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hERG-CHO K1 Recombinant Cell Line from Upstate

ProductshERG-CHO K1 Recombinant Cell Line from Upstate
Company Upstate
Item hERG-CHO K1 Recombinant Cell Line
Price 
Description PrecisION Ion Channel Cell Lines
High Quality, Functionally-Validated, Ion Channel Cell Lines

Ion channels are well known for having a critical role in nerve and muscle function and consequently have a key function in pain, CNS and the heart. Drugs that modulate ion channels have been investigated in therapeutic areas, such as neuropathic pain, cardiac arrhythmia, hypertension, local anaesthesia, stroke, Parkinson's, obesity, epilepsy, diabetes and depression.

Historically, ion channels have been under exploited as drug targets primarily due to the lack of functional high throughput screening technologies. Over recent years, there has been considerable progress in this important area. However, now there is a requirement for high quality research tools that will allow the full benefit of the new screening technologies to be realised. Upstate has built a portfolio of ion channel cell lines to meet these new and evolving needs in the drug discovery industry.

Our ion channel cell lines are available off of the shelf. These cell lines are fully validated using electrophysiology, stable (>25 passage) and licensed for drug discovery research. The objective is to provide the pharmaceutical industry with a range of ion channel cell lines to support drug discovery, lead optimisation and safety pharmacology functions.

Mycoplasma Testing:
The cell line has been screened using the PCR VenorGem kit (Minerva Biolabs) to confirm the absence of Mycoplasma species.
Info UpstateUpstate
28820 Single Oak Drive
Temecula, CA 92590
Customer Service: 800-437-7500 or 951-676-8080
Tech Support: 800 548-7853
Fax Number: 800-437-7502 or 951-676-9209
Web Site: http://www.upstate.com
NOTE: Price information is approximate list price and actual prices may vary.

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Several Pichia pastoris strains are available to allow you to optimize expression and recovery of your protein of interest. Table 1 provides information to help you choose the appropriate strain....
Standard 2" or 3" Plastic can be ordered with 81 or 100 cell dividers. Mini 2" Plastics Boxes come standard with 25 cell dividers. Plastic boxes can also be ordered with corresponding freezer racks...
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5-bromouridine 5'-triphosphate (BrUTP) *10 mM in TE buffer*...
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