Navigation Links
A simple therapy for brain injury
Date:6/26/2008

Severe brain injury due to blunt force trauma could be reduced by application of a simple polymer, Polyethylene glycol or PEG, mixed in sterile water and injected into the blood stream as reported in BioMed Central's Journal of Biological Engineering.

Andrew Koob and Richard Borgens from Purdue University, Indiana, performed experiments in rats which showed that PEG was effective in limiting damage if administered within four hours after the head injury. However, if treatment was delayed for a further two hours, the beneficial effects were lost. During the experiments, rats were injured with a falling weight and then PEG was administered fifteen minutes, two hours, four hours or six hours later. The authors then carried out a series of behavioural tests on the rats to determine the effectiveness of the PEG treatment.

According to Borgens "These data suggest that PEG may be clinically useful to victims of traumatic brain injury if delivered as rapidly as possible after an injury". Such a treatment could feasibly be carried out at the scene of an accident where PEG could be delivered as a component of IV fluids thus reducing long term brain injury.


'/>"/>

Contact: Graeme Baldwin
graeme.baldwin@biomedcentral.com
44-020-763-14804
BioMed Central
Source:Eurekalert

Page: 1

Related biology technology :

1. Sensitivity Enhancements to Monograms Trofile(TM) Assay Demonstrate Improved Power to Select Patients for CCR5 Antagonist Therapy
2. AMT Makes Important Advance in the Development of its Gene Therapy for Hemophilia B -Company Accesses Technology to Prevent Immune Response
3. Presentation at the 14th International Conference on Prenatal Diagnosis and Therapy Highlights Biocepts I.D.Rh(D) Prenatal Diagnostic
4. Quest PharmaTech Announces Positive Results from Phase I Clinical Trial of its Photodynamic Therapy for Actinic Keratosis
5. Investigational Studies Highlight Potential Utility of Zevalin(R) (Ibritumomab Tiuxetan) Radioimmunotherapy in Stem Cell Transplantation for Non-Hodgkins Lymphoma
6. Ipsogen Launches MapQuant Dx(TM) Genomic Grade Test to Identify Breast Cancer Patients who Benefit From Chemotherapy
7. First Taxane-Based Non-Anthracycline Containing Chemotherapy in Combination With Herceptin (TCH) for HER2 Positive Early Breast Cancer Patients Obtains Approval From the FDA
8. American Urological Association (AUA) Clinical Guidelines Recognizes Cryotherapy as Treatment Option for Prostate Cancer Patients
9. FDA Clears New Applicators for Endometrial Cancer Treatment With Xofts Axxent(R) Electronic Brachytherapy System
10. New Patient Satisfaction Study With budesonide/formoterol Combination Therapy and fluticasone/salmeterol Combination Therapy in Adults With Asthma
11. Sangamo BioSciences Announces Presentation of Phase 1 Data of ZFP Therapeutic at International Society for Cellular Therapy (ISCT) Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2016)... New York , May 4, 2016 ... by Transparency Market Research "Metabolomics Market - Global Industry ... 2024", the metabolomics market is anticipated to expand at ... reach USD 2,494.8 million by 2024. Metabolomics ... as metabolites, within cells, biofluids, tissues or organisms. Together, ...
(Date:5/4/2016)... ... May 04, 2016 , ... Nutrafol®, a first-to-market smart-supplement ... hormonal and stress related hair loss. With patent-pending formulas for both female hair ... leaders in the medical and salon channels nationwide. , Dermatologists, Plastic Surgeons ...
(Date:5/3/2016)... ... May 03, 2016 , ... ... skill-building and compliance training platform on mobile devices, today released a new interactive ... Requirements for Medical Devices. The course is essential for owners or operators of ...
(Date:5/3/2016)... , ... May 03, 2016 , ... ... at Boston CEO 2016 on May 31st and June 1st at The Four ... for leading executives in the life sciences, offering exclusive access to key decision ...
Breaking Biology Technology:
(Date:4/28/2016)... , April 28, 2016 Infosys ... (NYSE: INFY ), and Samsung SDS, a global ... that will provide end customers with a more secure, fast ...      (Logo: http://photos.prnewswire.com/prnh/20130122/589162 ) , ... but it also plays a fundamental part in enabling and ...
(Date:4/15/2016)... , April 15, 2016  A new partnership ... more accurate underwriting decisions in a fraction of ... competitively priced and high-value life insurance policies to ... With Force Diagnostics, rapid testing (A1C, ... data readings (blood pressure, weight, pulse, BMI, and ...
(Date:3/31/2016)... , March 31, 2016  Genomics firm Nabsys ... founding CEO, Barrett Bready , M.D., who returned ... of the original technical leadership team, including Chief Technology ... of Product Development, Steve Nurnberg and Vice President of ... to the company. Dr. Bready served as ...
Breaking Biology News(10 mins):