Navigation Links
2 problems in chemical catalysis solved
Date:12/20/2012

The research group of Professor Petri Pihko at the Department of Chemistry and the NanoScience Center of the University of Jyvskyl has solved two acute problems in chemical catalysis. The research has been funded by the Academy of Finland.

In the first project, the researchers designed a novel intramolecularly assisted catalyst for the synthesis of beta amino acids. Previously published catalysts work only with aromatic side chains in the imines, but the new catalyst designed at Jyvskyl does not have this limitation. The new method might find uses in the synthesis of beta amino acids, which are important building blocks for chemical biology. For the understanding of the catalytic mechanism and design of the catalyst, the researchers collaborated with the group of Imre Ppai (Hungarian Academy of Sciences, computational studies) and Academy Professor Kari Rissanen (Jyvskyl, X-ray characterisation of catalysts).

In the second project, the researchers identified a completely new mechanism for the amine-catalysed Michael addition reaction between aldehydes and nitroalkenes. The mechanism has been a source of intense discussion within the scientific community, with the groups of Professor Yujiro Hayashi (Tokyo), Professor Donna Blackmond (La Jolla, USA) and Professor Dieter Seebach (ETH, Switzerland) each presenting different possible mechanisms.

The new model proposed by the Pihko and Papai groups includes a new species, a six-membered ring, as the key on-cycle intermediate that is protonated in the rate-determining step. The work is a combination of computational and experimental studies that complement each other in understanding the mechanism and demonstrate how difficult mechanistic puzzles can be solved by joining the forces of both approaches.


'/>"/>

Contact: Petri Pihko
petri.pihko@jyu.fi
358-505-289-132
Academy of Finland
Source:Eurekalert  

Page: 1

Related biology technology :

1. Cold Adds Up to Sandy Victims' Mold Problems; Optimal Chemical Reaches Out to Help by Advising the Use of Molderizer
2. Entrepreneurs to Eat Problems for Breakfast in San Diego
3. A thin-skinned catalyst for chemical reactions
4. 20% Off Your Entire Order of Scientific, Technical, Medical (STM) Titles Until the End of December at Chemical Publishing Company
5. Chemical Publishing Company Announces its Niche Catalog in the Water Technology and Water Treatment Space
6. Piedmont Chemical Launches 100 Percent Renewable Polyester Polyols Leveraging Renewable Chemicals from DuPont Tate & Lyle Bio Products and Myriant Corporation
7. Researchers improve technology to detect hazardous chemicals
8. From lectures to explosives detection: Laser pointer identifies dangerous chemicals in real-time
9. Human brains share a consistent genetic blueprint and possess enormous biochemical complexity
10. ESTEVE Announces the Publication of Comprehensive Phase I Data for a Novel Oral, First-in-class New Chemical Entity (NCE),E-52862, a Sigma-1 Receptor Antagonist (S1RA) Being Developed for Pain
11. Chemical makes blind mice see; compound holds promise for treating humans
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
2 problems in chemical catalysis solved
(Date:7/27/2017)... ... July 27, 2017 , ... Margot Connor, ... position on Baltimore Business Journal’s 2017 Tech 10 List of “outstanding professionals in ... peers for contributions to the technology industry within their local community. Honorees are ...
(Date:7/26/2017)... ... July 26, 2017 , ... Franz Inc ., an ... technology for Knowledge Graphs, today announced Gruff v7.0 , the industry’s leading ... users and graph experts the ability to visually build queries and explore connections ...
(Date:7/26/2017)... ... July 25, 2017 , ... The leading Regenerative Veterinary Medicine ... cell therapy has been used on more than 13,000 animals. VetStem was ... fatal injuries to tendons and ligaments. , In 2003 VetStem signed a worldwide ...
(Date:7/26/2017)... , ... July 26, 2017 , ... ... Research Program at the National Institutes of Health (NIH), will be one of ... annual conference provides a platform for a multi-stakeholder discussion on the latest advancements ...
Breaking Biology Technology:
(Date:6/14/2017)... IBM ) is introducing several innovative partner startups at VivaTech ... startups and global businesses, taking place in Paris ... will showcase the solutions they have built with IBM Watson ... France is one of the most dynamic ... in the number of startups created between 2012 and 2015*, ...
(Date:5/16/2017)... 16, 2017  Veratad Technologies, LLC ( www.veratad.com ), ... and identity verification solutions, announced today they will participate ... May 15 thru May 17, 2017, in ... Trade Center. Identity impacts the lives ... today,s quickly evolving digital world, defining identity is critical ...
(Date:5/6/2017)... SINGAPORE , May 5, 2017 ... has just announced a new breakthrough in biometric ... that exploits quantum mechanical properties to perform ... new smart semiconductor material created by Ram Group ... across finance, entertainment, transportation, supply chains and security. ...
Breaking Biology News(10 mins):