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"Sitting Ducks" No Longer: Advance Flu Warning Permits Creation of Replikins Custom Synthetic Flu Vaccine in Animals
Date:11/10/2011

LONDON, Nov. 10, 2011 /PRNewswire/ -- Animals and humans no longer need to be "sitting ducks," oblivious to and unprepared for emergent infectious disease outbreaks. Rather than being caught off-guard by mass influenza outbreaks, UK-based biotech firm BioRadar Ltd. can successfully analyze the concentration and structure of the genomic Replikins in 'scout' viruses isolated from initial cases up to one year or longer, which provides advance warning of, and the ability to respond to the coming specific outbreaks (1,2).

(Photo:  http://photos.prnewswire.com/prnh/20111110/NY04916 )

More significantly, the advance warning affords BioRadar the time to produce specific solid-phase synthetic Replikins vaccines in seven days, and to test them thoroughly. Bulk production also takes days rather than months. Storage does not require refrigeration. For an example of current advance warning in H5N1 influenza, see Figure.

Specifically, BioRadar UK Ltd will make available the following synthetic updated Bogoch Replikins vaccines for animals: ReplikinsTransFlu™ against H5N1-H9N2-H1N1 Influenza Viruses in Poultry; ReplikinsFMD™ against Foot and Mouth Disease Virus in Livestock; ReplikinsTaura™ against Taura Syndrome Virus in Shrimp; and ReplikinsAMD™ against Aleutian Mink Disease Virus in mink.

The standard deviation of the mean (SD) indicates the population distribution of viruses with different Replikin Counts. At relatively low virus replication rates, the SD is small; the SD of the Replikin Counts increases with virus rapid replication, and an increase in the Mean follows (2).

BioRadar UK Ltd. has identified the specific Replikins in the H5N1 virus genome, both conserved and novel, which are currently building in concentration, increasing the risk of large outbreaks of H5N1 (Figure; Ref 3). The current H5N1 buildup, beginning in 2007 in birds, earl
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SOURCE BioRadar Ltd.
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