Navigation Links
Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents

ProductsRat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents
Company ABR-Affinity BioReagents
Item Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7
Price $295.00
Description Immunogen: Partially purified chicken intestinal cytoplasmic 1,25-(OH)2D3 receptor protein.

MA1-710 detects vitamin D receptor (VDR) from human, rat, mouse, hamster, chicken, amphibian, and fish tissues. This antibody does not cross-react with estrogen or glucocorticoid receptors. MA1-710 detects both the occupied and unoccupied forms of the receptor. MA1-710 has been successfully used in Western blot, immunocytochemistry, immunohistochemistry, immunoprecipitation and gel shift procedures. By Western blot, this antibody detects a 58 kDa and 60 kDa protein representing VDR in avians while the VDRs of mammalian species appear as single bands within the 52-55 kDa range. Immunohistochemical staining of VDR in cultured human skin fibroblasts with MA1-710 results in strong nuclear staining. MA1-710 antigen is partially purified chicken intestinal cytoplasmic 1,25-(OH)2D3 receptor protein. This antibody recognizes an epitope between amino acid residues 89 and 105 of human VDR. This region is just C-terminal to the DNA binding domain of the VDR.Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. The 1,25-dihydroxy-vitamin D3 receptor (VDR) belongs to the superfamily of steroid hormone receptors which includes estrogen, progesterone, glucocorticoid, androgen, and thyroid hormone receptors. Vitamin D modulates calcium and phosphorus homeostasis, bone remodeling, cell growth regulation, and differentiation. Studies have found VDR in the intestine, bone, kidney, epidermis, and cells of the endocrine immune system. Repression of T-cell proliferation and interleukin-2 (IL-2) gene expresion, for example, occurs when VDR binds within the IL-2 enhancer. Formation of VDR/retinoic X receptor (RXR) heterodimers in the presence of intracellular 1,25(OH)2D3 has been shown to interfere with assembly of nuclear factor of activated T-cells (NFATp)/Fos/Jun/DNA complex and subsequent IL-2 gene transcription.

Info ABR-Affinity BioReagentsABR-Affinity BioReagents
ABR-Affinity BioReagents Inc.
4620 Technology Drive, Suite 600
Golden, CO 80403
USA

Customer Service: +1.800.527.4535
Fax Number: +1.303.278.2424
Web Site: http://www.bioreagents.com
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. Rat Anti-Vitamin B3 Polyclonal Antibody, Unconjugated from Abcam
2. PolarScreen Androgen Receptor Competitor Assay Kit, Red from Molecular Probes (Invitrogen)
3. PolarScreen Progesterone Receptor Competitor Assay Kit, Far Red from Molecular Probes (Invitrogen)
4. PolarScreen Glucocorticoid Receptor Competitor Assay Kit, Far Red from Molecular Probes (Invitrogen)
5. Rabbit Anti-Neuromedin U Receptor 1 Polyclonal Antibody, Unconjugated from Novus Biologicals
6. Rabbit Anti-Human D4 Dopamine Receptor Antibody, Unconjugated from Sigma-Aldrich
7. Rabbit Anti-NPY Y2 Receptor Polyclonal Antibody, Unconjugated from GeneTex
8. Rabbit Anti-Leptin Receptor Polyclonal Antibody, Unconjugated from BioVision
9. Mouse Anti-Rat Golgi Snap Receptor Complex Member 2 (GOSR2) Monoclonal Antibody, Unconjugated from Lifespan Biosciences
10. Rabbit Anti-VIP Receptor 2 Polyclonal Antibody, Unconjugated from Abcam
11. Rabbit Anti-GABA A Receptor gamma 2 Polyclonal Antibody, Unconjugated from Abcam
Rabbit polyclonal to DcR2 ( Abpromise for all tested applications). entrezGeneID: 8793 SwissProtID: Q9UBN6...
...
...
Mouse Amphiregulin MAb (Clone 206220)...
Biology Products:
(Date:8/29/2014)... Davis have made some surprising discoveries about the ... immunodeficiency virus (SIV), the team found that specialized ... early responders to viral invasion and are the ... called interleukin-1 beta (IL-1β). , Though aimed ... of the gut epithelium that provides a barrier ...
(Date:8/29/2014)... Scientists at the Barshop Institute for Longevity and ... the UT Health Science Center at San Antonio, have ... the longest-lived rodent, the naked mole rat. , ... naked mole rats protects and alters the activity of ... proteins. , The factor also protects proteasome function in ...
(Date:8/29/2014)... recently, little has been known about what genetic changes ... of scientists, one of whom is a University of ... that genes controlling the development of the brain and ... The study was published Aug. 28 in Science ... is online at http://www.sciencemag.org/ ., The domestication of ...
Breaking Biology News(10 mins):The early cost of HIV 2Factor in naked mole rat's cells enhances protein integrity 2New research reveals how wild rabbits were genetically transformed into tame rabbits 2New research reveals how wild rabbits were genetically transformed into tame rabbits 3
... BMC Microbiology highlights some of the recent ... the genes involved in the complex interplay between microbes ... members of the international Plant-Associated Microbe Gene Ontology (PAMGO) ... include a language that gives researchers a shared vocabulary ...
... You may recall as a child catching the itchy red ... varicella zoster virus and was responsible for nearly 4 million ... (CDC), until a vaccine introduced in 1995 reduced that number ... suffered from chicken pox, the varicella zoster virus may still ...
... is trying to coax human stem cells to turn ... be used to replace damaged tissue in people with ... an assistant professor of chemical and molecular engineering in ... $150,000 two-year grant from the March of Dimes Foundation ...
Cached Biology News:Special issue of BMC Microbiology spotlights standardized language for describing microbes 2Special issue of BMC Microbiology spotlights standardized language for describing microbes 3Childhood chicken pox could affect oral health years later 2Researcher seeks to turn stem cells into blood vessels 2Researcher seeks to turn stem cells into blood vessels 3
(Date:8/30/2014)... August 31, 2014 The Global ... professional and in-depth study on the current state ... and China. , The report provides a basic ... industry chain structure. Global market analysis and Chinese ... on history, developments, trends and competitive landscape of ...
(Date:8/29/2014)... DIEGO, Aug. 29, 2014  Pfenex Inc. (NYSE ... the development of high-value and difficult to manufacture ... update and reported financial results for the second ... the successful completion of our initial public offering, ... our biosimilar product candidates, derived from our proprietary ...
(Date:8/29/2014)... of the most promising technologies for future quantum circuits ... instead of electrons. First, it is necessary to be ... control their direction. Researchers around the world have made ... now scientists at the Niels Bohr Institute have succeeded ... at a time and in a particular direction. The ...
(Date:8/29/2014)... The global companion diagnostics market ... It is expected to grow at a CAGR ... valued at $1.8 billion in 2013, according to ... , For more information regarding analysis details and ... research report, titled “Companion Diagnostics Market (Breast Cancer, ...
Breaking Biology Technology:Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 2Electrical Insulating Varnish Market World, China Regional Analysis & 2020 Forecasts Available at DeepResearchReports.com 3Pfenex Reports Second Quarter 2014 Results and Provides Business Update 2Pfenex Reports Second Quarter 2014 Results and Provides Business Update 3Pfenex Reports Second Quarter 2014 Results and Provides Business Update 4Pfenex Reports Second Quarter 2014 Results and Provides Business Update 5Pfenex Reports Second Quarter 2014 Results and Provides Business Update 6Pfenex Reports Second Quarter 2014 Results and Provides Business Update 7Pfenex Reports Second Quarter 2014 Results and Provides Business Update 8Breakthrough in light sources for new quantum technology 2Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 2Companion Diagnostics Market to Hit $5.6 Billion in 2019: Transparency Market Research 3