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Smac/DIABLO, Human, Recombinant, E. coli from Calbiochem

ProductsSmac/DIABLO, Human, Recombinant, E. coli from Calbiochem
Company Calbiochem
Item Smac/DIABLO, Human, Recombinant, E. coli
Price $386.00

Second Mitochondria Derived Activator of Caspase/DIABLO

Liquid. In 100 mM KCl, 20 mM HEPES, pH 7.5 AVOID FREEZE/THAW CYCLES. Amino acid residues 56 - 239 of human Smac/DIABLO with a carboxy terminal His•Tag® sequence was expressed in and purified from E. coli. Smac/DIABLO is released along with cytochrome c during apoptosis and promotes caspase activation through the neutralization of IAPs, including XIAP (Cat. No. PF137). Biological activity: IC50~500-1500 nM to reverse the inhibition of XIAP (500 nM) on Z-DEVD-AFC (Cat. No. 264150) cleavage in activated cell extracts. Purity: ≥95% by SDS-PAGE. M.W. 22,000.

Info CalbiochemCalbiochem
Calbiochem, A Brand of EMD Biosciences, Inc.
10394 Pacific Center Court
San Diego, CA 92121

Customer Service:
(800) 854-3417
(858) 450 9600

Tech Support: 800-628-8470
Fax Number:
(800) 776-0999
(858) 453 3552

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NOTE: Price information is approximate list price and actual prices may vary.

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