Navigation Links
Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents

ProductsRat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7 from ABR-Affinity BioReagents
Company ABR-Affinity BioReagents
Item Rat Anti-Vitamin D Receptor Monoclonal Antibody, Unconjugated, Clone 9A7
Price $295.00
Description Immunogen: Partially purified chicken intestinal cytoplasmic 1,25-(OH)2D3 receptor protein.

MA1-710 detects vitamin D receptor (VDR) from human, rat, mouse, hamster, chicken, amphibian, and fish tissues. This antibody does not cross-react with estrogen or glucocorticoid receptors. MA1-710 detects both the occupied and unoccupied forms of the receptor. MA1-710 has been successfully used in Western blot, immunocytochemistry, immunohistochemistry, immunoprecipitation and gel shift procedures. By Western blot, this antibody detects a 58 kDa and 60 kDa protein representing VDR in avians while the VDRs of mammalian species appear as single bands within the 52-55 kDa range. Immunohistochemical staining of VDR in cultured human skin fibroblasts with MA1-710 results in strong nuclear staining. MA1-710 antigen is partially purified chicken intestinal cytoplasmic 1,25-(OH)2D3 receptor protein. This antibody recognizes an epitope between amino acid residues 89 and 105 of human VDR. This region is just C-terminal to the DNA binding domain of the VDR.Steroid receptors are ligand-dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. The 1,25-dihydroxy-vitamin D3 receptor (VDR) belongs to the superfamily of steroid hormone receptors which includes estrogen, progesterone, glucocorticoid, androgen, and thyroid hormone receptors. Vitamin D modulates calcium and phosphorus homeostasis, bone remodeling, cell growth regulation, and differentiation. Studies have found VDR in the intestine, bone, kidney, epidermis, and cells of the endocrine immune system. Repression of T-cell proliferation and interleukin-2 (IL-2) gene expresion, for example, occurs when VDR binds within the IL-2 enhancer. Formation of VDR/retinoic X receptor (RXR) heterodimers in the presence of intracellular 1,25(OH)2D3 has been shown to interfere with assembly of nuclear factor of activated T-cells (NFATp)/Fos/Jun/DNA complex and subsequent IL-2 gene transcription.

Info ABR-Affinity BioReagentsABR-Affinity BioReagents
ABR-Affinity BioReagents Inc.
4620 Technology Drive, Suite 600
Golden, CO 80403
USA

Customer Service: +1.800.527.4535
Fax Number: +1.303.278.2424
Web Site: http://www.bioreagents.com
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. Rat Anti-Vitamin B3 Polyclonal Antibody, Unconjugated from Abcam
2. PolarScreen Androgen Receptor Competitor Assay Kit, Red from Molecular Probes (Invitrogen)
3. PolarScreen Progesterone Receptor Competitor Assay Kit, Far Red from Molecular Probes (Invitrogen)
4. PolarScreen Glucocorticoid Receptor Competitor Assay Kit, Far Red from Molecular Probes (Invitrogen)
5. Rabbit Anti-Neuromedin U Receptor 1 Polyclonal Antibody, Unconjugated from Novus Biologicals
6. Rabbit Anti-Human D4 Dopamine Receptor Antibody, Unconjugated from Sigma-Aldrich
7. Rabbit Anti-NPY Y2 Receptor Polyclonal Antibody, Unconjugated from GeneTex
8. Rabbit Anti-Leptin Receptor Polyclonal Antibody, Unconjugated from BioVision
9. Mouse Anti-Rat Golgi Snap Receptor Complex Member 2 (GOSR2) Monoclonal Antibody, Unconjugated from Lifespan Biosciences
10. Rabbit Anti-VIP Receptor 2 Polyclonal Antibody, Unconjugated from Abcam
11. Rabbit Anti-GABA A Receptor gamma 2 Polyclonal Antibody, Unconjugated from Abcam
... has been demonstrated that oxidative stress is ... cancer. Oxidative stress is the condition in ... physiological antioxidants exist leading to the damage ... to oxidative stress is through several antioxidant ...
... Versatile affinity matrix for the extraction ... proteins or other macromolecules, Applications: ,Reducing ... of the interaction of pure β-adrenergic ... Removing residual SDS in 6 M ...
Values of steady state parameters for enzyme activities are determined....
... can be used for the identification of potential ... renal and other diseases. Due to the fact ... amounts, it provides an attractive alternative to blood ... The ProteoSpin Urine Protein Concentration Micro Kit ...
Biology Products:
(Date:4/5/2017)... 2017  The Allen Institute for Cell Science today ... one-of-a-kind portal and dynamic digital window into the human ... first application of deep learning to create predictive models ... and a growing suite of powerful tools. The Allen ... future publicly available resources created and shared by the ...
(Date:4/4/2017)... April 4, 2017   EyeLock LLC , a ... the United States Patent and Trademark Office (USPTO) has ... the linking of an iris image with a face ... represents the company,s 45 th issued patent. ... very timely given the multi-modal biometric capabilities that have ...
(Date:3/30/2017)... , March 30, 2017 The research ... system for three-dimensional (3D) fingerprint identification by adopting ground breaking 3D ... a new realm of speed and accuracy for use in identification, ... an affordable cost. ... ...
Breaking Biology News(10 mins):
(Date:8/16/2017)... Ca (PRWEB) , ... August 16, 2017 , ... ... by changing into a different cell type. Many treatments for specific cancers, such ... prominent example of targeted treatment is androgen deprivation therapy for advanced prostate cancer. ...
(Date:8/16/2017)... , Aug. 16, 2017  This year,s edition of the Inc. ... in life sciences workforce solutions, has made the list for the third ... recognizes the nation,s fastest-growing private companies based on a set of quantitative ... which includes the fastest-growing companies in the Bay State ... Inc. 5000 ...
(Date:8/15/2017)... ... August 15, 2017 , ... Nanomedical ... and biotherapeutics development, announces the launch of the new NHS Agile biosensor ... kinetic binding data for a wide range of molecules, including small and large ...
(Date:8/15/2017)... ... August 15, 2017 , ... The Conference Forum and The ... through a series of upcoming panels and events. The partnership culminates with the ... Hotel in New York City. , “With our experience in producing the Immuno-Oncology 360° ...
Breaking Biology Technology: