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Rabbit Anti-Human COP9 signalosome complex subunit 2 Polyclonal Antibody, Unconjugated from Aviva Systems Biology

ProductsRabbit Anti-Human COP9 signalosome complex subunit 2 Polyclonal Antibody, Unconjugated from Aviva Systems Biology
Company Aviva Systems Biology
Item Rabbit Anti-Human COP9 signalosome complex subunit 2 Polyclonal Antibody, Unconjugated
Price $250.00
Description COPS2 is an essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP. COPS2 is also innvolved in early stage of neuronal differentiation via its interaction with NIF3L1.
Antigen Specificity: Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human COPS2 with an internal ID of P05504
Accession Number: NP_004227
Protein Size: 443
Computer-Predicted Molecular Weight: 52kDa
Quality Control: Rabbit Ig G is purified by peptide affinity chromatography method
ELISA Titre Using Peptide Based Assay: 1:62500
Suggested Working Dilution for Western Blot: Suggested dilution at 1 g/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000-100,000 as second antibody.
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