Navigation Links
A non-invasive method to track Huntington's disease progression
Date:9/17/2012

Huntington's disease is a fatal, inherited neurodegenerative disorder caused by a mutation in the gene encoding huntingtin. Expresion of mutant huntingtin (mHTT) protein is correlated with the onset and progression of the disease and new therapies are being developed to reduce the expression of mHTT. In order to evaluate these new therapies, researchers need to be able to quantify the amount of mHTT in a particular patient; however, non-invasive quantification of mHTT isn't currently possible. In this issue of the Journal of Clinical Investigation, researchers led by Sarah Tabrizi at University College London report that mHTT can be detected in immune cells isolated during a normal blood draw. mHTT levels were significantly correlated with disease symptom severity, indicating that this test could serve as a non-invasive biomarker for Huntington's disease.


'/>"/>
Contact: Jillian Hurst
press_releases@the-jci.org
Journal of Clinical Investigation
Source:Eurekalert

Page: 1

Related biology technology :

1. Exosome Diagnostics Presents Data at American Urology Association Demonstrating Potential Utility of Urine Exosomes to Non-invasively Detect and Manage Prostate Cancer
2. DermTechs Non-invasive Melanoma Detection Assay Poised to Enter Clinical Validation Study
3. Lifeline Biotechnologies Receives Patent for Methods to Collect and Analyze Breast Thermal Data to Determine Suspect Conditions
4. Published Findings In Human Gene Therapy Methods Journal Demonstrate Cardiums New Catheter-Based Method Significantly Boosts Gene Delivery To The Heart
5. DNA2.0 Patents Key Method for Synthesizing Bioplastic Polymer
6. OncoSec Announces Issuance of New Patent for Method of Use
7. Eutropics Pharmaceuticals Receives U.S. Patent for Novel Diagnostic Method
8. New UCLA method quickly IDs nanomaterials that can cause oxidative damage to cells
9. Fabrication method can affect the use of block copolymer thin films
10. X-BODY BioSciences to Present Novel Methods of Selecting for Antibodies Against Targets on Live Cells at CHIs Protein Engineering Summit
11. New method yields insulin-producing pancreatic cell clusters
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/3/2016)... 3, 2016  Dr. Thomas P. McHugh , ... The Woodlands, Texas , now offers SculpSure, ... treated fat cells in just 25-minutes, leaving a slimmer ... percent of Americans report feeling bothered by excess weight ... procedures are a growing industry. This innovative new approach ...
(Date:5/2/2016)... ... May 02, 2016 , ... StarNet Communications Corp, ( http://www.starnet.com/ ) a leading ... Secure Remote Desktop modules to its flagship X-Win32 PC X server. The new ... to the user’s PC over encrypted SSH. , Traditionally, users of PC X servers ...
(Date:4/29/2016)... , April 29, 2016 ... by Transparency Market Research "Separation Systems for Commercial ... Growth, Trends, and Forecast 2015 - 2023", the ... at US$ 10,665.5 Mn in 2014 and is ... from 2015 to 2023 to reach US$ 19,227.8 ...
(Date:4/28/2016)... , April 28, 2016 The ... and Brayton Cryocoolers), Service (Technical Support, Product Repairs & ... - Global Forecast to 2022", published by MarketsandMarkets, the ... Billion by 2022, at a CAGR of 7.29% between ... data Tables and 94 Figures spread through 159 Pages ...
Breaking Biology Technology:
(Date:3/21/2016)... 2016 Unique technology combines ... superior security   Xura, Inc. ... secure digital communications services, today announced it is working ... enterprise customers, particularly those in the Financial Services Sector, ... authentication within a mobile app, alongside, and in combination ...
(Date:3/15/2016)... York , March 15, 2016 ... market report published by Transparency Market Research "Digital Door Lock ... and Forecast 2015 - 2023," the global digital door lock ... 731.9 Mn in 2014 and is forecast to grow at ... Growth of micro, small and medium enterprises (MSMEs) across the ...
(Date:3/14/2016)... , Allemagne, March 14, 2016 ... http://www.apimages.com ) - --> - Renvoi : ... - --> --> ... solutions biométriques, fournit de nouveaux lecteurs d,empreintes digitales ... LF10 de DERMALOG sera utilisé pour produire des ...
Breaking Biology News(10 mins):