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Mouse Anti-Presenilin 2 Monoclonal Antibody, Unconjugated, Clone 198C679.2.1 from GeneTex

ProductsMouse Anti-Presenilin 2 Monoclonal Antibody, Unconjugated, Clone 198C679.2.1 from GeneTex
Company GeneTex
Item Mouse Anti-Presenilin 2 Monoclonal Antibody, Unconjugated, Clone 198C679.2.1
Price $295.00
Description Mouse monoclonal [198C679.2.1] to Presenilin 2

Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP. Also, it is thought that the presenilins are involved in the cleavage of the Notch receptor, such that that they either directly regulate gamma-secretase activity or themselves are protease enzymes. Two alternative transcripts of PSEN2 have been identified.

Immunogen: Synthetic peptide (Human).
Info GeneTexGeneTex
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San Antonio, TX 78245
Customer Service: (877) 436-3839
Fax Number: (210) 677-8843
Web Site: http://www.genetex.com
NOTE: Price information is approximate list price and actual prices may vary.

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Attachments: Clip bar for tubes 10 to 19 mm in diameter Overall Dimension Height IC: 6 (15.2) Overall Dimension Length IC: 18.5 (46.9) Overall Dimension Width IC: 4 (10.2)...
Mixing speed from 750-3200RPM, small vortexing orbit of1.0mm...
This Universal 24" X 18" (61 X 45.7cm.) shaker platforms will accept any Thermo Forma shaker flask clip....
Spaced cover glasses to promote effective hybridization...
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