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A New Era in the Application of Lab-on-a-Chip to Rapid Point-of-Care Diagnosis
Date:5/17/2009

HKLife and its subsidiaries. His success and achievements in both academia and bio-commercial endeavors continues to bring HKLife's vision of becoming "the world's leading molecular diagnostics company" closer to fruition. HKLife has pioneered the development of advanced and ground-breaking DNA-based diagnostic technologies and leveraging a unique business model, steered the development of its novel EFADchip technology into a fully-functional platform. Thus, the company has created the impetus to revolutionize the practice of clinical and point-of-care diagnostics and ultimately establish HKLife as a prominent player in driving Asia into the globally competitive biotechnology arena.

The EFADchip technology uses electric field-assisted DNA hybridization to accelerate the detection of biological samples on a single chip. The key differentiator of this technology is the use of a dielectric material for both electric field generation and capture probe DNA immobilization, thus avoiding adverse electrochemical effects that can lead to reduced sensitivity and accuracy of detection. The EFADchip is fabricated using widely available materials and common photolithographic techniques well known in the miniaturized electronics industry, resulting in a structure that is inherently stable under varying ambient conditions.

Type A/H1N1 detection kits are available across three diagnostic technology platforms: VDS makes use of the highly advanced nucleic acid sequence-based amplification - enzyme-linked oligonucleotide capture (NASBA-EOC). The VDS technology has an advantage of not requiring the use of specialized equipment; VetDetect utilizes real-time reverse transcriptase polymerase chain reaction (RT-PCR) and VetScreen employs the conventional gel-based RT-PCR technique. All three platforms are highly sensitive and specific, giving rapid and accurate results within two to four hours.

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