|Products||Mouse Anti-67kD Laminin Receptor Prediluted Monoclonal Antibody, Unconjugated, SPM278 from GeneTex|
|Item||Mouse Anti-67kD Laminin Receptor Prediluted Monoclonal Antibody, Unconjugated, SPM278|
|Description|| Product Mouse monoclonal [SPM278] to 67kD Laminin Receptor, prediluted|
Immunogen Small cell lung carcinoma N592 live cells (Human).
Reactivity / Specificity Cross-reacts with Human. Not yet tested in other species.
Background Information Laminin, one of the major glycoproteins of basement membrane, displays multiple biological activities which are mediated through its interaction with specific cell membrane receptors. Overexpression of Laminin Receptor is reportedly an independent prognostic factor in breast cancer and correlates with the dissemination of the tumor cells in bone marrow. Laminin Receptor appears to play an important role in tumor invasion and metastasis.
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