Navigation Links
A breath of fresh air for detecting vitamin B12 deficiency
Date:6/22/2011

t we breathe out, the researchers labelled the administered propionate with a stable isotope of carbon, which would then be exhaled in the breath as labelled carbon dioxide.

The initial testing of the B12 breath test conducted measurements on subjects with chronic pancreatitis, Crohn's disease, and small intestinal bacterial overgrowth, as well as patients over 65 all of which are associated with a higher incidence of vitamin B12 deficiency.

After fasting and not smoking for 8 hours, the study subjects were orally administered 50 mg of propionate and then tested every 10 minutes for the first hour and every 15 minutes for the second hour, with the best diagnostic accuracy appearing to be the 10 and 20 minute intervals.

To ascertain the accuracy of the breath test, the obtained vitamin B12 levels were compared with several blood compounds that are currently used to ascertain vitamin B12 deficiency.

The authors concluded that the results from their study indicate that the vitamin B12 breath test is a non-invasive, sensitive, specific, and reproducible diagnostic test to detect vitamin B12 deficiency.

Lead author Dr. David Wagner said, "Initially, larger studies must be conducted including treatment of B12 deficient subjects showing resolution of the abnormal breath test results. If these results are positive, FDA approval with many study centres will need to be conducted.

"With adequate funding, the test could be approved in 3-5 years."


'/>"/>

Contact: Michael Bishop
michael.bishop@iop.org
01-179-301-032
Institute of Physics
Source:Eurekalert

Page: 1 2

Related biology technology :

1. Researchers develop living, breathing human lung-on-a-chip
2. Rock-breathing bacteria could generate electricity and clean up oil spills
3. ChemImage and Next Breath Structure Partnership to Validate Bioequivalence Testing for Nasal Spray Suspensions
4. From seawater to freshwater with a nanotechnology filter
5. A Fresh Approach to Marketing: Dr. Fresh™, Inc. Goes Guerilla With Internet-Based Campaigns
6. Bayer CropScience Donates $1.1 Million to United Fresh Research & Education Foundation to Create the Center for Global Produce Sustainability
7. New Health Retreat Gives a Fresh Attitude Towards Disease Prevention
8. Natures Premium(R) Brand First Fresh Pork in North America to Carry DNA TraceBack(R) Seal of Authenticity
9. New technology could inspire brain implant for detecting and treating seizures
10. Radar shows promise for detecting concussions in athletes and soldiers
11. Simple test could offer cheap solution to detecting landmines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)...  Vermillion, Inc. (Nasdaq:   VRML), a bio-analytical solutions ... the Company closed its previously announced private placement ... W. Schuler , Birchview Fund LLC and several ... offering expenses.  The proceeds will be used for ...
(Date:12/24/2014)... 2014 “Preparative & Process Chromatography ... Consumables (Columns, Solvents, Buffers, Valves, Guages, Seals), Accessories, ... - Forecasts to 2019” provides a detailed overview ... market trends, and strategies impacting the preparative and ...
(Date:12/24/2014)... Earlier this year in a June 24 international conference ... Cell Technology Center, LLC ( ASCTC ) focused attention on ... tissue stem cells. His title “Asymmetric Self-Renewal by Distributed ... embodied the essence of his message to congress participants. ...
(Date:12/24/2014)... On Friday, December 19, 2014, President Obama ... Resolution Appropriations Act of 2015, which for the first ... through the Congressionally Directed Medical Research Programs (CDMRP) administered ... (HA), working in conjunction with its allies on Capitol ...
Breaking Biology Technology:Vermillion Announces Closing of Equity Financing 2Vermillion Announces Closing of Equity Financing 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 2Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 3Adult Stem Cell Technology Center, LLC’s Director Sherley's Address on What’s Holding Back Regenerative Medicine Featured on Omics Group Website 4Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2
... fighting to stay on budget as the first quarter of 2009 came to ... a field once thought immune to the troubles of the rest of the ... ... March 23, 2009 -- As the first quarter of 2009 came to a ...
... Trubion Pharmaceuticals, Inc. (Nasdaq: TRBN ... its SCORPION(TM) multispecific therapeutic technology at the 100th ... Research (AACR) in Denver. The data presented demonstrated ... CD79BxDR SCORPION molecule, its differentiation from monospecific approaches, ...
... Do winery tasting rooms really help generate sales for ... Innovation Centre almost half of winery tasting room visitors ... visit. , "This research proves that the tasting room ... in future sales," said Dr. Isabelle Lesschaeve, research director, ...
Cached Biology Technology:The MedZilla Report: March 2009 Employment Outlook for Biotech/Pharma/Health 2The MedZilla Report: March 2009 Employment Outlook for Biotech/Pharma/Health 3The MedZilla Report: March 2009 Employment Outlook for Biotech/Pharma/Health 4Trubion Presents Preclinical Data on Its SCORPION(TM) Multispecific Therapeutics at the 2009 American Association of Cancer Research Annual Meeting 2Trubion Presents Preclinical Data on Its SCORPION(TM) Multispecific Therapeutics at the 2009 American Association of Cancer Research Annual Meeting 3Trubion Presents Preclinical Data on Its SCORPION(TM) Multispecific Therapeutics at the 2009 American Association of Cancer Research Annual Meeting 4Setting the Benchmark for Winery Tasting Room Research: An Emerging Region Gets a Global Perspective 2
(Date:12/17/2014)... 16, 2014  Automation is fundamentally transforming the travel experience ... borders. Over the past decade, ePassports, biometric readers, and ... process through border control via eGates and Automated Passport ... seaports, and land borders across the globe. ...
(Date:12/11/2014)... and Markets , http://photos.prnewswire.com/prnh/20130307/600769 ... the addition of the "Biometrics Market in the ... One major trend emerging in this market is ... is important to upgrade biometric solutions to the latest ...
(Date:12/11/2014)... Dec. 10, 2014  That blood pressure plays a role in ... – the medical term for high blood pressure – was ... the inflatable cuff that,s used in measuring blood pressure was ... nothing new about hypertension, its triggers and its effects. In ...
Breaking Biology News(10 mins):Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2Research points to need for new approaches to treatment of high blood pressure 2Research points to need for new approaches to treatment of high blood pressure 3Research points to need for new approaches to treatment of high blood pressure 4
... previously thought to be disordered may in fact have an ... -- according to a study published by researchers at Fox ... Structure (Cell Press). The researchers published ... serves as a means of bringing together molecular signals between ...
... risen sharply in developed countries in the wake of the ... the condition. Foot problems are the most common cause of ... serious complications such as nerve damage and problems with the ... slow-healing wounds and foot ulcers which, if they get infected ...
... the principle of supply and demand at least at the ... proteins, are required at all times. That means most of their ... case in higher organisms. In the simplest case, a transcription factor ... that are regulated in a somewhat more complex manner, on the ...
Cached Biology News:'Disordered' amino acids may really be there to provide wiggle room for signaling protein 2'Disordered' amino acids may really be there to provide wiggle room for signaling protein 3Protective footwear for diabetics at a high-street price 2Protective footwear for diabetics at a high-street price 3The evolution of gene regulation 2The evolution of gene regulation 3