Mouse Anti-Presenilin 2 Monoclonal Antibody, Unconjugated, Clone 198C679.2.1 from GeneTex

Products	Mouse Anti-Presenilin 2 Monoclonal Antibody, Unconjugated, Clone 198C679.2.1 from GeneTex
Company	GeneTex
Item	Mouse Anti-Presenilin 2 Monoclonal Antibody, Unconjugated, Clone 198C679.2.1
Price	$295.00
Description	Mouse monoclonal [198C679.2.1] to Presenilin 2 Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Two alternative transcripts of PSEN2 have been identified. Immunogen: Synthetic peptide (Human).
Info	GeneTex 14785 Omicron Dr. Suite101 San Antonio, TX 78245 Customer Service: (877) 436-3839 Fax Number: (210) 677-8843 Web Site: http://www.genetex.com

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TAG: Mouse Anti Presenilin Monoclonal Antibody Unconjugated Clone from GeneTex

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