Navigation Links
2011 Lasker Awards Honor Medical Research Pioneers
Date:9/12/2011

, 81, for saving millions of lives by discovering artemisinin, the most powerful anti-malarial drug currently available. An artemisinin-based drug combination is now the standard regimen for the disease, and the World Health Organization (WHO) lists artemisinin and related agents in its catalog of "Essential Medicines."

Tu's seminal work on malaria began amid the Cultural Revolution when the Chinese government launched a clandestine military project aimed at finding a remedy for the deadly scourge. The operation, dubbed Project 523 for the day it was announced – May 23, 1967 – set out to battle chloroquine-resistant malaria.

In keeping with Chairman Mao Zedong's desire to "explore and further improve" the "great treasure house" of traditional Chinese medicine, Tu combed ancient texts and folk remedies for possible leads. She collected 2000 recipes, which were then winnowed. By 1971, her team had made 380 extracts from 200 herbs. The researchers then assessed whether these substances could clear the malaria-causing parasite from infected mice.

One of the extracts from QinghaoArtemisia annua L., or sweet wormwood – dramatically inhibited parasite growth in the animals. The results were not reproducible, so Tu once again scoured the literature for possible explanations. Following clues, she and her team performed the extraction process at low temperatures. Tu's team also removed a harmful acidic portion of the extract that did not contribute to antimalarial activity and refined the preparation of the material in other ways. These innovations boosted potency and slashed toxicity. At a March 1972 meeting of the Project 523 group's key participants, she reported that the neutral plant extract wiped out the malarial-causing agent in the blood of mice and monkeys. A pure substance was obtained later that year which proved effective in treating people with malaria.

The first English-language scientific lite
'/>"/>

SOURCE The Albert and Mary Lasker Foundation
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related biology technology :

1. 2010 Lasker Awards Honor Trailblazers in Medical Research and Clinical Care
2. Debiopharm Group™ Presents the Debiopharm Group™ Life Sciences Award 2011 and two Junior Debiopharm Group™ Awards 2011 at the ISREC 2011 Life Sciences Symposium
3. 2011 Awards of World Cultural Council
4. BioInformatics LLC Announces the Life Science Industry Awards on November 15, 2011 in Washington, DC
5. Noted Author, Speaker, and Publisher, Gary Barg Joins BRAVE Awards Selection Committee
6. PAREXEL Named Company of the Year for the Pharmaceutical Industry in International Business Awards(SM)
7. Department of Defense Awards $5.7 Million Contract to PharmAthene for Nerve Agent Medical Countermeasure Program
8. TALEN® Access by Cellectis Bioresearch Receives "Most Innovative New Service 2011" Award at Life Science Awards
9. National Parkinson Foundation Awards More Than $1 Million for Research
10. The IPG Media Lab and Affectiva Announce Winners of First Annual Neuromarketing Awards
11. Department of Energy projects win 36 R&D100 Awards for 2011
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... The report “Pharmacy Automation Systems Market by ... Systems, Table-top Counters) by End-user (Inpatient Pharmacy Automation, ... to 2019” analyzes and studies the major market ... Asia-Pacific, and the Rest of the World (RoW). ... spread through 300 pages and in-depth TOC on ...
(Date:10/20/2014)... - BIOREM Inc. (TSXV: BRM) ("Biorem" or "the Company") today announced ... $5.8 million and provides a good start to Q4.  The orders ... and one in the Middle East ... levels," said Peter Bruijns , President & CEO. "Total bidding ... than they have been for any complete year since the company ...
(Date:10/20/2014)... October 20, 2014 OncLive® ... Kimmel Cancer Center at Thomas Jefferson University has ... Through the Strategic Alliance Partnership program, the Sidney ... collaborate to raise awareness of the Center’s cutting-edge ... other projects. Clinicians and other health care professionals ...
(Date:10/19/2014)... October 20, 2014 OCTOBER ... Meeting (ABIM). ABIM will take place ... information about ABIM 2014 is now available ... Delegates representing companies and organizations from all ... obtain information on the latest products and ...
Breaking Biology Technology:Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 2Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 3Pharmacy Automation Systems Market worth $4,566.2 Million by 2019 - New Research Report by MarketsandMarkets 4Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 2Sidney Kimmel Cancer Center at Thomas Jefferson University Partners With OncLive 3
... , ORANGE COUNTY, Calif., July 27 ... Board of Directors declared a quarterly dividend payout of seventeen cents ($0.17) ... all stockholders of record on August 10, 2009. This payout represents ... (Logo: http://www.newscom.com/cgi-bin/prnh/20031202/BECLOGO ) , , Beckman Coulter, Inc., ...
... , , , ... Calif. and LONDON, July 27 Amgen (Nasdaq: AMGN ... companies will share commercialization of Amgen,s monoclonal antibody denosumab for postmenopausal ... product is approved in these countries. Amgen will commercialize the ...
... , , , ... ZMH ; SWX: ZMH) today announced the launch of ... with teaching surgeons and subject matter experts to develop a unique ... Training and Surgeon-to-Surgeon programs under one, consolidated service offering, the enhanced ...
Cached Biology Technology:Amgen to Collaborate With GlaxoSmithKline to Commercialize Denosumab in Europe for Postmenopausal Osteoporosis (PMO) 2Amgen to Collaborate With GlaxoSmithKline to Commercialize Denosumab in Europe for Postmenopausal Osteoporosis (PMO) 3Amgen to Collaborate With GlaxoSmithKline to Commercialize Denosumab in Europe for Postmenopausal Osteoporosis (PMO) 4Amgen to Collaborate With GlaxoSmithKline to Commercialize Denosumab in Europe for Postmenopausal Osteoporosis (PMO) 5Amgen to Collaborate With GlaxoSmithKline to Commercialize Denosumab in Europe for Postmenopausal Osteoporosis (PMO) 6Amgen to Collaborate With GlaxoSmithKline to Commercialize Denosumab in Europe for Postmenopausal Osteoporosis (PMO) 7Zimmer Launches New Medical Education and BioSkills Training Program 2Zimmer Launches New Medical Education and BioSkills Training Program 3Zimmer Launches New Medical Education and BioSkills Training Program 4
(Date:10/16/2014)... -- NXT-ID, Inc. (NASDAQ: NXTD and ... focused on the growing mobile commerce market announces that ... Smart Wallet, at the 13 th annual Future ... conference on the intersection of technology and the economy. ... founder and publisher of the Strategic News Service™, the ...
(Date:10/15/2014)... our ability to assess the pandemic risk from strains ... we must not allow ourselves to become complacent that ... international consortium of scientists. , Influenza pandemics arise when ... yet to develop widespread immunity – spreads in the ... the past 100 years, the worst of which – ...
(Date:10/15/2014)... Gauß-Allianz has admitted Johannes Gutenberg University Mainz (JGU) ... science hub continues to maintain a significant nationwide ... , "The acceptance of Johannes Gutenberg University Mainz ... a milestone in the national and international competition ... state of Rhineland-Palatinate can be proud that Mainz ...
Breaking Biology News(10 mins):NXT-ID Inc. to Present at 13th Annual FiRe Conference 2NXT-ID Inc. to Present at 13th Annual FiRe Conference 3Scientists 'must not become complacent' when assessing pandemic threat from flu viruses 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 2Johannes Gutenberg University Mainz joins Germany's Gauss-Allianz as a full member 3
... in Nature , researchers at Brandeis University and the ... time shed light on a crucial step in the complex ... in the human cell and frequently at which point genetic ... they were able to crystallize a very large complex of ...
... does inflammation, brought on by stress, affect aging? What can ... crisis of an epidemic of neurologic diseases caused by a ... keep a rosy outlook in the face of inevitable decline? ... host of other questions are the focus of the inaugural ...
... Hughes Medical Research Institute today announced that two researchers ... scientists nationwide to be appointed HHMI Early Career Scientists. ... of the Center,s Basic Sciences Division, and Toshiyasu Taniguchi, ... Biology and Public Health Sciences divisions, each will receive ...
Cached Biology News:A splice of life 2Living long, living well 2Two Hutchinson Center researchers named HHMI Early Career Scientists 2
Synaptic Vesicle I Sampler Kit 10g each...
Handles samples from from 75l to 150l...
... phase reagent for Virus ... & unique water insoluble ... detergents and chaotropes; Engineered ... non-envelop viruses while preserving ...
Mouse monoclonal [N7519] to NR0B2 ( Abpromise for all tested applications). Antigen: E.coli expressed recombinant full length protein (Human) NR0B2 Entrez Gene ID: 8431 Swiss Protein ID: ...
Biology Products: