|Products||Rabbit Anti-Peroxiredoxin 1 Polyclonal Antibody, Unconjugated from GeneTex|
|Item||Rabbit Anti-Peroxiredoxin 1 Polyclonal Antibody, Unconjugated|
|Description|| Rabbit polyclonal to Peroxiredoxin 1|
Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiolspecific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx6 belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20-30 kilodalton in molecular size and vary in subcellular localization: Prx1, 2, and 6 in cytosol, Prx3 in mitochondria, Prx 4 in ER and secretion, Prx 5 showing complicated distribution including peroxisome, mitochondria and cytosol.
Immunogen: Synthetic peptide: LVSDPKRTIAQD, corresponding to amino acids 103-114 of Human Peroxiredoxin 1.
Specificity: This antibody detects Peroxiredoxin 1 protein in human samples. The antibody is specific for Peroxiredoxin 1 and shows no cross reactivity with other Prx isoforms.
14785 Omicron Dr. Suite101
San Antonio, TX 78245
Customer Service: (877) 436-3839
Fax Number: (210) 677-8843
Web Site: http://www.genetex.com