Navigation Links
A New Mechanism for Tau Protein Pathology in Alzheimer's Disease was Presented by Oligomerix, Inc. at the Society for Neuroscience Annual Meeting
Date:11/16/2011

NEW YORK, Nov. 16, 2011 /PRNewswire/ -- Oligomerix, Inc. presented results at the Society for Neuroscience meeting in Washington D.C. which demonstrated that tau protein forms neurotoxic oligomers with a newly discovered enzymatic function. This proteolytic function results in tau's self-fragmentation and in the degradation of other proteins suggesting a mechanism for its neurotoxic mode-of-action. Furthermore, certain tau oligomer species that contained the highest level of activity also proved to be the most toxic to cultured neurons. Tau's enzymatic activity may play a key role in Alzheimer's disease (AD) progression and therefore may represent an important therapeutic intervention point.

James Moe, President and CEO of Oligomerix, Inc., stated, "Recent advances in the field indicate that tau oligomers are involved in Alzheimer's disease progression and inhibit memory formation.  Inhibiting the tau oligomer protease may be an effective intervention for not only improving cognitive function, but also for interrupting disease progression."

The Alzheimer's Association estimates that there are 5.4 million AD sufferers in the US alone that require 14.9 million unpaid caregivers and costs the US economy approximately $183 billion every year.  There are no FDA approved therapeutics that alter the course of disease or slow its progression. Tau protease pathology may represent a new target for slowing or arresting disease progression.

ABOUT OLIGOMERIX

Oligomerix, Inc. is a biopharmaceutical company focused on development of small molecule inhibitors, immunotherapeutic approaches, and biomarkers targeting tau oligomers and their newly discovered proteolytic enzymatic activity.  The Company was founded in 2006 and is located within the Audubon Biomedical Science and Technology Park at Columbia University Medical Center.  The Company is seeking strategic partners to help accelerate its exciting tau protease program.

For more information visit www.oligomerix.com.

Certain matters described in this news release may be forward-looking statements subject to risks and uncertainties that could cause actual results to differ materially from those indicated in the forward-looking statements.  Such risks and uncertainties include, but are not limited to, the risk of dependence on market growth, competition and dependence on government agencies and other third parties for funding contract research and services.

CONTACTS:
Oligomerix, Inc.
Jack Pasini
Chief Commercial Officer
917-912-4088
jpasini@oligomerix.com

Tiberend Strategic Advisors, Inc.
Andrew Mielach, Media
212-827-0020
amielach@tiberend.com


'/>"/>
SOURCE Oligomerix, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related biology technology :

1. Scripps Research team discovers treatable mechanism responsible for often deadly response to flu
2. Oxidation mechanisms at gold nanoclusters unraveled
3. New Research Reveals Mechanism By Which TNFerade(TM) Suppresses Metastases
4. Finding a protective mechanism for retinal cells could save sight
5. Scientists use math modeling to predict unknown biological mechanism of regulation
6. Cellzome Technology Used to Unravel Novel Regulatory Mechanism in Cancer Signaling Pathway
7. Cell Metabolism Publishes Novel TGR5-Mediated Mechanism for the Treatment of Diabetes and Obesity
8. Funxional Successfully Completes Initial Clinical Trial of FX125L, an Anti-Inflammatory Drug With a Novel Mechanism of Action
9. Bionovo Announces Publication of Data on Active Compound and Mechanism of Action for Its Preclinical Cancer Treatment, BN108
10. DNA duplication: A mechanism for survival of the fittest
11. New Insights into the Mechanism of Action of Antipsychotic Drugs
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/18/2016)... (PRWEB) , ... May 18, 2016 , ... ... 1,200 hospitalizations are a direct result of asthma complications.* Costing more than $56 ... the country. , “For too many, the suffering associated with ...
(Date:5/18/2016)... ... May 18, 2016 , ... Ryan Benton was diagnosed with ... in the late teens to early twenties. DMD is a relatively common progressive genetic ... age of 22, Benton’s condition was critical. He met with the founder of the ...
(Date:5/17/2016)... , ... May 17, 2016 , ... ... in animal waste reduction applications, announced today it will be showcasing ManureMagic™ at ... , ManureMagic™ was featured in the Wall Street Journal last year and more ...
(Date:5/17/2016)... ... May 17, 2016 , ... PATH and Laerdal Global ... to bring a feeding cup to market based on a reference design co-developed ... at Seattle Children’s Hospital, thereby ensuring an innovative feeding option for the 7.6 ...
Breaking Biology Technology:
(Date:3/17/2016)... -- ABI Research, the leader in transformative technology ... will reach more than $30 billion by 2021, ... electronics, particularly smartphones, continue to boost the biometrics ... two billion shipments by 2021 at a 40% ... Analyst at ABI Research. "Surveillance is also gearing ...
(Date:3/14/2016)... , Allemagne, March 14, 2016 ... http://www.apimages.com ) - --> - Renvoi : ... - --> --> ... solutions biométriques, fournit de nouveaux lecteurs d,empreintes digitales ... LF10 de DERMALOG sera utilisé pour produire des ...
(Date:3/10/2016)...   Unisys Corporation (NYSE: UIS ) today ... is testing its biometric identity solution at the Otay Mesa ... help identify certain non-U.S. citizens leaving the country. ... help determine the efficiency and accuracy of using biometric technologies ... run until May 2016. --> the United ...
Breaking Biology News(10 mins):