| Products | Rat Leptin Assay Kit from Immuno-Biological Laboratories, Inc. | |
| Company | Immuno-Biological Laboratories, Inc. | |
| Item | Rat Leptin Assay Kit | |
| Price | ||
| Description | This kit #27295 has improved stability and convenience from the former kit #17295. However, the improved kit not only has overcome this problem but also produced some advantages as follows. At first, we have changed the formulation of HRP conjugated antibody from lyophilized product to liquid (0.4mL X 1). By this change, the stability of the conjugate has improved so that the conjugate can use for 12 months even in stored at 2-8C and use several times. And further, we have changed the formulation of TMB tablet (1mg X 2) to liquid (15mL X 1) with one bottle. By this change, the liquid TMB can use itself without preparation. And further, the stability of this liquid TMB has improved so that the liquid TMB can use for 12 months and use several times. Meantime, this change of formulation does not reflect change of performance. This meaning is that measurement value is not affected by this change in comparison with former kit The recessive obesity mutation, ob, identified in 1950, results in profound obesity and type II diabetes as part of a syndrome that resembles morbid obesity in humans. Freidmanfs group at Rockefeller University originally identified the obesity gene that encodes for Leptin in 1994. Leptin is a 16 KDa secreted protein produced by the ob gene. Adipose tissue produces Leptin and releases it into the bloodstream. As fat deposits grow, blood Leptin levels tends to increase. It has been suggested that Leptin acts as a lipostat, increasing as fat gets deposited into adipocytes. It is also found that the protein acts as a hormone instructing the brain to stop food consumption and to increase activity. The protein has also been shown to signal and probably control the onset of puberty. In addition, recent study shows Leptin acts as a potent inhibitor of bone formation through central nervous system. | |
| Info | Immuno-Biological Laboratories, Inc.8201 Central Ave NE Suite P Minneapolis, MN 55432
Fax Number: 763-780-2988 Web Site: http://www.ibl-america.com/ |