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ACT Secures Patent to Generate Embryonic Stem Cells Without Embryo Destruction
Date:2/23/2011

MARLBOROUGH, Mass., Feb. 23, 2011 /PRNewswire/ -- Advanced Cell Technology, Inc. ("ACT"; OTC Bulletin Board: ACTC), a leader in the field of regenerative medicine, announced today that it has been issued a patent on its "single-blastomere" technique.  Patent Number 7,893,315 broadly covers ACT's proprietary single-blastomere technology that provides a non-destructive alternative for deriving human embryonic stem cell (hESC) lines.  

"Of the more than 150 patents and patent applications related to stem cell therapy and regenerative medicine that ACT owns or licenses, this patent on our single-blastomere technology is one of the most significant," stated Gary Rabin, ACT's interim chairman and CEO.  "It will help us accelerate our progress on a number of fronts, including deriving embryonic stem cells which meet the regulatory standards of the European Medicines Agency and the US Food and Drug Administration, using the single-blastomere technology.  We are currently developing a collaboration for creating banks of these cells using our proprietary technique with the United Kingdom's Roslin Cells.  This is an example of the type of potentially revenue-generating future partnership that we think this IP (intellectual property) protection could help facilitate."

The single-blastomere technology uses a one-cell biopsy approach similar to pre-implantation genetic diagnosis (PGD), which is widely used in the in vitro fertilization (IVF) process and does not interfere with the embryo's developmental potential.  The stem cells generated using this approach are healthy, completely normal, and differentiate into all the cell types of the human body, including insulin-producing cells, blood cells, beating heart cells, cartilage, and other cell types of therapeutic importance.  The safety record for one-cell biopsy as part of PGD now has a 1
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SOURCE Advanced Cell Technology, Inc.
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