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$650 million commitment to Stanley Center at Broad Institute aims to galvanize mental illness research
Date:7/22/2014

olds," said Hyman. "But in the last few years, we've turned this featureless landscape into something we can exploit. If this is a wall, we've put toeholds into it. Now, we have to start climbing."

[For more information, see backgrounder on Shared Vision: Three lives converge to revitalize mental health research]

A unique and powerful research model

The Stanley Center's rapid progress was possible only because of the unique nature of the Broad Institute, its home institution. The Broad Institute grew from an MIT-based flagship center for the Human Genome Project, and generated a third of the DNA sequence data for that project – the single largest contribution to the effort. Formally founded in 2004 to fulfill the promise of the Human Genome Project by facilitating collaborative biomedical research across disciplines and institutions, it brings together faculty from Harvard University, the Massachusetts Institute of Technology, and the five major Harvard-affiliated hospitals: Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Dana-Farber Cancer Institute, and Massachusetts General Hospital. Celebrating its tenth anniversary in July, the Broad Institute is today home to a community of more than 2,000 members, including physicians, biologists, chemists, computer scientists, engineers, staff, and representatives of many other disciplines. Together, the Broad Institute community uses industrial-strength technological capabilities to take on challenges too great for any single lab or institution to tackle.

Broad investigators have led international consortia that have found thousands of genetic variants responsible for common diseases such as diabetes, heart disease, and Crohn's disease – and translated that knowledge into descriptions of the underlying biological processes, a critical step in the development of rationally designed drugs. They have discovered several hundre
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SOURCE Broad Institute
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