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Osteoclasts Culture Kit from B-Bridge International

ProductsOsteoclasts Culture Kit from B-Bridge International
Company B-Bridge International
Item Osteoclasts Culture Kit
Description Osteoclast cells form from a hematopoietic stem cells called monocytes. Osteoclasts resorb bone by attaching to the bone surface and lowering the surrounding pH to an acidic level of around 4.5. The bone mineral is then solubilized and the collagen degraded. Osteoclast differentiation and function is controlled primarily by Macrophage Colony-Stimulating Factor (M-CSF) and Receptor for Activation of Nuclear Factor Kappa B Ligand (RANKL). The absence of NF-Kappa B leads to the bone disease osteopetrosis and the absence of M-CSF results in the arrest of differentiation in the pre-osteoclast stage. B-Bridges Osteoclast Culture Kit includes cryopreserved osteoclast precursor (OCP) cells from bone marrow and culture medium containing M-CSF and RANKL for researchers studying osteoporosis, bone reabsorbtion, or other bone metabolism disorders.
Info B-Bridge InternationalB-Bridge International
320 Logue Avenue
Mountain View, CA 94043

Customer Service: 650-969-7727
Fax Number: 650-969-7737
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