COP21 Paris ... . --> Sarnia, Canada . ...
Breaking Biology Technology:
(Date:10/29/2015)... Calif. , Oct. 29, 2015  The J. ... new report titled, "DNA Synthesis and Biosecurity: Lessons Learned ... the Department of Health and Human Services guidance for ... in 2010. --> ... it also has the potential to pose unique biosecurity ...
(Date:10/29/2015)... , Oct. 29, 2015  Connected health pioneer, ... driving the explosion of technology-enabled health and wellness, and ... new book, The Internet of Healthy Things ... sensors or smartphones even existed, Dr. Kvedar, vice president, ... of health care delivery, moving care from the hospital ...
(Date:10/27/2015)... , Oct. 27, 2015 In the present ... of concern for various industry verticals such as banking, ... to the growing demand for secure & simplified access ... ,sectors, such as hacking of bank accounts, misuse of ... equipment such as PC,s, laptops, and smartphones are expected ...
Breaking Biology News(10 mins):