| Products | XpressPack™ Colorimetric Amplification Detection System, required for colorimetric XpressPack™ from CHEMICON |
| Company | CHEMICON |
| Item | XpressPack™ Colorimetric Amplification Detection System, required for colorimetric XpressPack™ |
| Price | $265.00 |
| Description | The CHEMICON XpressPack™ Colorimetric Detection System is intended for use in the qualitative detection of amplified DNA generated by an in-house validated in vitro nucleic acid amplification of a selected target of interest. • The CHEMICON XpressPack™ Colorimetric Detection System is a hybridization capture assay designed to detect amplified nucleic acid specific to the target of interest. Amplification reactions incorporating a biotinylated primer set (included in the XpressPack™ gene-specific kit) generate the required amplification product (amplicon). A portion of the resultant amplicon is added directly to the capture plate and denatured under alkali conditions separating the two DNA strands. The single-stranded amplicon is captured to the plate via hybridization with a specific oligonucleotide probe immobilized to the reaction well (target specific probe-coated plate included in the XpressPack™ gene-specific kit). The hybrid complex is then reacted with streptavidin conjugated to horseradish peroxidase. Unbound conjugate is removed by washing. When TMB substrate is added, a blue color develops. The reaction is stopped by the addition of an acid, changing the color to yellow. This color is quantitated using a microplate reader; the intensity of the color is directly proportional to the amount of amplicon present in the sample.
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| Info | CHEMICONCHEMICON International, Inc. 28820 Single Oak Drive Temecula, CA 92590 Customer Service: 800-437-7500 Tech Support: 800-437-7500 Fax Number: 800-437-7502 Web Site: http://www.chemicon.com |