Navigation Links
A CNIO team discovers that senescence also plays a role in embryo development
Date:11/14/2013

beneficial process, whose goal in adult organisms is to eliminate damaged cells", says Serrano, "what happens is that when we get old there are more damaged cells and consequently there is more senescence". In other words, blaming senescence for ageing is like blaming firefighters for fires just because they are always next to a fire.

The two new articles published in Cell offer a new perspective on the concept of senescence. The researchers have not only detected senescence in the embryo: they have also identified the genes that activate and regulate the process, and have studied what happens when they prevent senescence experimentally. To distinguish senescence as a defence mechanism from senescence in normal embryonic development, they term the latter process programmed senescence.

Furthermore, they conclude with a provocative hypothesis: senescence appeared during evolution as a developmental process and, later on, the invention was adapted as a defence mechanism for adult organisms. "Conceptually, we add cellular senescence to the collection of processes that contribute to embryonic development", say the authors in Cell. "This opens up the possibility that cellular senescence originated during evolution as an embryonic tissue-remodelling process, a function that later evolved to become a damage and stress response".

The CNIO authors worked with mouse and human embryos, whilst the CRG team worked with chicken and mouse embryos, and they observed senescence in the three species. They highlight that this "supports the idea that senescence is widespread during the embryonic development of vertebrates".

Embryonic transmutations

Senescence leaves a characteristic chemical signature in cells. CNIO researchers looked for it specifically in two embryo structures: the mesonephros and the endolymphatic sac. The mesonephros is a tissue that functions as a kidney during development and later almost completely disappears; what remai
'/>"/>

Contact: Nuria Noriega
comunicacion@cnio.es
Centro Nacional de Investigaciones Oncologicas (CNIO)
Source:Eurekalert

Page: 1 2 3

Related biology technology :

1. Medical Scientist Discovers an Alternative Treatment for Leukemia Using Alkaline Ionized or Electrolyzed Reduced Drinking Water
2. Rice University discovers that graphene oxide soaks up radioactive waste
3. iDiverse Discovers Yeast Gene that Increases Fuel Ethanol Production Yield
4. deCODE Genetics, in Collaboration with Academic Colleagues, Discovers Three Variants in the Sequence of the Human Genome that Affect the Risk of Thyroid Cancer
5. Trade Show Display Co. GLM Displays Introduces 34 New Trade Show Display Packages & Kits
6. Trade Show Display Co. GLM Displays Launches New “Customer Spotlight” Campaign
7. TSI and DICKEY-john Purchased New Trade Show Displays from GLM Displays
8. Atomic Learning Takes Education on the Road with Formulate Fabric Displays from GLM Displays
9. GLM Displays Revamps Promotional Product Website
10. GLM Displays Adds New Division – GLM Promotions
11. GLM Displays Extends Store Wide Sale on All Banner Stands
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... The Microcompetition with Foreign DNA theory explains how latent ... viruses is the Epstein Barr Virus (EBV), and one of ... a chronic inflammatory disease that destroys the body’s joints. As ... have high concentrations of EBV DNA in their bodies (1). ...
(Date:1/15/2014)... , Jan. 15, 2014 TaiGen Biotechnology Company, ... exclusive agreement with R-Pharm, a leading Russian pharmaceutical company, ... the Russian Federation , ... Independent States (CIS). Nemonoxacin is a novel antibiotic for the ...
(Date:1/14/2014)... owners drew up their lists of New Year,s resolutions for 2014, ... my furry companion." Nowadays there are pet salons, dog and cat ... the little canine or feline darlings along wherever mommy or daddy ... toys at the pet store. But anyone who has ever lived ...
(Date:1/14/2014)... January 14, 2014 In recent years, ... and methods in product development and promotion has led ... This mistrust, fueled by concerns about the insidious impact ... reports of spectacular fines to the world’s biggest pharmas ...
Breaking Biology Technology:Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4New Year's Resolution: Give Pets the Gift of Top-Notch Health Care 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 3
... April 13 /PRNewswire-FirstCall/ - Vasogen Inc. (NASDAQ: VSGN ; ... months ended February 28, 2009. All dollar amounts referenced herein ... 28, 2009, our cash and cash equivalents totaled $7.3 million, ... incurred a net loss for the three months ended February ...
... Decisions Day, your choice in times of despair HOUSTON, ... .( www.usoncology.com ), supporting the nation,s foremost ... and manufacturers to advance cancer care in America, is ... National Healthcare Decisions Day ( www.nationalhealthcaredecisionsday.org ...
... Kan., April 13 Kansas State University ... thin material.Vikas Berry, assistant professor of chemical engineering, is ... developed carbon material that is only a single atom ... to the next level," Berry said. "Discovered only four ...
Cached Biology Technology:Vasogen Announces First Quarter 2009 Results 2Vasogen Announces First Quarter 2009 Results 3Vasogen Announces First Quarter 2009 Results 4Vasogen Announces First Quarter 2009 Results 5Vasogen Announces First Quarter 2009 Results 6Vasogen Announces First Quarter 2009 Results 7Vasogen Announces First Quarter 2009 Results 8Vasogen Announces First Quarter 2009 Results 9US Oncology Encourages Your Right to Decide 2US Oncology Encourages Your Right to Decide 3Connecting Materials Science With Biology, K-State Engineers Create DNA Sensors That Could Identify Cancer Using Material Only One Atom Thick 2Connecting Materials Science With Biology, K-State Engineers Create DNA Sensors That Could Identify Cancer Using Material Only One Atom Thick 3
(Date:4/24/2014)... Carolina State University and the University of North Carolina ... that could help identify arterial plaque that is at ... or stroke. , At issue is the plaque that ... of plaque are deemed "vulnerable," meaning that they are ... cause heart attack or stroke. , "Existing state-of-the-art technologies ...
(Date:4/24/2014)... puts out a welcome mat to bacteria seeking to invade, ... study published this week in the Proceedings of the ... battle between microbe and host that researchers can exploit to ... oft-studied plant Arabidopsis puts out a molecular signal ... a hostile army were unknowingly passing by a castle, and ...
(Date:4/23/2014)... release is available in French and German . ... or female? In humans and other mammals, the difference between sexes ... It is present only in males, where the two sexual chromosomes ... the Y is ultimately responsible for all the morphological and physiological ... been the case. A very long time ago, the X and ...
Breaking Biology News(10 mins):New ultrasound device may add in detecting risk for heart attack, stroke 2How a plant beckons the bacteria that will do it harm 2How a plant beckons the bacteria that will do it harm 3Male or female? 2Male or female? 3
... 16, 2010 VaxTrac announced today that it has ... Bill & Melinda Gates Foundation. The grant will support ... Thomas, Executive Director, titled "VaxTrac Pilot Program 1 Narnaul, ... grants announced by the Gates Foundation in the fifth ...
... published Friday in the leading scientific journal, Cell , ... cells using skin cells from four individuals with Rett syndrome. ... Dr. Alysson Muotri at the University of California, San Diego--a ... The article, titled ,A Model for Neural Development and Treatment ...
... the greater Himalayan region are retreating slowly, development agencies ... prepare for the many ways glacier melt is expected ... Programs that integrate health, education, the environment and social ... report states. "The extremely high altitudes and sheer mass ...
Cached Biology News:VaxTrac Receives $100,000 Grand Challenges Explorations Grant for Innovative Global Health Research 2Researchers 'grow Rett syndrome' in a Petri dish 2Time to prepare for climate change 2Time to prepare for climate change 3Time to prepare for climate change 4Time to prepare for climate change 5
Sterile, individually wrapped, 4mm Cuvettes...
... an enhanced form of Tobacco Etch Virus ... active, and significantly more stable than native ... Protease specifically recognizes a seven amino acid ... it useful for removing affinity tags from ...
... a fully flexible quadrupole MS detector optimized ... HPLC, 1-D and 2-D LC, as well ... incorporates a drying gas system to create ... especially for low-to-medium polarity compounds, while providing ...
S-100A10 (H-80)...
Biology Products: