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$100 Million Gift Launches Sanford Stem Cell Clinical Center
Date:11/4/2013

tely creating much-needed drugs and therapies," said Goldstein, who will also serve as director of the new Sanford Center. "We have made profound progress in understanding the basic nature and abilities of stem cells. We know a great deal about how they work and differentiate and, in a number of cases, how to make them become the kinds of cells we think we need. Now we have to put that knowledge to the test in people, for people."

A great deal of the progress in stem cell research has occurred at UC San Diego School of Medicine. For example:

  • Catriona H.M. Jamieson, MD, PhD, associate professor of medicine at UC San Diego School of Medicine and director of the UC San Diego Moores Cancer Center stem cell program, and colleagues are conducting or planning trials for several stem cell-derived treatments of leukemia and other blood diseases that have shown encouraging results in animal models and human clinical trials.
  • Mark H. Tuszynski, MD, PhD, professor in the UC San Diego Department of Neurosciences and director of the UC San Diego Translational Neuroscience Institute, investigates both the slowly evolving neurological damage of Alzheimer's disease and the sudden, catastrophic consequences of traumatic spinal cord injuries. In the latter work, Tuszynski and colleagues recently reported using introduced neural stem cells to regenerate axon growth at the site of severe spinal cord injuries in rats, restoring some movement.
  • Goldstein's lab has created, for the first time, stem cell-derived, in-vitro models of sporadic and hereditary Alzheimer's disease using induced pluripotent stem cells from patients with AD. These functional Alzheimer's neurons in a dish promise to be an unprecedented tool for developing and testing drugs to treat the dreaded neurodegenerative disorder.

The Sanford Stem Cell Clinical Center will adva
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SOURCE University of California, San Diego
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