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Rabbit Anti-HDAC4 Polyclonal Antibody, Unconjugated from GeneTex

ProductsRabbit Anti-HDAC4 Polyclonal Antibody, Unconjugated from GeneTex
Company GeneTex
Item Rabbit Anti-HDAC4 Polyclonal Antibody, Unconjugated
Price $295.00
Description Rabbit polyclonal to HDAC4 - ChIP Grade

HDAC4 is a member of the class II mammalian histone deacetylases, which consists of 1084 amino acid residues. Its C-terminal sequence is highly similar to the deacetylase domain of yeast HDA1. HDAC4, unlike other deacetylases, shuttles between the nucleus and cytoplasm in a process involving active nuclear export. Association of HDAC4 with 14-3-3 results in sequestration of HDAC 4 protein in the cytoplasm. In the nucleus, HDAC4 associates with the myocyte enhancer factor MEF2A. Binding of HDAC4 to MEF2A results in the repression of MEF2A transcriptional activation. HDAC4 has also been shown to interact with other deacetylases such as HDAC3 as well as the corepressors NcoR and SMART.

Immunogen: Unfortunately, this information is considered to be commercially sensitive

Specificity: The antibody detects ~140 kDa histone deacetylase 4. It does not cross-react with other HDAC proteins including HDAC1, 2, 3, 5, 6, 7, and 8.
Info GeneTexGeneTex
14785 Omicron Dr. Suite101
San Antonio, TX 78245
Customer Service: (877) 436-3839
Fax Number: (210) 677-8843
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NOTE: Price information is approximate list price and actual prices may vary.

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