Navigation Links
Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents

ProductsRat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents
Company ABR-Affinity BioReagents
Item Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7
Price $295.00
Description Immunogen: Partially purified chicken intestinal cytoplasmic 1,25-(OH)2D3 receptor protein.

MA1-710 detects vitamin D receptor (VDR) from human, rat, mouse, hamster, chicken, amphibian, and fish tissues. This antibody does not cross-react with estrogen or glucocorticoid receptors. MA1-710 detects both the occupied and unoccupied forms of the receptor. MA1-710 has been successfully used in Western blot, immunocytochemistry, immunohistochemistry, immunoprecipitation and gel shift procedures. By Western blot, this antibody detects a 58 kDa and 60 kDa protein representing VDR in avians while the VDRs of mammalian species appear as single bands within the 52-55 kDa range. Immunohistochemical staining of VDR in cultured human skin fibroblasts with MA1-710 results in strong nuclear staining. MA1-710 antigen is partially purified chicken intestinal cytoplasmic 1,25-(OH)2D3 receptor protein. This antibody recognizes an epitope between amino acid residues 89 and 105 of human VDR. This region is just C-terminal to the DNA binding domain of the VDR.Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. The 1,25-dihydroxy-vitamin D3 receptor (VDR) belongs to the superfamily of steroid hormone receptors which includes estrogen, progesterone, glucocorticoid, androgen, and thyroid hormone receptors. Vitamin D modulates calcium and phosphorus homeostasis, bone remodeling, cell growth regulation, and differentiation. Studies have found VDR in the intestine, bone, kidney, epidermis, and cells of the endocrine immune system. Repression of T-cell proliferation and interleukin-2 (IL-2) gene expresion, for example, occurs when VDR binds within the IL-2 enhancer. Formation of VDR/retinoic X receptor (RXR) heterodimers in the presence of intracellular 1,25(OH)2D3 has been shown to interfere with assembly of nuclear factor of activated T-cells (NFATp)/Fos/Jun/DNA complex and subsequent IL-2 gene transcription.

Info ABR-Affinity BioReagentsABR-Affinity BioReagents
ABR-Affinity BioReagents Inc.
4620 Technology Drive, Suite 600
Golden, CO 80403
USA

Customer Service: +1.800.527.4535
Fax Number: +1.303.278.2424
Web Site: http://www.bioreagents.com
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. Rat Anti-Vitamin B3 Polyclonal Antibody, Unconjugated from Abcam
2. PolarScreen Androgen Receptor Competitor Assay Kit, Red from Molecular Probes (Invitrogen)
3. PolarScreen Progesterone Receptor Competitor Assay Kit, Far Red from Molecular Probes (Invitrogen)
4. PolarScreen Glucocorticoid Receptor Competitor Assay Kit, Far Red from Molecular Probes (Invitrogen)
5. Rabbit Anti-Neuromedin U Receptor 1 Polyclonal Antibody, Unconjugated from Novus Biologicals
6. Rabbit Anti-Human D4 Dopamine Receptor Antibody, Unconjugated from Sigma-Aldrich
7. Rabbit Anti-NPY Y2 Receptor Polyclonal Antibody, Unconjugated from GeneTex
8. Rabbit Anti-Leptin Receptor Polyclonal Antibody, Unconjugated from BioVision
9. Mouse Anti-Rat Golgi Snap Receptor Complex Member 2 (GOSR2) Monoclonal Antibody, Unconjugated from Lifespan Biosciences
10. Rabbit Anti-VIP Receptor 2 Polyclonal Antibody, Unconjugated from Abcam
11. Rabbit Anti-GABA A Receptor gamma 2 Polyclonal Antibody, Unconjugated from Abcam
... BL21 Star strains ... designed for improved protein ... expression systems (Figure 1). ... polymerase synthesizes mRNA more ...
... Ideal for small volume applications, including pediatric, neonatal, geriatric, general adult, veterinary and experimental animals. Automatic ... turn-on. ... ... ...
X-Gal (5-Bromo-4-Chloro-3-Indoyl-beta -D-Galactopyranoside)...
Human Jagged 2 Biotinylated Affinity Purified PAb...
Biology Products:
(Date:2/28/2020)... (PRWEB) , ... February 27, 2020 , ... ... broadcast 2Q/2020, will explore innovative treatment solutions for maladies, such as Inflammatory Bowel ... info. , This segment will focus on a novel platform developed by ...
(Date:2/28/2020)... N.M. (PRWEB) , ... February ... ... Development, LLC (VIC), has formed Filtravate, its newest portfolio company. Established to ... based on technology exclusively licensed from New Mexico State University (NMSU). The ...
(Date:2/26/2020)... ... February 25, 2020 , ... Renowned eye surgical practice led by Steven ... Texas to offer the FDA-approved, post-surgical, corrective Light Adjustable Lens (LAL) by RxSight™. Since ... excellent results. Dell Laser Consultants is also currently involved in the latest LAL FDA ...
Breaking Biology News(10 mins):
(Date:2/26/2020)... , ... February 25, 2020 , ... ... & Biosciences (DuPont) recently published the results of its safety assessment on the ... HMOs currently identified in human milk. These complex carbohydrates are indigestible and therefore ...
(Date:2/21/2020)... ... , ... Pharmaceutical manufacturers are under increasing pressure to fast-track ... approaches like ‘Industry 4.0’ and continuous manufacturing, combat the growing and intense competition ... with an industry with the world’s tightest regulations and complex value chains, what ...
(Date:2/11/2020)... ... February 11, 2020 , ... ... to announce the successful results from a long-term follow-up clinical study of ... interspinous fixation device (INSPAN LLC). Unlike extension block design, the Inspan device ...
(Date:2/3/2020)... ... February 03, 2020 , ... ... Firm Travel, Law Firm Travel, Technology Industry Travel and Biotech/Healthcare Industry Travel Indexes. ... Each Index illustrates the following statistics:, Average airfare ...
Breaking Biology Technology: