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23ème congrès européen sur l'Hypertension et la Protection Cardiovasculaire
Date:6/25/2013

#233;sartan /amlodipine 40/10 mg qui a réduit la pression artérielle centrale de manière significativement plus importante. Plus la baisse de la pression artérielle est importante, plus le risque d'événements cardiovasculaires pourrait être faible," a commenté le Professeur Luis Ruilope, investigateur principal de l'étude SEVITENSION.

NOTES AUX RÉDACTEURS

A propos de Sevikar®

Sevikar® est une association fixe d'olmésartan et amlodipine :[10]

  • L'olmésartan est un antagoniste des récepteurs de l'angiotensine II (ARA II) qui agit en empêchant l'action de l'angiotensine II. L'angiotensine II provoque une vasoconstriction et entraîne la production d'aldostérone, une autre hormone qui stimule la rétention d'eau dans l'organisme. En bloquant l'action de l'angiotensine II, l'olmésartan dilate les vaisseaux sanguins et réduit le volume de liquide circulant dans le sang, faisant ainsi baisser la pression artérielle. L'amlodipine est un inhibiteur calcique à longue durée d'action indiqué pour réduire la pression artérielle. L'amlodipine agit en relâchant les muscles lisses de la paroi des artères, provoquant ainsi une diminution de la résistance périphérique totale et par conséquent une baisse de la pression artérielle.

En plus d'une action puissante sur la baisse de la pression artérielle, l'association Olmesartan et Amlodipine offre un mode d'administration pratique avec une seule prise par jour d'un comprimé, permettant à la majorité des patients d'atteindre leur objectif de pression artérielle.

A propos des associations thérapeutiques (d'après les recommandations européennes sur la prise en charge de l'hypertensio
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SOURCE Daiichi Sankyo Europe GmbH
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